Results 11 to 20 of about 98,911 (236)
Uridine affects liver protein glycosylation, insulin signaling, and heme biosynthesis. [PDF]
PLoS ONE, 2014 Purines and pyrimidines are complementary bases of the genetic code. The roles of purines and their derivatives in cellular signal transduction and energy metabolism are well-known.
Yasuyo Urasaki +2 more
doaj +2 more sources
Uridine Diphosphoacetylglucosamine Pyrophosphorylase
Journal of Biological Chemistry, 1959 Jack L. Strominger, Mildred S. Smith
openalex +4 more sources
Protocol for UVC uridine actinometry
MethodsX, 2023 Uridine contains the chromophore uracil, a base forming part of RNA. In the range 240–290 nm, the absorption spectra of uridine and DNA are very similar and correspond to the spectral inactivation sensitivity of almost all microorganisms.
Dana Pousty +3 more
doaj +3 more sources
The Preparation of Uridine Diphosphoacetylgalactosamine [PDF]
Journal of Biological Chemistry, 1959 Jack L. Strominger, Mildred S. Smith
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Uridine-derived ribose fuels glucose-restricted pancreatic cancer
Nature, 2023 A metabolite screen of pancreatic cells shows that pancreatic cancer cells metabolize uridine-derived ribose via UPP1, supporting redox balance, survival and proliferation.
Z. Nwosu +28 more
semanticscholar +1 more source
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage
International Journal of Molecular Sciences, 2023 Uridine metabolism is extensively reported to be involved in combating oxidative stress. Redox-imbalance-mediated ferroptosis plays a pivotal role in sepsis-induced acute lung injury (ALI).
Kai Lai +6 more
semanticscholar +1 more source
A Treatable Genetic Disease Caused by CAD Mutation
Frontiers in Pediatrics, 2022 Type 50 early infantile epileptic encephalopathy, or EIEE-50 for short, is an autosomal recessive genetic disorder resulting from CAD mutations. So far, little has been reported on the disease.
Xia Peng +8 more
doaj +1 more source
Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions
Nature Metabolism, 2023 Glucose is vital for life, serving as both a source of energy and carbon building block for growth. When glucose is limiting, alternative nutrients must be harnessed.
Owen S. Skinner +11 more
semanticscholar +1 more source
Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor
Cell Discovery, 2022 Regenerative capacity declines throughout evolution and with age. In this study, we asked whether metabolic programs underlying regenerative capability might be conserved across species, and if so, whether such metabolic drivers might be harnessed to ...
Zunpeng Liu +26 more
semanticscholar +1 more source
Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2
Communications Biology, 2021 SARS-CoV-2 Nsp15 is a uridine-specific endoribonuclease with C-terminal catalytic domain belonging to the EndoU family that is highly conserved in coronaviruses.
Youngchang Kim +10 more
semanticscholar +1 more source