Results 141 to 150 of about 601,747 (289)

Autism-associated SNPs in the clock genes _npas2_, _per1_ and the homeobox gene _en2_ alter DNA sequences that show characteristics of microRNA genes. [PDF]

, 2008
Intronic single nucleotide polymorphisms (SNPs) in the clock genes _npas2_ and _per1_ and the homeobox gene _en2_ are reported to be associated with autism.
Brad Nicholas, Dawn C. Wimpory, Michael J. Owen, Thomas Caspari   +3 more
core   +1 more source

Mechanical stimulation-induced purinome priming fosters osteogenic differentiation and osteointegration of mesenchymal stem cells from the bone marrow of post-menopausal women

Stem Cell Research & Therapy
Background Mechanical stimulation (MS) significantly increases the release of adenine and uracil nucleotides from bone marrow-derived mesenchymal stem cells (BM-MSCs) undergoing osteogenic differentiation.
Catarina Bessa-Andrês, Rui Pinto-Cardoso, Karyna Tarasova, Ana Luísa Pereira-Gonçalves, Joana Maria Gaio-Ferreira-Castro, Liliana S. Carvalho, Maria Adelina Costa, Fátima Ferreirinha, Ana Canadas-Sousa, José Marinhas, Rolando Freitas, Rui Lemos, Adélio Vilaça, António Oliveira, Paulo Correia-de-Sá, José Bernardo Noronha-Matos   +15 more
doaj   +1 more source

Organic Hazes as a Source of Life’s Building Blocks to Warm Little Ponds on the Hadean Earth

The Planetary Science Journal
Over 4 billion years ago, Earth is thought to have been a hazy world akin to Saturn’s moon Titan. The organic hazes in the atmosphere at this time could have contained a vast inventory of life’s building blocks and thus may have seeded warm little ponds ...
Ben K. D. Pearce, Sarah M. Hörst, Joshua A. Sebree, Chao He   +3 more
doaj   +1 more source

SARS-CoV-2 has observably higher propensity to accept uracil as nucleotide substitution: Prevalence of amino acid substitutions and their predicted functional implications in circulating SARS-CoV-2 in India up to July, 2020 [PDF]

, 2020
Subrata Roy, Himadri Nath, Abinash Mallick, Subhajit Biswas   +3 more
openalex   +1 more source

Synthesis and Structure−Activity Relationships of Uracil Nucleotide Derivatives and Analogues as Agonists at Human P2Y₂, P2Y₄, and P2Y₆Receptors

, 2006
Ali El‐Tayeb, Aidong Qi, Christa E. Müller   +2 more
openalex   +1 more source

Stimulation of uracil nucleotide synthesis in mouse liver, intestine and kidney by ammonium chloride infusion [PDF]

, 1988
Daniel Zaharevitz, Elizabeth Napier, Lawrence W. Anderson, John M. Strong, Richard L. Cysyk   +4 more
openalex   +1 more source

Comparison of the composition, immunological activity and anti-fatigue effects of different parts in sika deer antler

Frontiers in Pharmacology
BackgroundSika deer (Cervus nippon Temminck, 1838) antler is a highly esteemed tonic renowned for its abundant assortment of polypeptides, polysaccharides, amino acids, and minerals, and is recognized for its multifarious pharmacological properties ...
Siqi Chen, Yidan Li, Yichun Yang, Shibo Zhao, Huali Shi, Chengkai Yang, Min Wu, Aiwu Zhang   +7 more
doaj   +1 more source

Single-nucleotide polymorphisms of uracil-processing genes affect the occurrence and the onset of recurrent depressive disorder

, 2018
Piotr Czarny, Paulina Wigner, Justyna Strycharz, Cezary Watała, Ewa Świderska, Ewelina Synowiec, Piotr Gałecki, Monika Talarowska, Janusz Szemraj, Kuan‐Pin Su, Tomasz Śliwiński   +10 more
openalex   +1 more source

Patterns of DNMT1 Promoter Methylation in Patients with Acute Lymphoblastic Leukemia

International Journal of Hematology-Oncology and Stem Cell Research, 2016
Background: Acute lymphoblastic leukemia (ALL) is a clonal malignant disorder characterized by an uncontrolled proliferation of immature T or B lymphocytes.
Tirdad Rahmani, Mehdi Azad, Bahram Chahardouli, Hajar Nasiri, Mousa Vatanmakanian, Saeid Kaviani   +5 more
doaj  

Synthesis and structure–activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonists

, 2015
Diana Meltzer, Ophir Ethan, Guillaume Arguin, Yael Nadel, Ortal Danino, Joanna Lecka, Jean Sévigny, Fernand‐Pierre Gendron, Bilha Fischer   +8 more
openalex   +1 more source