Results 111 to 120 of about 14,076 (220)
Data in Brief, 2015 The urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycolipid-anchored membrane protein often expressed in the microenvironment of invasive solid cancers and high levels are generally associated with poor patient prognosis (Kriegbaum ...
Baoyu Zhao +9 more
doaj +1 more source
Discovery and Characterization of Human Recombinant anti-uPAR antibodies [PDF]
, 2012 The urokinase plasminogen activator receptor (uPAR) is involved in the proliferation and migration of cells from diverse lineages. As a heavily glycosylated, glycosyl phosphotidyl inositol (GPI) linked protein of approximately 300 amino acids, its ...
Duriseti, Sai
core
Biomarker Insights, 2017 The urokinase plasminogen activator receptor (uPAR) has been proposed as a potential prognostic factor for various malignancies. The aim of this study is to assess the prognostic value of uPAR expression in neoplastic and stromal cells of patients with ...
Susanna WL de Geus +10 more
doaj +1 more source
, 2009 Das uPA (Urokinase)-/ uPAR (Urokinaserezeptor)- System ist primär als Fibrinolysesystem bekannt, stellt jedoch zusätzlich ein multifunktionelles System mit einem breitem Einflussspektrum auf inflammatorische Prozesse, Gefäßerkrankungen und Karzinomleiden dar.
Petzinger, Jutta +1 more
openaire +2 more sources
Constitutive endocytosis of uPAR is LRP-1-independent.
, 2013 Panel A: HEK293-uPAR were stained with R3 uPAR (green) and clathrin heavy chain antibodies (red) or with uPAR (red) and LRP-1 antibodies (green). Representative confocal images are displayed.
Francesco Blasi (61418) +4 more
core +1 more source
SPRY1 promotes the degradation of uPAR and inhibits uPAR-mediated cell adhesion and proliferation.
American journal of cancer research, 2014 Urokinase plasminogen activator receptor (uPAR) is a GPI anchored cell surface protein that is closely associated with invasion, migration, and metastasis of cancer cells. Many functional extracellular proteins and transmembrane receptors interact with uPAR. However, few studies have examined the association of uPAR with cytoplasm proteins.
Xiufeng, Liu +5 more
openaire +1 more source
uPAR/Cathepsin B Overexpression Reverse Angiogenesis by Rescuing FAK Phosphorylation in uPAR/Cathepsin B Down Regulated Meningioma [PDF]
, 2010 BACKGROUND: Meningiomas are the most commonly occurring intracranial tumors and account for approximately 15-20% of central nervous system tumors. Surgery and radiation therapy is a common treatment for brain tumors, however, patients whose tumors recur ...
Andrew J. Tsung (7925078) +8 more
core +2 more sources
Staining intensity of uPAR and PAI-1 in OSCC.
, 2014 Representative photomicrographs of tissue microarray cores showing strong and weak staining for uPAR and PAI-1 in tumour islands: A) strong uPAR staining, B) weak uPAR staining, C) strong PAI-1 staining, and D) weak PAI-1 staining.
Lars Uhlin-Hansen (350451) +5 more
core +1 more source
Betydningen av uPAR på cellers evne til migrasjon og invasjon [PDF]
, 2009 For at en kreftsvulst skal kunne spre seg må kreftcellene ha evnen til å bryte ned den ekstracellulære matriksen (ECM) som holder dem på plass. De må også kunne bevege seg ut fra svulsten og over i lymfesystemet eller blod for å transporteres til et nytt
Seippel, Ninja Elise A
core
Strict correlation between uPAR and plakoglobin expression in pemphigus vulgaris.
, 2002 Recent studies have reported nuclear delocalization of plakoglobin in acantholytic pemphigus vulgaris cells. The objective of this study was to evaluate the role of plakoglobin in the pathogenesis of acantholysis in pemphigus vulgaris (PV) and its ...
Gaetano De Rosa +49 more
core +1 more source