Results 81 to 90 of about 14,076 (220)
uPAR immunohistochemistry in urothelial neoplasia of the bladder.
, 2015 The figure shows examples of different uPAR scores at the invasive front of the tumour: uPAR score = 0 (no uPAR positive cells detected), uPAR score = 3 (between 5% and 10% positive cells), and uPAR score = 6 (>70% positively stained cells).
Peter Thind (785525) +9 more
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Histopathology, EarlyView.TAC/SARIFA, defined by direct tumour–adipocyte contact at the invasion front, represents a reproducible, biologically meaningful H&E biomarker with consistent adverse prognostic associations in CRC. Aims Direct tumour‐adipocyte interaction at the invasion front, termed Stroma AReactive Invasion Front Areas (SARIFA), has recently emerged as a novel H&E ...
Nic G Reitsam +3 more
wiley +1 more source
Nephrology Dialysis Transplantation, 2020 Abstract Background and Aims The role of suPAR as a biomarker and/or causative factor in the pathogenesis of recurrent FSGS remains unclear (Harel E., et al. Transplantation 2020; 104:54-60). While anti-suPAR antibodies have been shown to block suPAR induced podocyte injury in mouse models of FSGS ...
Minnie Sarwal +5 more
openaire +1 more source
International Journal of Dental Hygiene, EarlyView.ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur +6 more
wiley +1 more source
Data in Brief, 2017 The data presented herein are connected to our research article (doi: 10.1016/j.biocel.2017.04.012) [1], in which we investigated the functional connections between the urokinase receptor (uPAR), and the ezrin/radixin/moesin (ERM) proteins, moesin and merlin [1]. Firstly, a model of action is proposed that enlightens how uPAR regulates distal integrins.
Degryse, Bernard +7 more
openaire +5 more sources
, 2015 In stage B patients, (a): overall survival was significantly reduced with uPARE positive in central region of tumour (n = 125) and (b): with strong uPARE in invasive front of tumours (n = 168).
Julie Fletcher (562693) +9 more
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Advanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.Micro‐ and nano‐patterned elastin‐like recombinamer (ELR) hydrogels integrate bioactive matrix chemistry with defined surface topography. The combined cues promote rapid endothelial cell capture, alignment, and monolayer formation on soft substrates.
Jagoda Litowczenko +8 more
wiley +1 more source
FPR1 co-localizes with uPAR on the surface of uPAR-expressing HEK-293 cells.
, 2014 HEK-293 cells stably transfected with uPAR cDNA (uPAR-293 cells) were seeded on glass coverslips and transiently transfected with FPR1 cDNA. After 24 h, cells were incubated for further 24 h in culture medium (DMEM) containing 10% serum (Basal) or in ...
Nunzia Montuori (511913) +6 more
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Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.This study screened hypoxia‐ischemia hub genes for AMI through transcriptomic bioinformatics and animal tests. Merging two GEO datasets yielded 633 DEGs; intersection with GeneCards hypoxia genes produced 21 HIRGs. PPI network and random forest identified core PLAUR and IL1B, whose diagnostic value was validated by GSE66360 via ROC, calibration, and ...
Longsheng Zhang, Ning Liang
wiley +1 more source
uPAR is constitutively internalized in the absence of ligands.
, 2013 In all cases, the images presented are representative of 3–5 independent experiments. Panel A shows a biotinylation assay performed in HT1080 cells.
Francesco Blasi (61418) +4 more
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