Results 11 to 20 of about 73,683 (226)

Lactobacillus plantarum Ameliorates High-Carbohydrate Diet-Induced Hepatic Lipid Accumulation and Oxidative Stress by Upregulating Uridine Synthesis

open access: yesAntioxidants, 2022
The overconsumption of carbohydrates induces oxidative stress and lipid accumulation in the liver, which can be alleviated by modulation of intestinal microbiota; however, the underlying mechanism remains unclear.
Rong Xu   +7 more
doaj   +1 more source

A Treatable Genetic Disease Caused by CAD Mutation

open access: yesFrontiers in Pediatrics, 2022
Type 50 early infantile epileptic encephalopathy, or EIEE-50 for short, is an autosomal recessive genetic disorder resulting from CAD mutations. So far, little has been reported on the disease.
Xia Peng   +8 more
doaj   +1 more source

Uridine treatment protects against blood-brain barrier disruption in a rat model of Li-pilocarpine-induced status epilepticus. [PDF]

open access: yesFront Neurosci
IntroductionBlood–brain barrier (BBB) disruption is one of the most striking changes triggered by status epilepticus, which deserves specific attention in terms of novel treatment approaches targeting epileptogenesis.
Aydin B   +6 more
europepmc   +2 more sources

Dietary uridine improves lipid homeostasis in high-fat diet-induced obese mice by regulating liver gene expression and metabolomic profiles. [PDF]

open access: yesFront Nutr
IntroductionObesity is caused by excessive storage of adipose tissue and leads to metabolic disorders. Uridine exerts modulatory effects on lipid metabolism, but the regulatory mechanism in obesity needs further research.MethodsIn this study, the effects
Liu Y, Zhang H, Yang X, Xie C.
europepmc   +2 more sources

LDL cholesterol and uridine levels in blood are potential nutritional biomarkers for clinical progression in Alzheimer's disease: The NUDAD project

open access: yesAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020
INTRODUCTION We examined associations between nutritional biomarkers and clinical progression in individuals with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's disease (AD)‐type dementia.
Francisca A. deLeeuw   +14 more
doaj   +1 more source

Honey as Source of Nitrogen Compounds: Aromatic Amino Acids, Free Nucleosides and Their Derivatives

open access: yesMolecules, 2020
The content of selected major nitrogen compounds including nucleosides and their derivatives was evaluated in 75 samples of seven varieties of honey (heather, buckwheat, black locust, goldenrod, canola, fir, linden) by targeted ultra-high performance ...
Piotr M. Kuś
doaj   +1 more source

SYNTHESIS A NUMBER OF URIDINE DERIVATIVES AND STUDYING THEIR BIOLOGICAL ACTIVITY ON PATHOGENIC BACTERIA. [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
یتضمن البحث تحضیر سلسلة من المرکبات بطریقة ازدواج املاح الدیازونیوم مع الیوردین. وتم التأکد من الصیغ الترکیبیة للمرکبات المحضرة بدراسة اطیاف الاشعة فوق البنفسجیة (U.V) واطیاف الاشعة تحت الحمراء(I.R) والتحلیل الدقیق لعناصر الکاربون، الهیدروجین والنتروجین (
YOUSIF HINDY KHALAF, SALMAN ALI AHMED
doaj   +1 more source

The Role of Uridine in Health and Disease. [PDF]

open access: yesJ Inflamm Res
Congkuan Song,1– 3 Zhen-Juan Liu,4 Bangjun Xu,5 Rui Zou,1,2 Weidong Hu1– 3 1Department of Thoracic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, People’s Republic of China; 2Hubei Provincial Clinical Research Center for Cancer, Wuhan, People’s ...
Song C, Liu ZJ, Xu B, Zou R, Hu W.
europepmc   +2 more sources

Development of Diversified Methods for Chemical Modification of the 5,6-Double Bond of Uracil Derivatives Depending on Active Methylene Compounds

open access: yesMolecules, 2012
The reaction of 5-halogenouracil and uridine derivatives <strong>1</strong> and <strong>7</strong> with active methylene compounds under basic conditions produced diverse and selective C-C bond formation products by virtue of the ...
Kosaku Hirota   +8 more
doaj   +1 more source

Uridine metabolism in HIV-1-infected patients: effect of infection, of antiretroviral therapy and of HIV-1/ART-associated lipodystrophy syndrome. [PDF]

open access: yesPLoS ONE, 2010
BackgroundUridine has been advocated for the treatment of HIV-1/HAART-associated lipodystrophy (HALS), although its metabolism in HIV-1-infected patients is poorly understood.MethodsPlasma uridine concentrations were measured in 35 controls and 221 HIV-1-
Pere Domingo   +14 more
doaj   +1 more source

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