Results 181 to 190 of about 75,036 (262)
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery
MedComm – Oncology, Volume 5, Issue 1, March 2026.This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem +9 more
wiley +1 more source
PLoS Genetics, 2005 The unfolded protein response (UPR) is an adaptive signaling pathway utilized to sense and alleviate the stress of protein folding in the endoplasmic reticulum (ER). In mammals, the UPR is mediated through three proximal sensors PERK/PEK, IRE1, and ATF6.
doaj +1 more source
Plant, Cell &Environment, Volume 49, Issue 3, Page 1544-1560, March 2026.ABSTRACT Transpiration restriction under high vapour pressure deficit (VPD), measured indoors with individual plants, increases water use efficiency (WUE). However, VPD is not the only factor driving transpiration, individual plants in a field rapidly become a canopy, and reports on the transpiration restriction versus WUE are scant.
Raphaël Pilloni +12 more
wiley +1 more source
FEBS Open Bio, Volume 16, Issue 2, Page 340-351, February 2026.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
Mammalian ECD protein is a novel negative regulator of the PERK arm of the unfolded protein response [PDF]
, 2017 Ammons, Shalis A +10 more
core +2 more sources