Results 111 to 120 of about 21,550 (284)

Simultaneous Monitoring of Tyrosinase and ATP in Thick Brain Tissues Using a Single Two‐Photon Fluorescent Probe

open access: yesAdvanced Science, Volume 12, Issue 19, May 22, 2025.
A single dual‐emission two‐photon fluorescent probe is designed for simultaneously tracking tyrosinase (TYR) and adenosine triphosphate (ATP). With the help of this probe, the intricate correlation and regulatory mechanism between TYR and ATP during oxidative stress is uncovered.
Hong Huang   +12 more
wiley   +1 more source

Characterisation of Optimal Responses to Pulse Inputs in the Bergman Minimal Model [PDF]

open access: yesarXiv, 2017
The Bergman minimal model is a dynamic model of plasma glucose concentration. It has two input variables -- insulin delivery and carbohydrate intake. We investigate the behaviour of plasma glucose concentration predicted by the model given carbohydrate (CHO) inputs and commensurate insulin inputs.
arxiv  

One‐Pot Hetero‐Di‐C‐Glycosylation of the Natural Polyphenol Phloretin by a Single C‐Glycosyltransferase With Broad Sugar Substrate Specificity

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 5, Page 1296-1304, May 2025.
Here, an efficient system for synthesizing high‐value polyphenol hetero‐di‐C‐glycosides with two distinct C‐glycosyl residues was established using a two‐step glycosylation catalyzed by C‐glycosyltransferase in one pot. The desired C‐β‐galactosyl‐C‐β‐glucosyl and C‐β‐glucosyl‐C‐β‐xylosyl phloretin were obtained at concentrations of 0.6 and 6 g/L ...
Tuo Li   +4 more
wiley   +1 more source

CRISPR/Cas9-Based Functional Characterization of SfUGT50A15 Reveals Its Roles in the Resistance of Spodoptera frugiperda to Chlorantraniliprole, Emamectin Benzoate, and Benzoxazinoids

open access: yesInsects
UDP-glycosyltransferases (UGTs) are a diverse superfamily of enzymes. Insects utilize uridine diphosphate-glucose (UDP-glucose) as a glycosyl donor for glycosylation in vivo, involved in the glycosylation of lipophilic endosymbionts and xenobiotics ...
Zhan Shi   +5 more
doaj   +1 more source

Effects of galU Mutation on Pseudomonas syringae–Plant Interactions

open access: yesMolecular Plant-Microbe Interactions, 2010
Bacterial galU coding for a uridine diphosphate-glucose pyrophosphorylase plays an important role in carbohydrates biosynthesis, including synthesis of lipopolysaccharides (LPS), membrane-derived oligosaccharides, and capsular polysaccharides.
Wen-Ling Deng   +6 more
doaj   +1 more source

Scalable, Non-Invasive Glucose Sensor Based on Boronic Acid Functionalized Carbon Nanotube Transistors [PDF]

open access: yes, 2013
We developed a scalable, label-free all-electronic sensor for D-glucose based on a carbon nanotube transistor functionalized with pyrene-1-boronic acid. This sensor responds to glucose in the range 1 uM - 100 mM, which includes typical glucose concentrations in human blood and saliva.
arxiv   +1 more source

P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents [PDF]

open access: yes, 1998
The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Barnard, EA   +3 more
core  

Metabolic profiling reveals coordinated switches in primary carbohydrate metabolism in grape berry (Vitis vinifera L.), a non-climacteric fleshy fruit [PDF]

open access: yes, 2013
Changes in carbohydrate metabolism during grape berry development play a central role in shaping the final composition of the fruit. The present work aimed to identify metabolic switches during grape development and to provide insights into the timing of
Dai, Z.   +5 more
core   +2 more sources

Targeting Triple‐Negative Breast Cancer: Resistance Mechanisms and Therapeutic Advancements

open access: yesCancer Medicine, Volume 14, Issue 9, May 2025.
ABSTRACT Background Triple‐negative breast cancer (TNBC) is one of the most heterogeneous and menacing forms of breast cancer, with no sustainable cure available in the current treatment landscape. Its lack of targets makes it highly unresponsive to various treatment modalities, which is why chemotherapy continues to be the primary form of treatment ...
Rachana Raman   +3 more
wiley   +1 more source

O-GlcNAc transferase in astrocytes modulates depression-related stress susceptibility through glutamatergic synaptic transmission

open access: yesThe Journal of Clinical Investigation, 2023
Major depressive disorder is a common and devastating psychiatric disease, and the prevalence and burden are substantially increasing worldwide. Multiple studies of depression patients have implicated glucose metabolic dysfunction in the pathophysiology ...
Jun Fan   +16 more
doaj   +1 more source

Home - About - Disclaimer - Privacy