Results 131 to 140 of about 14,579 (261)

Quercetin Has Antimetastatic Effects on Gastric Cancer Cells via the Interruption of uPA/uPAR Function by Modulating NF-κb, PKC-δ, ERK1/2, and AMPKα

Integrative Cancer Therapies, 2018
Gastric cancer (GC) is a malignancy with few effective treatment options after metastasis occurs. Quercetin (Qu) intake has been associated with reduced incidence and slow development of GC, probably due to its anti-proliferative and apoptotic effects ...
Hai Li PhD, Chen Chen PhD
doaj   +1 more source

Urokinase plasminogen activator receptor (uPAR) as a novel biomarker in prostate cancer.

, 2015
183 Background: New biomarkers are warranted to distinguish between indolent and aggressive prostate cancer (PCa). The urokinase plasminogen activator receptor (uPAR) plays an important role in pericellular proteolysis by binding urokinase plasminogen ...
M. Andreas Røder, Klaus Brasso, Gunilla Høyer-Hansen, Peter Iversen, Kasper Drimer Berg, Solvej Lippert, Ib Jarle Christensen   +6 more
core   +1 more source

Supplementary Figure 6 from Targeting uPAR with Antagonistic Recombinant Human Antibodies in Aggressive Breast Cancer

, 2023
Aaron M. LeBeau, Sai Duriseti, Stephanie T. Murphy, François Pépin, Byron Hann, Joe W. Gray, Henry F. VanBrocklin, Charles S. Craik   +7 more
openalex   +1 more source

Table S-3 from Molecular Effects of Stromal-Selective Targeting by uPAR-Retargeted Oncolytic Virus in Breast Cancer [PDF]

, 2023
Yuqi Jing, Valery Chávez, Yuguang Ban, Nicolas Acquavella, Doraya El-Ashry, Alexey Pronin, Xi Chen, Jaime R. Merchan   +7 more
openalex   +1 more source

uPAR depletion or blocking impairs migration of uPAR-expressing cells.

, 2014
A: Prostate carcinoma (PC3) cells were transfected with a uPAR-targeting siRNA or a non-targeting control siRNA; then, cells were partly lysed for Western blot analysis with a uPAR-specific antibody (left) and partly loaded in Boyden chamber and allowed ...
Nunzia Montuori (511913), Giuseppina Amodio (511911), Pia Ragno (342854), Paolo Remondelli (511912), Anna Li Santi (511910), Daniela Alfano (342853), Anna Gorrasi (511909)   +6 more
core   +1 more source

Leiomyoma stroma is a strong inducer of uPAR expression.

, 2014
Representative images of low- (EV1-sh3) and high- (uPAR1-NT) uPAR-expressing cells invading the ex vivo leiomyoma tissue. Cells were incubated for 7 and 14 days, as indicated. The tissue was IHC stained for uPAR.
Lars Uhlin-Hansen (350451), Nadezhda Latysheva (621786), Elin Hadler-Olsen (593784), Gunbjørg Svineng (593786), Robert Hanes (621788), Synnøve Magnussen (593782), Tuula Salo (114754), Emma Pirila (621787), Sonja E. Steigen (593785), Jan-Olof Winberg (350452)   +9 more
core   +1 more source

Strict correlation between uPAR and plakoglobin expression in pemphigus vulgaris.

, 2002
Recent studies have reported nuclear delocalization of plakoglobin in acantholytic pemphigus vulgaris cells. The objective of this study was to evaluate the role of plakoglobin in the pathogenesis of acantholysis in pemphigus vulgaris (PV) and its ...
Gaetano De Rosa, DE ROSA, GAETANO, G. De Rosa, Mignogna M. D., PANNONE, GIUSEPPE, RUBINI, Corrado, STAIBANO S, LO MUZIO L, FARRONATO G, P. F. Nocini, LO MUZIO, LORENZO, Pannone G., Farronato, G, M. D. Mignogna, De Rosa, G., C. Rubini, FerrariF, Nocini, Pf, FERRARI F, Corrado Rubini, Staibano S., RUBINI C, Staibano, S, G. Farronato, Giampietro Farronato, STAIBANO, STEFANIA, NOCINI, Pier Francesco, Nocini P.F., Giuseppe Pannone, MIGNOGNA, MICHELE DAVIDE, Ferrari, F, DE ROSA G., Mignogna, Md, Mignogna MD, Pier Francesco Nocini, PANNONE G, Farronato G., Ferrari F., Lorenzo Lo Muzio, G. Pannone, Stefania Staibano, Michele Davide Mignogna, S. Staibano, NOCINI PF, FERRARI, Francesca, Rubini, C, F. Ferrari, Lo Muzio L., Francesca Ferrari, L. Lo Muzio   +49 more
core   +1 more source

In vivo anti-metastatic effects of uPAR retargeted measles virus in syngeneic and xenograft models of mammary cancer

, 2014
Yuqi Jing, Marcela Toro Bejarano, Julia Zaias, Jaime R. Merchan   +3 more
openalex   +2 more sources

Survival by uPAR expression.

, 2019
Survival by uPAR expression in primary melanoma (upper panel) and metastatic tumors (lower panel), categorized according to the median in primary melanoma (SI 0–3 versus 4–9).
Rita G. Ladstein (6204701), Lars A. Akslen (158246), Ingeborg M. Bachmann (6204698), Cornelia Schuster (158231), Emilia Hugdahl (6204695)   +4 more
core   +1 more source

Urokinase-type Plasminogen Activator Receptor (uPAR) Ligation Induces a Raft-localized Integrin Signaling Switch That Mediates the Hypermotile Phenotype of Fibrotic Fibroblasts [PDF]

, 2014
L. Grove, Brian D. Southern, Tong Huan Jin, Kimberly E. White, Sailaja Paruchuri, Efrat Harel, Ying Wei, Shaik O. Rahaman, Candece L. Gladson, Qiang Ding, Charles S. Craik, Harold A. Chapman, Mitchell A. Olman   +12 more
openalex   +1 more source