Results 121 to 130 of about 14,579 (261)
Discovery and Characterization of Human Recombinant anti-uPAR antibodies [PDF]
, 2012 The urokinase plasminogen activator receptor (uPAR) is involved in the proliferation and migration of cells from diverse lineages. As a heavily glycosylated, glycosyl phosphotidyl inositol (GPI) linked protein of approximately 300 amino acids, its ...
Duriseti, Sai
core
Abstract 831: uPAR Expression is Up-regulated in Cervical Cancer
, 2010 Hypoxia occurs during development of cervical cancer and is considered to correlate with its invasion. Hypoxia induces cancer cells to have more invasive property through the urokinase plasminogen activator receptor (uPAR) expression.
Hirotaka Nishi +6 more
core +1 more source
Constitutive endocytosis of uPAR is LRP-1-independent.
, 2013 Panel A: HEK293-uPAR were stained with R3 uPAR (green) and clathrin heavy chain antibodies (red) or with uPAR (red) and LRP-1 antibodies (green). Representative confocal images are displayed.
Francesco Blasi (61418) +4 more
core +1 more source
SPRY1 promotes the degradation of uPAR and inhibits uPAR-mediated cell adhesion and proliferation.
American journal of cancer research, 2014 Urokinase plasminogen activator receptor (uPAR) is a GPI anchored cell surface protein that is closely associated with invasion, migration, and metastasis of cancer cells. Many functional extracellular proteins and transmembrane receptors interact with uPAR. However, few studies have examined the association of uPAR with cytoplasm proteins.
Xiufeng, Liu +5 more
openaire +1 more source
Targeting uPAR in diabetic vascular pathologies*
Postępy Higieny i Medycyny Doświadczalnej, 2019 The uPAR protein is one of the most important elements in fibrinolysis. uPAR is associated with many biological processes, such as cell invasion, angiogenesis and cell proliferation. Because of its multifunctional character, it is difficult to produce an effective inhibitor of uPA-uPAR interactions.
Martyna Durak-Kozica +2 more
openaire +1 more source
Betydningen av uPAR på cellers evne til migrasjon og invasjon [PDF]
, 2009 For at en kreftsvulst skal kunne spre seg må kreftcellene ha evnen til å bryte ned den ekstracellulære matriksen (ECM) som holder dem på plass. De må også kunne bevege seg ut fra svulsten og over i lymfesystemet eller blod for å transporteres til et nytt
Seippel, Ninja Elise A
core
Staining intensity of uPAR and PAI-1 in OSCC.
, 2014 Representative photomicrographs of tissue microarray cores showing strong and weak staining for uPAR and PAI-1 in tumour islands: A) strong uPAR staining, B) weak uPAR staining, C) strong PAI-1 staining, and D) weak PAI-1 staining.
Lars Uhlin-Hansen (350451) +5 more
core +1 more source
Biomarker Insights, 2017 The urokinase plasminogen activator receptor (uPAR) has been proposed as a potential prognostic factor for various malignancies. The aim of this study is to assess the prognostic value of uPAR expression in neoplastic and stromal cells of patients with ...
Susanna WL de Geus +10 more
doaj +1 more source
Metabolic factors regulate uPAR in vitro and in vivo
, 2008 Das Verständnis der Arterioskleroseentstehung und Progression ist auch heute noch unvollständig. Obwohl verschiedene Risikofaktoren identifiziert wurden, ist deren molekularbiologische Konsequenz nicht immer geklärt.
Aßmann, Anke
core +1 more source