Results 201 to 210 of about 2,782,099 (278)

Therapeutic potential of traditional Chinese medicine for hyperuricemia: mechanistic insights and clinical prospects. [PDF]

Front Pharmacol
Li H, You S, Luo X, Huang Y, Li M, Zhou J, Ren S.   +6 more
europepmc   +1 more source

Novel Amino Acid Changes Increase Phosphoenolpyruvate Carboxylase Output in planta

Plant, Cell &Environment, Volume 49, Issue 11, Page 8306-8321, November 2026.
ABSTRACT Characterization of previously reported Arabidopsis mutants with increased aluminum (Al) resistance (alr) resulting from greater release of Al‐chelating malate identified three unique amino acid substitutions that each impacts PHOSPHOENOLPYRUVATE CARBOXYLASE 1, a key anaplerotic carbon fixation enzyme.
Jinrui Sheng, Kevin Frausto, Sarah Haesaerts, Taylor J. Meyer, Maruša Prolič‐Kalinšek, Seán E. O'Leary, Remy Loris, Paul B. Larsen   +7 more
wiley   +1 more source

Multi-omics insights into uric acid metabolism in cardiometabolic disease: from genetics to metabolomics. [PDF]

Biomed J
Ali N.
europepmc   +1 more source

The role of gut microbiota dysbiosis in the pathogenesis of hyperuricemic nephropathy. [PDF]

Front Mol Biosci
Jiang Q, Zhu X, Yin L.
europepmc   +1 more source

Association of Neutrophil Percentage‐to‐Albumin Ratio (NPAR) With Pathological Features and Long‐Term Prognosis in Diabetic Kidney Disease: A Cohort Study

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
This graphical abstract summarizes the association between the neutrophil percentage‐to‐albumin ratio (NPAR), renal pathology, and prognosis in biopsy‐confirmed diabetic kidney disease. Higher NPAR was associated with increased renal MPO‐positive neutrophil infiltration, more severe histopathological injury, and poorer renal outcomes.
Yang Li, Hongyu Wang, Wendi He, Yi Fang, Shi Jin, Hong Liu, Jie Li, Nana Song, Xiaoqiang Ding, Yan Dai   +9 more
wiley   +1 more source

Pomegranate Peel Polyphenol Extract Ameliorates Hyperuricemia by Inhibiting Uric Acid Synthesis and Reabsorption. [PDF]

Chem Biol Drug Des
Yin Z, Liang S, Yang G, Guo P, Wang C, Han Q, Song X.   +6 more
europepmc   +1 more source

One Hundred Years of Sulfido Ligand in the Molybdenum Cofactor: New Perspectives

ChemBioChem, Volume 27, Issue 19, 14 October 2026.
The terminal sulfido ligand in mononuclear molybdoenzymes has been appreciated for almost 125 years, with the characterization of Schardinger's enzyme in cow's milk, now known to be xanthine oxidase, that was isolated in 1902 in Vienna, Austria. The ligand is found in molybdoenzymes identified across all kingdoms of life.
Silke Leimkühler, Benjamin R. Duffus, Carola Schulzke   +2 more
wiley   +1 more source

Therapy-Persistent Leukemia Is Selectively Vulnerable to SLC23A1 Restoration via Targeting KHSRP. [PDF]

Blood Cancer Discov
Luo Q, Whalen KS, Wu X, Fortune AL, Garcia JS, Marinchev K, Zhang L, Qian W, Raulston EG, Nan Y, Booth CAG, Yan K, Root DE, Doench JG, Lane AA.   +14 more
europepmc   +1 more source

Comprehensive phytochemical profiling of dealcoholized zhuyeqing liquor extract and its protective effect on hyperuricemia by regulating urate transporters and LPS/NLRP3 inflammasome pathway. [PDF]

Front Nutr
Xu B, Li X, Liu R, Han Y, Zhen P, Fu H, Lv H, Wei F, Cui H, Zhang B, Wang S.   +10 more
europepmc   +1 more source

<i>Camellia oleifera</i> Seed Cake Extract Ameliorates Hyperuricemia and Renal Injury by Modulating Uric Acid Metabolism, Nrf2/Keap1 Pathway, and NLRP3 Inflammasome in Mice. [PDF]

Food Sci Nutr
Mai L, Xie Y, Zhang Y, Ni C, Xu Y, Xu L, Lin G, Lin Y, Su Z, Wang J, Ren M.   +10 more
europepmc   +1 more source