Results 101 to 110 of about 8,024 (201)

Protecting the proteome: Eukaryotic cotranslational quality control pathways. [PDF]

open access: yes, 2014
The correct decoding of messenger RNAs (mRNAs) into proteins is an essential cellular task. The translational process is monitored by several quality control (QC) mechanisms that recognize defective translation complexes in which ribosomes are stalled on
Bennett, Eric J, Lykke-Andersen, Jens
core   +2 more sources

RNA‐binding proteins orchestrating immunity in plants

open access: yesThe Plant Journal, Volume 123, Issue 5, September 2025.
SUMMARY RNA‐binding proteins (RBPs) direct the function and fate of RNA throughout the RNA lifecycle and play important roles in plant immunity, orchestrating the post‐transcriptional reprogramming of the transcriptome following induction of plant immune responses, a process that we term ‘RBP‐mediated immunity’. Although the importance of specific RBPs
Marcel Bach‐Pages   +4 more
wiley   +1 more source

TOP1α, UPF1, and TTG2 regulate seed size in a parental dosage-dependent manner.

open access: yesPLoS Biology, 2020
Cues of maternal and paternal origins interact to control seed development, and the underlying molecular mechanisms are still far from clear. Here, we show that TOPOISOMERASE Iα (TOP1α), UP-FRAMESHIFT SUPPRESSOR 1 (UPF1), and TRANSPARENT TESTA GLABRA2 ...
Chengxiang Li   +6 more
doaj   +1 more source

An atlas of chromatoid body components [PDF]

open access: yes, 2014
The genome of male germ cells is actively transcribed during spermatogenesis to produce phase-specific protein-coding mRNAs and a considerable amount of different noncoding RNAs. Ribonucleoprotein (RNP) granule-mediated RNA regulation provides a powerful
Chalmel, F.   +11 more
core   +3 more sources

RNA Epigenetics in Cancer: Current Knowledge and Therapeutic Implications

open access: yesMedComm, Volume 6, Issue 8, August 2025.
RNA epigenetics regulates cancer through RNA modifications, splicing, transport, and translation. Key components include m⁶A writers, splicing factors, RBPs, and nuclear export machinery. Aberrant RNA metabolism drives tumor progression and immune evasion.
Shanhe Huang   +4 more
wiley   +1 more source

Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors [PDF]

open access: yes, 2018
Nonsense-mediated decay is well known by the lucid definition of being a RNA surveillance mechanism that ensures the speedy degradation of mRNAs containing premature translation termination codons.
Kleinschmidt, Nicole   +5 more
core  

The salicylic acid dependent and independent effects of NMD in plants [PDF]

open access: yes, 2012
In eukaryotes, nonsense-mediated mRNA decay (NMD) targets aberrant and selected non-aberrant mRNAs for destruction. A recent screen for mRNAs showing increased abundance in Arabidopsis NMD-deficient mutants revealed that most are associated with the ...
Ashworth, Mary   +4 more
core   +1 more source

Conservation of Nonsense-Mediated mRNA Decay Complex Components Throughout Eukaryotic Evolution [PDF]

open access: yes, 2017
Nonsense-mediated mRNA decay (NMD) is an essential eukaryotic process regulating transcript quality and abundance, and is involved in diverse processes including brain development and plant defenses.
Causier, B   +5 more
core   +3 more sources

Experimental Evidence on the Multibidding Mechanism [PDF]

open access: yes
Pérez-Castrillo and Wettstein (2002) and Veszteg (2004) propose the use of a multibidding mechanism for situations where agents have to choose a common project. Examples are decisions involving public goods (or public "bads").
David Perez-Castrillo, Robert F. Veszteg
core  

UPF1 alleviates the progression of glioma via targeting lncRNA CYTOR.

open access: yesEuropean review for medical and pharmacological sciences, 2019
To uncover the role of UPF1 in alleviating the progression of glioma via targeting long non-coding RNA (lncRNA) CYTOR and underlying mechanism.A total of 30 glioma tissues surgically resected from glioma patients and 30 brain tissues were collected from brain trauma patients undergoing craniotomy during the same period.
Zou, S.-F.   +5 more
openaire   +2 more sources

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