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Nondialyzable Uremic Toxins

Blood Purification, 2013
Nondialyzable uremic toxins can be defined as solutes producing adverse biological effects that consequently to peculiar physicochemical features (mainly their large size and hydrophobic character) cannot leave the blood stream through a dialysis membrane.
PIRODDI, MARTA   +3 more
openaire   +2 more sources

Uremic toxins.

Kidney international. Supplement, 1988
It is the purpose of this paper to review our present knowledge about uremic toxicity, with a special emphasis on the methods that have been used to try to resolve this problem. More and more, sophisticated methods become available for the study of uremic toxicity.
Ringoir, S.M.G.   +2 more
openaire   +2 more sources

An update on uremic toxins

International Urology and Nephrology, 2012
In the last decade, uremic toxicity as a potential cause for the excess of cardiovascular disease and mortality observed in chronic kidney disease gained more and more interest. This review focuses on uremic toxins with known cardiovascular effects and their removal. For protein-bound solutes, for example, indoxylsulfate and the conjugates of p-cresol,
N, Neirynck   +5 more
openaire   +2 more sources

Aluminum an Uremic Toxin

1987
Aluminum has historically been regarded as non essential, since up to now no physiological function could be ascribed to it. Environmental exposure to aluminum is virtually universal as aluminum constitutes a substantial part of the earth’s crust (8%) and is found in food, medicine and cosmetics.
P C, D'Haese   +3 more
openaire   +2 more sources

Uremic Toxins and Oral Adsorbents

Therapeutic Apheresis and Dialysis, 2011
AbstractUremic toxins are associated with various disorders in patients with end‐stage renal disease and it is difficult to remove some of these toxins by dialysis. Since some uremic toxins are generated by bacterial metabolites in the colon, oral adsorbents that interfere with the absorption of uremic toxins or their precursors are believed to prevent
Shunsuke, Goto   +4 more
openaire   +2 more sources

Uremic toxin and bone metabolism

Journal of Bone and Mineral Metabolism, 2006
Patients with end-stage renal disease (ESRD) develop various kinds of abnormalities in bone and mineral metabolism, widely known as renal osteodystrophy (ROD). Although the pathogenesis of ESRD may be similar in many patients, the response of the bone varies widely, ranging from high to low turnover.
Yoshiko, Iwasaki   +7 more
openaire   +2 more sources

Adipokines as Uremic Toxins

Journal of Renal Nutrition, 2012
The adipose tissue has pleiotropic functions far beyond the mere storage of energy, and it secretes a number of hormones and cytokines, called adipokines, which have biological effects that impact heath and disease. Adipokines are markedly elevated in the plasma of uremic patients, mainly due to decreased renal excretion.
openaire   +2 more sources

PROGRESS IN UREMIC TOXIN RESEARCH: Parathyroid Hormone, A Uremic Toxin

Seminars in Dialysis, 2009
AbstractDespite the innovations in the treatment of secondary hyperparathyroidism, there are uremic patients with marked elevation in PTH levels. Uremic toxicity is in part attributable to the excess of circulating PTH. It has been known for many years that PTH may induce changes in cell calcium, a key intracellular signal required for normal cell ...
Mariano Rodriguez, Victor Lorenzo
openaire   +1 more source

Low water-soluble uremic toxins

Advances in Renal Replacement Therapy, 2003
The uremic syndrome is the result of the retention of solutes, which under normal conditions are cleared by the healthy kidneys. Uremic retention products are arbitrarily subdivided according to their molecular weight. Low-molecular-weight molecules are characterized by a molecular weight below 500 D. The purpose of the present publication is to review
Vanholder, Raymond Camille   +3 more
openaire   +3 more sources

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