Results 191 to 200 of about 2,782,099 (278)

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

ChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

Cinnamaldehyde Attenuates Hyperuricemia-Associated Renal Injury by Modulating Urate Transporters and AIF1- and CMPK2/NLRP3-Related Inflammatory Signaling. [PDF]

Pharmaceuticals (Basel)
Sun Y, Tan H, Zhang J, Zhang Z, Huai S, Wang M.   +5 more
europepmc   +1 more source

Interactive Effects of Dietary Crude Protein and Methionine Levels on Growth Performance, Carcass Quality and Blood Biochemistry of Japanese Quail During Starter and Grower Phases

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Dietary crude protein and methionine interact significantly in Japanese quail. Optimal methionine ranges from 0.50%–0.70% depending on protein level and phase. Best grower performance occurs at 25% CP with 1.30% Met, yielding 161.84 g male weight gain. Females show superior breast yield (30.90%).
Elyas Piroz‐Maleki, Mehdi Taginejad‐Rodbaneh, Ruhollah Kianfar, Sima Moghaddaszadeh‐Ahrabi, Abolfazl Ghorbani   +4 more
wiley   +1 more source

Accelerating Phosphate Transport Across Membranes via Synergistic Chemical‐Electrochemical Carriers

Angewandte Chemie, Volume 138, Issue 43, 19 October 2026.
A new membrane design principle based on synergistic chemical and electrochemical carriers is proposed to construct an electro‐driven carrier‐conducting membrane for high‐throughput phosphate transport. Monodispersed ferrihydrite nanoparticles embedded within the membrane act as built‐in phosphate carriers, enabling accelerated phosphate migration via ...
Lei Xia, Yangbo Qiu, Qingzhi Liu, Mengjiao Guan, Xi Zhang, Raf Dewil, Jin Shang, Yan Zhao, Bart Van der Bruggen, Chuyang Tang   +9 more
wiley   +2 more sources

Resveratrol Ameliorates Hyperuricemia in Association with Remodeling of the Gut Microbiota-Metabolism Axis: An Integrated 16S rDNA Sequencing and Fecal Metabolomics Study. [PDF]

Foods
Wang Y, Xie J, Cao Z, Gao X, Yang Z, Tian Y, Sheng J, Peng L.   +7 more
europepmc   +1 more source

Reprogramming Native Cryptic Plasmids Enables Antibiotic‐Selection‐Free Urate Degradation by Escherichia coli Nissle 1917

Microbial Biotechnology, Volume 19, Issue 11, November 2026.
Reprogramming native cryptic plasmids of Escherichia coli Nissle 1917 enabled antibiotic‐selection‐free and oxygen‐adaptive urate degradation. The engineered strain reduced uric acid levels and alleviated hyperuricemia‐associated renal and inflammatory abnormalities in mice, supporting endogenous plasmid engineering as a strategy for live ...
Yuan Chi, Shiying Wu, Fei Lin, Tingwen Fan, Hongwei Liu, Huaiyi Yang   +5 more
wiley   +1 more source

Drug-induced hyperuricemia: multi-pathway regulation, causative drugs, and individualized management strategies. [PDF]

Front Pharmacol
Xiong B, Duan C, Xu S, Xu S, Yang C, He D, Luo C.   +6 more
europepmc   +1 more source

Systematic Comparison of High‐Fat Diet– and Streptozotocin‐Induced Prediabetic Obese C57BL/6J Mouse Models: A Sex‐Based Protocol Optimization Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9897-9918, November 2026.
ABSTRACT Aims Animal models of prediabetes (Pre‐DM) are essential for studying metabolic disease and testing therapies, yet high‐fat diet (HFD) and HFD‐plus‐streptozotocin (STZ) protocols vary in feeding duration, STZ dose, and diagnostic criteria and rarely account for sex.
Min Xu, Chao Ke, Yangkun Liu, Wenying Shi, Yang Cao, Zhengyu Li, Yi Xiao, Wei Zhang   +7 more
wiley   +1 more source

6'‑O‑Caffeoylarbutin attenuates experimental hyperuricemia by regulating renal and intestinal urate transport, intestinal barrier integrity, and gut microbiota. [PDF]

Mol Med Rep
Yu X, Zhang Y, Sun K, Yang R, Li X, Chen X, Li T, Yang X, Li M, Liu L, Li F, Shen B.   +11 more
europepmc   +1 more source

Oleanolic Acid‐Enriched Olive Oil Attenuates Kidney Function Decline in Patients With Type 2 Diabetes: Results From the OLTRAD Randomised Controlled Trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10195-10209, November 2026.
ABSTRACT Aims Chronic kidney disease (CKD) is a major complication of type 2 diabetes mellitus (T2DM), driven in part by oxidative stress and the accumulation of advanced glycation end products (AGEs). Oleanolic acid (OA), a natural triterpene present in olive‐derived matrices, may modulate AGE metabolism.
Aída García‐González, Alejandro Matamoros‐Domínguez, Juan Manuel Espinosa‐Cabello, Gisela Pérez‐Muñoz, Manuel Jesús León Aranda, María Del Carmen Roque‐Cuellar, Silvia García‐Rey, Andrés Jiménez‐Sánchez, Antonio Jesús Martínez‐Ortega, Miguel Ángel Mangas‐Cruz, Isabel Cerrillo, Javier S. Perona, Pedro Pablo García‐Luna, Elena María Yubero‐Serrano, José María Castellano   +14 more
wiley   +1 more source