Results 171 to 180 of about 124,046 (257)

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

UroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

Untargeted metabolomics reveals the metabolic basis of sugar-acid balance and quality differentiation in melon. [PDF]

Front Plant Sci
Wu J, Xu B, Yao H, Yang X, Liu Y, Chen G.   +5 more
europepmc   +1 more source

Gut microbiota dysbiosis and Long COVID susceptibility in chronic kidney disease

VIEW, EarlyView.
This study investigated gut microbiota dysbiosis and its association with Long COVID susceptibility in 224 hemodialysis patients. We found that 35.3% of patients developed Long COVID, characterized by neurological symptoms and elevated inflammatory markers, accompanied by significant gut microbiota alterations including enriched proinflammatory taxa ...
Meiling Jin, Lijie Ma, Yuqing Yuan, Kaiyi Zhu, Zhaohui Tong, Qianmei Sun   +5 more
wiley   +1 more source

Untargeted metabolomics reveals metabolic reprogramming and key metabolites in adherent and suspension Vero cells. [PDF]

Front Cell Dev Biol
Ji W, Chen Z, Yue X, Ma Z, Liu Z, Yang D, Sun N, Ma R, Qiao Z, Chen J, Wang J.   +10 more
europepmc   +1 more source

Microbial and Metabolic Correlates of Endometrial Dysfunction in Polycystic Ovary Syndrome: A Translational Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Women with polycystic ovary syndrome (PCOS) exhibit a substantially increased risk of miscarriage, yet the underlying mechanisms remain inadequately understood. This study aimed to investigate whether specific gut microbial dysbiosis and metabolic disturbance are associated with and may potentially contribute to endometrial ...
Mengyu Jing, Xi Chen, Meiyan Jiang, Huiya Fang, Xiaoming Zhu, Xuejing Jin, Yonghui Jiao, Ningning Hou, Weiwei Gong, Aixia Liu   +9 more
wiley   +1 more source

Correction: What's in a name? Metabolite identification: challenges and pitfalls in untargeted metabolomics. [PDF]

Metabolomics
Theodoridis G, Fiehn O, Holčapek M, Goodacre R, Raftery D, Plumb R, Ebbels TMD, Witting M, Gika H, Wilson ID.   +9 more
europepmc   +1 more source

Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model

Integrative Zoology, EarlyView.
UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang, Yuehua Wang, Hang Zhang, Guiping Xu, Shixia Xu, Guang Yang   +5 more
wiley   +1 more source

Integrating untargeted metabolomics and machine learning to reveal an aberration of sphingolipid metabolism in cardiometabolic HFpEF. [PDF]

Diabetol Metab Syndr
Mao X, Zhao L, Liu P, Wang Y, Shi S, Song Q.   +5 more
europepmc   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Column switching liquid chromatography dual mass spectrometry system for simultaneous untargeted metabolomics and targeted exposomics. [PDF]

Nat Commun
Wang Y, Hou D, Yuan Y, Guan P, Chen T, Guo X, You X, Shi X, Wang X, Wang Q, Liu X, Xu G.   +11 more
europepmc   +1 more source