Results 121 to 130 of about 26,862 (228)
This study detected the diet and gut microbiota of great bustards and common cranes in the wintering duration in the Yellow River Wetlands of Inner Mongolia using high‐throughput sequencing technology. This study indirectly indicated that great bustards and common cranes are well‐adapted to the environment of the Yellow River Wetlands during the ...
Li Gao +4 more
wiley +1 more source
Time‐dependent fermentation caused dynamic changes in the bioactive constituents of white corn steep liquor and improved its antioxidant, antidiabetic, and antiobesogenic activities in vitro. ABSTRACT The present study investigated the effect of crude fermentation on white corn steep liquor and its bioactive constituents in the management of metabolic ...
Lemohang Gumenku +5 more
wiley +1 more source
Identification of Natural and Artificial Modifications in DNA at the Nanometer Level
Short single‐ and double‐stranded DNA sequences with natural and artificial markers are examined at ambient conditions using TERS to identify and localize the labelled nucleobases. The differences between single‐ and double‐stranded DNA should provide clear experimental evidence of the extreme surface sensitivity of TERS.
Tanja Deckert‐Gaudig +4 more
wiley +1 more source
DNA Distortion Caused by Uracil-Containing Intrastrand Cross-Links
Four uracil-containing intrastrand cross-links have been detected in human cells upon UV irradiation of 5-bromouracil-containing DNA, namely 5′-G[8-5]U-3′, 5′-U[5-8]G-3′, 5′-A[8-5]U-3′, and 5′-A[2-5]U-3′.
Stacey D. Wetmore (696456) +2 more
core +2 more sources
Pharmacological characterization of Uracil nucleotide-sensitive P2Y receptors in mouse ileum
Since uracil nucleotide-preferring receptors, belonging to the P2Y receptor family and responding to either uridine triphosphate (UTP) or uridine diphosphate (UDP), have been proposed to be present at different cellular level in the gut, regulating ...
DI CRISTOFALO, AC +4 more
core
Udgivelsesdato: March 16, 1999Phosphoribosyltransferases catalyze the formation of nucleotides from a nitrogenous base and 5-phosphoribosyl-a-1-pyrophosphate (PRPP).
Lundegaard, Claus, Jensen, Kaj Frank
core +1 more source
The Role of N6‐Methyladenosine Modification in Health and Disease
N6‐methyladenosine (m6A) is the most prevalent internal RNA modification in eukaryotes, acting as a pivotal epitranscriptomic regulator of RNA metabolism. This modification plays a dual role: it maintains physiological homeostasis under normal conditions but drives disease progression when dysregulated.
Linghuan Li +6 more
wiley +1 more source
Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang +7 more
wiley +1 more source
Investigation of the role and mechanism of effect of nucleotides on the isolated hearts of molluscs
1. All the four groujis of nucleotides investigated (adenine, guanine, uracil and cytosine) influence the functioning of the isolated Helix hearts. On Anodonta hearts cytosine nucleotides proved themselves to be ineffective.
Pécsi, Tibor, S.-Rózsa, Katalin
core
Tautomerization‐assisted oxidation of molnupiravir by superoxide (O2•−) in aprotic DMF. The thermodynamically favored oxime tautomer of the N4‐hydroxycytosine moiety forms a prereactive complex (PRC) with O2•− through hydrogen‐bonding interactions.
Tatsushi Nakayama, Kaisei Hara
wiley +1 more source

