Results 51 to 60 of about 1,472,593 (206)

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Temperton, Nigel J., Claudia Trombetta, Emanuele Montomoli, Trombetta, Claudia Maria, Stuart Mather, Perini, Daniele, Daniele Perini, Claudia Maria Trombetta, Mather, Stuart, Temperton, Nigel, Trombetta, Claudia, Nigel Temperton, Montomoli, Emanuele   +12 more
core   +1 more source

Annual Universal Influenza Vaccination: Ready or Not? [PDF]

Clinical Infectious Diseases, 2006
Influenza causes annual worldwide epidemics of respiratory disease. Currently, the United States and many other countries recommend influenza vaccination for persons who are at high risk for influenza-related complications. This commentary explores the potential benefits of a policy advocating universal annual influenza vaccination and outlines ...
Bruce Gellin, John F. Modlin, Jon S. Abramson, Kathleen M. Neuzil, Susan E. Tamblyn   +4 more
openaire   +2 more sources

Hemagglutinin sequence conservation guided stem immunogen design from influenza A H3 subtype [PDF]

, 2015
Seasonal epidemics caused by influenza A (H1 and H3 subtypes) and B viruses are a major global health threat. The traditional, trivalent influenza vaccines have limited efficacy because of rapid antigenic evolution of the circulating viruses.
Citron, Michael, Ferrara, Francesca, Temperton, Nigel J., Flynn, Jessica A, Raghavan eVaradarajan, Vamsee Aditya Mallajosyula, V., Raghavan Varadarajan, Flynn, Jessica A., Temperton, Nigel J, Xiaoping eLiang, Vamsee Aditya Mallajosyula, V. Vamsee Aditya Mallajosyula, Michael Citron, Nigel J. Temperton, Xiaoping Liang, Mallajosyula, Vamsee Aditya V, Jessica A. Flynn, Liang, Xiaoping, Varadarajan, Raghavan, Michael eCitron, Francesca eFerrara, Nigel James Temperton, Jessica A Flynn, Francesca Ferrara, Mallajosyula, Vamsee V A   +24 more
core   +1 more source

Protective efficacy of a universal influenza mRNA vaccine against the challenge of H1 and H5 influenza A viruses in mice

mLife, 2023
Current influenza vaccines need to be updated annually owing to constant antigenic drift in the globular head of the viral surface hemagglutinin (HA) glycoprotein. The immunogenic subdominant stem domain of HA is highly conserved and can be recognized by
Yulei Li, Xi Wang, Xi Zeng, Wenbo Ren, Pu Liao, Baoli Zhu   +5 more
doaj   +1 more source

Influenza vaccination for immunocompromised patients : systematic review and meta-analysis from a public health policy perspective [PDF]

, 2011
Background: Immunocompromised patients are vulnerable to severe or complicated influenza infection. Vaccination is widely recommended for this group. This systematic review and meta-analysis assesses influenza vaccination for immunocompromised patients ...
Haroon, Sophie, Kerac, Marko, Wigglesworth, Neil, Kim, Sophie, Isba, Rachel, Wallace, Dean, Zanuzdana, Arina, Fisher, Paul, Hird, Caroline, Stevenson, Charlotte, McKenzie, Bruce C, Agboado, Gabriel, Weston, Rachel, Orton, Elizabeth, Haroon, Munib, Mukaigawara, Mitsuru, Augustine, Glenda, Butt, Mobasher, Puleston, Richard, Harris, Rebecca C, Hashim, Ahmed B, Dabke, Girija, Ahyow, Lauren, Morgan, Gemma, O'Brien, Mary, Roberts, Jonathan, Theaker, Sarah, Farmer, Siobhan, Rosser, Julia, Figureroa, Jose, Vinogradova, Yana, Ishola, David A, Peñalver, Javier, Beck, Charles R, Parish, Vivienne, Horiuchi, Hiroshi, Lingard, Liz, Enstone, Joanne, Howard, Robert, Greaves, Felix, Béchard-Evans, Laura, O'Boyle, Julie, Denness, Helene, Nguyen-Van-Tam, Jonathan S   +43 more
core   +6 more sources

Self-reported adverse reactions in 4337 healthcare workers immunizations against novel H1N1 influenza [PDF]

, 2011
Purpose: The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic influenza vaccine Methods: We ...
Harald Bias, David A Groneberg, Andres de Roux, Claus Meier-Wronski, Bias, Harald, Groneberg, Jan David Alexander, Joachim Seybold, Roux, Andrés de, Sabine Wicker, Meier-Wronski, Claus, Seybold, Joachim, Quarcoo, David, David Quarcoo, Nienhaus, Albert, Wicker, Sabine, Albert Nienhaus   +15 more
core   +1 more source

Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids

Angewandte Chemie, EarlyView.
Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar, Manas Joshi, Abhishek Chatterjee   +2 more
wiley   +2 more sources

A human multi-epitope recombinant vaccinia virus as a universal T cell vaccine candidate against influenza virus. [PDF]

PLoS ONE, 2011
There is a need to develop a universal vaccine against influenza virus infection to avoid developing new formulations of a seasonal vaccine each year. Many of the vaccine strategies for a universal vaccine target strain-conserved influenza virus proteins,
Alan G Goodman, Paul P Heinen, Susana Guerra, Aneesh Vijayan, Carlos Oscar S Sorzano, Carmen E Gomez, Mariano Esteban   +6 more
doaj   +1 more source

Universal Live-Attenuated Influenza Vaccine Candidates Expressing Multiple M2e Epitopes Protect Ferrets against a High-Dose Heterologous Virus Challenge

Viruses, 2021
The development of an influenza vaccine with broad protection and durability remains an attractive idea due to the high mutation rate of the influenza virus.
Daria Mezhenskaya, Irina Isakova-Sivak, Victoria Matyushenko, Svetlana Donina, Andrey Rekstin, Konstantin Sivak, Kirill Yakovlev, Anastasia Katelnikova, Kirill Kryshen, Valery Makarov, Larisa Rudenko   +10 more
doaj   +1 more source

Evidence and guidance on vaccine safety and effectiveness in subpopulations [PDF]

, 2011
This dissertation examines post-licensing vaccine safety and effectiveness against two major respiratory diseases in specific subpopulations, with emphasis on safety.
Mak, Tippi
core   +1 more source