Results 121 to 130 of about 151,121 (186)
Nutritional Factors Affecting Uremic Toxin Production
ToxinsChronic kidney disease (CKD) is characterized by persistent exposure to uremic toxins (UTs), many of which originate from gut microbial metabolism and contribute to renal, cardiovascular, and metabolic complications.
Fanny Jouve +2 more
doaj +1 more source
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.Treatment with empagliflozin or dapagliflozin was associated with a modest increase in plasma concentration of TMAO in Type 2 diabetes patients. These findings suggest a possible class effect of SGLT‐2 inhibitors. Whether this effect impacts the overall clinical benefits of SGLT‐2 inhibitors needs to be subject to further investigation.
Katja B. Zimmer +6 more
wiley +1 more source
Shiga Toxin-Associated Hemolytic Uremic Syndrome and Unexpected Course
Turkish Journal of Nephrology, 2019 Hemolytic uremic syndrome is a disease that often requires the transfusion of blood products. A child (two and a half years old, boy) with Shiga toxin-associated hemolytic uremic syndrome who developed respiratory distress after transfusion is presented.
Hakan ERDOĞAN +4 more
doaj
, 2018 International audience3-Carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) is a metabolite of furan fatty acid and a marker of fish oil intake. CMPF is described as a protein-bound uremic toxin and interacts with free oxygen radicals, which can induce ...
Szelag, Jean Christophe +23 more
core +1 more source
HemaSphere, Volume 10, Issue 11, November 2026.Abstract Advanced mycosis fungoides (MF) and Sézary syndrome (SS) are the most aggressive forms of cutaneous T‐cell lymphoma and remain associated with a poor prognosis and heterogeneous therapeutic approaches. Recent advances, including targeted therapies and improved transplant strategies, have substantially expanded treatment options, highlighting ...
Francesco Onida +29 more
wiley +1 more source
KLOTHO methylation is linked to uremic toxins and chronic kidney disease
, 2014 Epigenetic regulation plays a major role in uremic toxin-induced chronic kidney disease (CKD) progression. The KLOTHO protein is a key modulator of homeostasis in renal function.
Young, Guang-Huar;Wu, Vin-Cent +1 more
core +1 more source
Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies
MedComm, Volume 7, Issue 11, November 2026.Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang +4 more
wiley +1 more source
Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification
FEBS Open BioIntestinal disorders and vascular calcification (VC) are often associated with chronic kidney disease (CKD). While gut barrier alterations have been reported in CKD (such as abnormal intestinal permeability, bacterial overgrowth, and inflammation), it is
Piotr Bartochowski +13 more
doaj +1 more source
Liver Injury Repair and Regeneration: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 11, November 2026.This review outlines the spatiotemporal framework of liver injury repair and regeneration, orchestrated by molecular signaling, multicellular niche crosstalk, metabolic reprogramming, and interorgan communication. Post‑injury regenerative cascades (initiation, proliferation, termination) rely on crosstalk between hepatocytes, Kupffer cells, hepatic ...
Mingyue Pan +15 more
wiley +1 more source
The uremic toxin indoxyl sulfate reflects cardio-renal risk and intestinal-renal relationship
, 2011 Uremic syndrome and condition is primarily a result of kidney failure in which uremic toxins are accumulated. More and more attention is paid to possibilities for removal of uremic toxins, which not only means dialysis, but also takes into account ...
István Kiss
core +1 more source