Results 21 to 30 of about 101,011 (227)
Biology Open, 2019 The destruction of pancreatic β cells leads to reduced insulin secretion and eventually causes diabetes. Various types of cellular stress are thought to be involved in destruction and/or malfunction of these cells. We show that endoplasmic reticulum (ER)
Hiroka Katsube +3 more
doaj +1 more source
NF-κB signaling and crosstalk during carcinogenesis
4 open, 2019 Transcription factors (TFs) are proteins that control the transcription of genetic information from DNA to mRNA by binding to specific DNA sequences either on their own or with other proteins as a complex.
Brücher Björn L.D.M. +2 more
doaj +1 more source
Effectors Targeting the Unfolded Protein Response during Intracellular Bacterial Infection
Microorganisms, 2021 The unfolded protein response (UPR) is a homeostatic response to endoplasmic reticulum (ER) stress within eukaryotic cells. The UPR initiates transcriptional and post-transcriptional programs to resolve ER stress; or, if ER stress is severe or prolonged,
Manal H. Alshareef +2 more
doaj +1 more source
Angewandte Chemie, EarlyView.This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen +3 more
wiley +2 more sources
ITALY AT THE UPR: RESPECTING RIGHTS IN MIGRATION POLICY FROM 2019 TO THE PRESENT DAY
, 2023 openL’elaborato si propone di condurre un’analisi delle raccomandazioni rivolte all'Italia nel contesto dell’Universal Periodic Review (UPR) del 2019, concentrandosi sul tema dei diritti dei rifugiati e dei richiedenti asilo, per poi valutare in che ...
DE GREGORI, PAOLO
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Study of Dissolved Organic Carbon Concentration in KHDTK Forest Peatland Area, Central Kalimantan, Indonesia [PDF]
, 2021 The study was conducted to determine whether are differences in dissolved organic carbon (DOC) in three different types of peatland conditions. The study was conducted from March 1st to April 30, 2020.
Pratama, Galih Widhi +4 more
core +1 more source
Empowering Civil Society Organisations at the UPR - Strengthening Implementation of Recommendations from the UN's Universal Periodic Review [PDF]
The aim of this study is to empower civil society organisations whenengaging with the UPR, in turn strengthening the domestic implementationof UPR recommendations.
Oleschuk, Melisa, Storey, Alice
core +3 more sources
Pengembangan Perangkat Lunak Generate File Untuk Migrasi Data EPSBED Ke Format Table Feeder PDDIKTI
Jurnal Saintekom, 2017 Based on SK-03, DIKTI requires all universities provide a report on each semester that corresponding to the report format named EPSBED. EPSBED report is one indicator of a study program at the college as it is called active and abiding by the principle ...
Viktor Handrianus Pranatawijaya
doaj +1 more source
Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells. [PDF]
PLoS ONE, 2013 The unfolded protein response (UPR) is an endoplasmic reticulum (ER)-based cytoprotective mechanism acting to prevent pathologies accompanying protein aggregation. It is frequently active in tumors, but relatively unstudied in gliomas.
Laura M Epple +15 more
doaj +1 more source