Pharmacoepidemiology and Drug Safety, Volume 34, Issue 6, June 2025.ABSTRACT Background Ceftriaxone is believed to increase the risk of biliary infections due to pseudolithiasis caused by ceftriaxone‐calcium precipitation, but this risk is not well understood. This study aimed to investigate whether ceftriaxone use is associated with an increased risk of biliary infections in pneumonia patients using a national ...
Jumpei Taniguchi +4 more
wiley +1 more source
Management of Drug Interactions with Inducers: Onset and Disappearance of Induction on Cytochrome P450 3A4 and Uridine Diphosphate Glucuronosyltransferase 1A1 Substrates. [PDF]
Eur J Drug Metab Pharmacokinet, 2023 Bettonte S +4 more
europepmc +1 more source
Protein Science, Volume 34, Issue 6, June 2025.Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Spyros D. Chatziefthymiou +13 more
wiley +1 more source
Cell-Free Multi-Enzyme Synthesis and Purification of Uridine Diphosphate Galactose. [PDF]
Chembiochem, 2022 Mahour R +8 more
europepmc +1 more source
Bacterial purine metabolism modulates C. elegans development and stress tolerance via DAF‐16
The FEBS Journal, Volume 292, Issue 11, Page 2771-2783, June 2025.Purine metabolism is crucial for cellular function and is a conserved metabolic network from prokaryotes to humans, but remains poorly understood in metazoan. To investigate the impact of dietary components on purine metabolism and animal growth, we screened the effects of an Escherichia coli single‐gene deletion library on the growth of the nematode ...
Min Feng +3 more
wiley +1 more source
Effect of the genetic mutant G71R in uridine diphosphate-glucuronosyltransferase 1A1 on the conjugation of bilirubin. [PDF]
Open Life Sci, 2022 Chen H, Zhong D, Gao Z, Wu X.
europepmc +1 more source
New Phytologist, Volume 246, Issue 5, Page 2102-2117, June 2025.Summary Photorespiration is a mandatory metabolic repair shunt of carbon fixation by the Calvin–Benson cycle in oxygenic phototrophs. Its extent depends mainly on the CO2 : O2 ratio in chloroplasts, which is regulated via stomatal movements. Despite a comprehensive understanding of the role of photorespiration in mesophyll cells, its role in guard ...
Hu Sun +4 more
wiley +1 more source
The Genetics of Glucose-6-Phosphate-Dehydrogenase (G6PD) and Uridine Diphosphate Glucuronosyl Transferase 1A1 (UGT1A1) Promoter Gene Polymorphism in Relation to Quantitative Biochemical G6PD Activity Measurement and Neonatal Hyperbilirubinemia. [PDF]
Children (Basel), 2023 Riskin A +7 more
europepmc +1 more source
Plant Biotechnology Journal, Volume 23, Issue 6, Page 2018-2033, June 2025.Summary Plant‐specific WUSCHEL‐related homeobox (Wox) transcription factors (TFs) are crucial for plant growth and development. However, the molecular mechanism of Wox‐mediated regulation of thousand kernel weight (TKW) in crops remains elusive. In this research, we identified a major TKW‐associated quantitative trait locus (QTL) on wheat chromosome ...
Hongxia Liu +10 more
wiley +1 more source
Glucosylation of (±)-Menthol by Uridine-Diphosphate-Sugar Dependent Glucosyltransferases from Plants. [PDF]
Molecules, 2021 Kurze E +8 more
europepmc +1 more source