Results 91 to 100 of about 14,530 (214)
BMC Cancer, 2010 Background uPAR and MMP-9, which play critical roles in tumor cell invasion, migration and angiogenesis, have been shown to be associated with lipid rafts.
Estes Norman +5 more
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.Micro‐ and nano‐patterned elastin‐like recombinamer (ELR) hydrogels integrate bioactive matrix chemistry with defined surface topography. The combined cues promote rapid endothelial cell capture, alignment, and monolayer formation on soft substrates.
Jagoda Litowczenko +8 more
wiley +1 more source
Discovery and Characterization of Human Recombinant anti-uPAR antibodies [PDF]
, 2012 The urokinase plasminogen activator receptor (uPAR) is involved in the proliferation and migration of cells from diverse lineages. As a heavily glycosylated, glycosyl phosphotidyl inositol (GPI) linked protein of approximately 300 amino acids, its ...
Duriseti, Sai
core
Cytoplasmic and membrane staining of uPAR.
, 2014 Representative photomicrographs of tissue microarray sections stained for uPAR, showing typical A) membrane and B) cytoplasmic localized staining of the tumour cells. Scalebar = 50 µm.
Lars Uhlin-Hansen (350451) +5 more
core +1 more source
BMC Cancer, 2017 Background Tumor-specific biomarkers are a prerequisite for the development of targeted imaging and therapy in oral squamous cell carcinoma (OSCC). urokinase-type Plasminogen Activator Receptor (uPAR), Tissue Factor (TF) and Epidermal Growth Factor ...
Anders Christensen +11 more
doaj +1 more source
Advanced Science, Volume 13, Issue 52, 18 September 2026.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source
Engineering CAR‐Macrophages With Advanced Delivery Systems for Tissue Repair
Advanced Science, Volume 13, Issue 51, 14 September 2026.This review highlights how engineered macrophages equipped with chimeric antigen receptors (CAR) guide tissue repair by recognizing disease‐related targets, clearing harmful cells, and reshaping local immune environments. It summarizes macrophage biology, CAR design, delivery platforms, and functionalization strategies, and discusses emerging ...
Yixin Zhang +8 more
wiley +1 more source
Leiomyoma stroma is a strong inducer of uPAR expression.
, 2014 Representative images of low- (EV1-sh3) and high- (uPAR1-NT) uPAR-expressing cells invading the ex vivo leiomyoma tissue. Cells were incubated for 7 and 14 days, as indicated. The tissue was IHC stained for uPAR.
Lars Uhlin-Hansen (350451) +9 more
core +1 more source
Design and Preclinical Evaluation of Novel uPAR-Targeting Radiopeptides Modified with an Albumin-Binding Entity [PDF]
Several studies have focused on the development and application of radiolabeled DOTA-AE105 for targeting the urokinase-type plasminogen activator receptor (uPAR), which is expressed on various cancer types.
Deberle, Luisa M. (author) +13 more
core +1 more source
Blood Advances, 2017 : The plasminogen activation (PA) system has been implicated in driving inflammatory arthritis, but the precise contribution of PA system components to arthritis pathogenesis remains poorly defined. Here, the role of urokinase plasminogen activator (uPA)
Sherry Thornton +8 more
doaj +1 more source