Results 101 to 110 of about 5,540 (157)

Proximity labeling puts ZFP36L1 as central hub for posttranscriptional regulation networks in T cells. [PDF]

Life Sci Alliance
Jurgens AP, Popović B, van Alphen FP, Steinmetz M, Wardak L, Bradarić A, Engels S, van der Zwaan C, van den Biggelaar M, Hoogendijk AJ, Béthune J, Wolkers MC.   +11 more
europepmc   +1 more source

Correction: Regulation of oncogenic C-terminal truncated p53β protein isoform expression by SRSF3-UPF1 splicing and surveillance axis. [PDF]

Cell Biosci
Jeong J, Hong D, Park TY, Hur J, Koo T, Jeong S.   +5 more
europepmc   +1 more source

3'UTR-directed, kinase-proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells. [PDF]

iScience
Salotti J, Asif N, Basu S, Das A, Hu L, Yang M, Karim B, Saylor K, Martin N, Scheiblin DA, Misra S, Luke BT, Andresson T, Yi M, Galloux M, Lockett S, Tessarollo L, Johnson PF.   +17 more
europepmc   +1 more source

TDP-43 promotes allergen-induced inflammation and influenza A virus replication in airway epithelium. [PDF]

Nat Commun
Yuan Y, Tang W, Feng X, Zhang C, Liao Y, Tang M, He J, Wan S, Pan G, Lai X, Xue Q, Wang J.   +11 more
europepmc   +1 more source

Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome

The RNA helicase UPF1 shapes the transcriptome as the core factor of nonsense-mediated mRNA decay (NMD). The essential role of UPF1 in human cells has impeded efforts to delineate its directly regulated transcripts and molecular function.
Landthaler, Markus, Popp, Oliver, Mertins, Philipp, Wallmeroth, Damaris, Becker, Kerstin, Wulf, Paul O., Reinecke, Lucie, Del Giudice, Simone, Wyler, Emanuel, Polkovnychenko, Karina, Riedel, Maximilian, Teixeira Alves, Luiz Gustavo, Benlasfer, Nouhad, Boehm, Volker, Franitza, Marek, Gehring, Niels H.   +15 more
core   +1 more source

Nonsense-mediated mRNA decay: friend or foe in cancer biology? [PDF]

Cell Commun Signal
Wang Y, He C, Chen C, Ma X, Gao X, Li G, Li T.   +6 more
europepmc   +1 more source

LINC00839 transcriptionally activated by ELK1 represses ferroptosis in nasopharyngeal carcinoma by regulating UPF1/RCHY1/DJ-1 axis. [PDF]

NPJ Precis Oncol
Liu F, Li Y, Liu H, Tang L, Fang S, Wang X, Chen P, Wang H, Bao M, He B, Guo Z.   +10 more
europepmc   +1 more source

NMD takes two PIN domains to tango. [PDF]

RNA
Mühlemann O, Karousis ED.
europepmc   +1 more source

Nonsense-mediated mRNA decay and associated splicing patterns in neurodevelopmental disorders. [PDF]

Front Mol Biosci
Anisimova P, Filat'eva A, Tarabykin V, Kondakova E.   +3 more
europepmc   +1 more source

LncRNA Gas5, a Target of the Nonsense-Mediated Decay Pathway in the Brain, Regulates Neuroinflammation and Neurodegenerative Disease Pathways in a Tauopathy Mouse Model. [PDF]

Int J Mol Sci
Krause-Hauch M, Wang B, Patel RS, Verdina L, Hedrick A, Blair LJ, Dharap A, Cai J, Patel NA.   +8 more
europepmc   +1 more source