Results 131 to 140 of about 601,747 (289)
Plant Biotechnology Journal, EarlyView.ABSTRACT Base excision repair (BER) is a critical pathway for repairing damaged DNA bases in cells; however, the mechanisms of protein recruitment and interaction in this pathway remain largely unexplored in higher plants. In this study, we used ‘84K’ poplar (Populus alba × P.
Aoyu Ling +8 more
wiley +1 more source
Tiling Nussinov’s RNA folding loop nest with a space-time approach
BMC Bioinformatics, 2019 Background An RNA primary structure, or sequence, is a single strand considered as a chain of nucleotides from the alphabet AUGC (adenine, uracil, guanine, cytosine).
Marek Palkowski, Wlodzimierz Bielecki
doaj +1 more source
Brain Pathology, Volume 36, Issue 2, March 2026.Six new cases of intracranial mesenchymal tumors with FET::CREB fusion, alongside 20 previously reported cases underwent DNA methylation profiling uncovered a novel epigenetic subgroup distinguished by inferior PFS and unique clinicopathological, molecular, and epigenetic hallmarks.
Yong Lin +12 more
wiley +1 more source
Repair and DNA Polymerase Bypass of Clickable Pyrimidine Nucleotides
BiomoleculesClickable nucleosides, most often 5-ethynyl-2′-deoxyuridine (EtU), are widely used in studies of DNA replication in living cells and in DNA functionalization for bionanotechology applications.
Anton V. Endutkin +6 more
doaj +1 more source
ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae. [PDF]
, 1996 A K+ channel gene has been cloned from Drosophila melanogaster by complementation in Saccharomyces cerevisiae cells defective for K+ uptake. Naturally expressed in the neuromuscular tissues of adult flies, this gene confers K+ transport capacity on yeast
Goldstein, SA +3 more
core +1 more source
Crystal structure of a tRNA acceptor‐stem mimic at 1.94 Å resolution
Acta Crystallographica Section F, Volume 82, Issue 2, Page 57-65, February 2026.This paper reports the structure solution of an RNA complex using anomalous scattering.Despite the theoretical advantages of phosphorus single‐wavelength anomalous diffraction (P‐SAD) for nucleic acid phasing, its application remains limited due to high atomic displacement parameters and an unfavourable ratio of unique reflections to anomalous ...
Ziwei Liu +5 more
wiley +1 more source
Role of Arg243 and His239 Residues in the Recognition of Damaged Nucleotides by Human Uracil-DNA Glycosylase SMUG1 [PDF]
, 2020 Danila A. Iakovlev +3 more
openalex +1 more source
Human FASTK preferentially binds single‐stranded and G‐rich RNA
The FEBS Journal, Volume 293, Issue 3, Page 729-748, February 2026.Although FASTK is known to play a role in mRNA biology, the mechanism through which it recognizes RNA has yet to be unraveled. Here, we used purified human FASTK to characterize its RNA‐binding properties in vitro. We found that FASTK prefers ssRNA oligonucleotides containing guanines with the potential to form G‐quadruplexes and binds robustly to any ...
Daria M. Dawidziak +7 more
wiley +1 more source
BMC BiotechnologyThermostable DNA polymerases, such as Taq isolated from the thermophilic bacterium Thermus aquaticus, enable one-pot exponential DNA amplification known as polymerase chain reaction (PCR). However, properties other than thermostability - such as fidelity,
Cristina Hernández-Rollán +4 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.ABSTRACT Renal cell carcinoma (RCC) presents a significant global health challenge, with a substantial proportion of patients diagnosed with advanced or metastatic disease due to the limitations of current diagnostic imaging and the lack of validated non‐invasive biomarkers.
Hossam Kamli, Najeeb Ullah Khan
wiley +1 more source