Results 121 to 130 of about 14,076 (220)

uPAR depletion or blocking impairs migration of uPAR-expressing cells.

, 2014
A: Prostate carcinoma (PC3) cells were transfected with a uPAR-targeting siRNA or a non-targeting control siRNA; then, cells were partly lysed for Western blot analysis with a uPAR-specific antibody (left) and partly loaded in Boyden chamber and allowed ...
Nunzia Montuori (511913), Giuseppina Amodio (511911), Pia Ragno (342854), Paolo Remondelli (511912), Anna Li Santi (511910), Daniela Alfano (342853), Anna Gorrasi (511909)   +6 more
core   +1 more source

Urokinase plasminogen activator receptor (uPAR) as a novel biomarker in prostate cancer.

, 2015
183 Background: New biomarkers are warranted to distinguish between indolent and aggressive prostate cancer (PCa). The urokinase plasminogen activator receptor (uPAR) plays an important role in pericellular proteolysis by binding urokinase plasminogen ...
M. Andreas Røder, Klaus Brasso, Gunilla Høyer-Hansen, Peter Iversen, Kasper Drimer Berg, Solvej Lippert, Ib Jarle Christensen   +6 more
core   +1 more source

Metabolic factors regulate uPAR in vitro and in vivo

, 2008
Das Verständnis der Arterioskleroseentstehung und Progression ist auch heute noch unvollständig. Obwohl verschiedene Risikofaktoren identifiziert wurden, ist deren molekularbiologische Konsequenz nicht immer geklärt.
Aßmann, Anke
core   +1 more source

MMP-9 and uPAR regulated glioma cell migration [PDF]

, 2012
Integrin dependent and independent MMP-9 and uPAR signaling plays a key role in glioma cell migration and invasion. In this article, we comment on all the possible pathways and molecules associated with MMP-9- and uPAR- mediated glioma cell migration ...
Krishna Kumar Veeravalli (7947389), Jasti S. Rao (7925081)   +1 more
core  

uPAR immunohistochemistry in bladder urothelium with inflammation and CIS, respectively.

, 2015
The figure shows examples of uPAR negative benign-appearing urothelium with inflammation (A) and CIS (B). The tissue section was stained with a pAb against uPAR. The antibody was visualised with NovaRed.
Peter Thind (785525), Gunilla Høyer-Hansen (361869), Ole Didrik Laerum (785528), Benedikte Richter Iversen (785523), Martin Illemann (785524), Helle Pappot (785522), Hans von der Maase (785527), Lisbeth Salling (785526), Ib Jarle Christensen (399757), Line Hammer Dohn (785521)   +9 more
core   +1 more source

uPAR/suPAR Signaling and Organ Crosstalk in Cardiovascular-Kidney-Metabolic Syndrome. [PDF]

Circ Res
Hayek SS, Dryer SE.
europepmc   +1 more source

Soluble urokinase plasminogen activator receptor - What are the clinical potentials in psychiatry? [PDF]

Brain Behav Immun Health
Huber FG, Kristensen MWP, Nielsen MØ, Vang T, Nielsen J.   +4 more
europepmc   +1 more source

Inhibiting the uPAR/FPR1 interactions reduces blood-retinal barrier breakdown and improves retinal function in a rat model of diabetes. [PDF]

Front Neurosci
Canovai A, Amato R, Melecchi A, De Fenza M, Pavone V, D'Alonzo D, Cammalleri M, Dal Monte M.   +7 more
europepmc   +1 more source

Novel Roles of Urokinase- and Tissue-Type Plasminogen Activators in Substance Use Disorders: A Narrative Review of Molecular Mechanisms and Translational Perspectives. [PDF]

Int J Mol Sci
Bahi A, Steele S.
europepmc   +1 more source

uPAR exhibits age- and region-dependent expression in the brains of mice with Alzheimer's disease-like pathology. [PDF]

Brain Res
Sarko LE, Klaus E, Bondarenko V, Secker C, Mnuk MS, Marino KM, Shippy DC, Ulland TK, Saha K, Emborg ME, Metzger JM.   +10 more
europepmc   +1 more source