Results 111 to 120 of about 29,456 (288)

Morin as a Modulator of Hepatic Glucose Fluxes: A Balance Between Antihyperglycemic Potential and Mitochondrial Toxicity

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 39, Issue 7, July 2025.
Morin modulates hepatic glucose metabolism by inhibiting gluconeogenesis and enhancing glycogenolysis in perfused rat livers. These effects, partly attributed to mitochondrial dysfunction and impaired oxidative phosphorylation, are accompanied by decreased ATP levels and enzyme inhibition, raising concerns about bioenergetic imbalance and potential ...
Letícia Fernanda Nanami   +19 more
wiley   +1 more source

Urinary Recovery of Salicylamide as Its Glucuronide in Liver Disease [PDF]

open access: yes, 1962
An attempt was made to establish the method for the estimation of glucuronide formation in vivo using salicylamide and further to study the alteration in the glucuronide formation in liver disease. The results were as follows: 1.
Taketa, Kazuhisa
core   +1 more source

CRISPR/Cas9-Based Functional Characterization of SfUGT50A15 Reveals Its Roles in the Resistance of Spodoptera frugiperda to Chlorantraniliprole, Emamectin Benzoate, and Benzoxazinoids

open access: yesInsects
UDP-glycosyltransferases (UGTs) are a diverse superfamily of enzymes. Insects utilize uridine diphosphate-glucose (UDP-glucose) as a glycosyl donor for glycosylation in vivo, involved in the glycosylation of lipophilic endosymbionts and xenobiotics ...
Zhan Shi   +5 more
doaj   +1 more source

Effects of galU Mutation on Pseudomonas syringae–Plant Interactions

open access: yesMolecular Plant-Microbe Interactions, 2010
Bacterial galU coding for a uridine diphosphate-glucose pyrophosphorylase plays an important role in carbohydrates biosynthesis, including synthesis of lipopolysaccharides (LPS), membrane-derived oligosaccharides, and capsular polysaccharides.
Wen-Ling Deng   +6 more
doaj   +1 more source

Platelet Hyaluronan Synthase 3 Regulates Thrombin Signaling and Adhesion to Fibrinogen Under Venous Shear

open access: yesProteoglycan Research, Volume 3, Issue 3, July 2025.
ABSTRACT Hyaluronan (HA) is an essential glycosaminoglycan with supportive roles in hematopoiesis. HA is synthesized by hyaluronan synthases (HAS1, HAS2, and HAS3) and plays a crucial role in cellular signaling and extracellular matrix interactions.
Kimberly A. Queisser   +5 more
wiley   +1 more source

O-GlcNAc transferase in astrocytes modulates depression-related stress susceptibility through glutamatergic synaptic transmission

open access: yesThe Journal of Clinical Investigation, 2023
Major depressive disorder is a common and devastating psychiatric disease, and the prevalence and burden are substantially increasing worldwide. Multiple studies of depression patients have implicated glucose metabolic dysfunction in the pathophysiology ...
Jun Fan   +16 more
doaj   +1 more source

Arabinokinase Limits the Flux of Arabinose Into Nucleotide Sugars to Prevent Toxicity

open access: yesPlant Direct, Volume 9, Issue 7, July 2025.
ABSTRACT Arabinokinase (ARA1) is a key player in the recycling pathway of the major cell wall component L‐arabinose (L‐Ara). The enzyme catalyzes phosphorylation of L‐Ara to L‐arabinose‐1‐phosphate, which is then converted into UDP‐L‐arabinopyranose (UDP‐L‐Arap) by UDP‐sugar pyrophosphorylase (USP) followed by conversion into UDP‐L‐arabinofuranose (UDP‐
Eva Ivanov Kavkova   +6 more
wiley   +1 more source

P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents [PDF]

open access: yes, 1998
The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Barnard, EA   +3 more
core  

Defects in bile pigment metabolism causing jaundice [PDF]

open access: yes, 1961
The excretion of bilirubin and therefore the relief of jaundice is dependent upon at least three factors. First, the bilirubin must be conjugated and thus converted into a water soluble compound: this means its conversion to an ester glucuronide although
Billing, Barbara H.
core   +1 more source

Mulching with plastic film improved the root quality of summer-sown sweet potato (Ipomoea batatas (L). Lam.) in northern China

open access: yesJournal of Integrative Agriculture, 2019
The root quality of sweet potato cultivated during the summer season is poor in northern China; thus, this study was conducted to determine whether root quality could be improved through mulching with plastic film (MPF).
Fu-yun HOU   +5 more
doaj  

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