Results 91 to 100 of about 7,719 (211)
Gut microbiome‐derived metabolites show promise in cancer research and therapy
Interdisciplinary Medicine, Volume 4, Issue 2, March 2026.The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang +4 more
wiley +1 more source
Expression and molecular characterization of an intriguing hyaluronan synthase (HAS) from the symbiont “Candidatus Mycoplasma liparidae” in snailfish [PDF]
PeerJBackground Hyaluronan synthases (HASs) are ubiquitous in living organisms, and the hyaluronic acid (HA) synthesized by them are important to their body and well used in medicine, cosmetics and other fields.
Lulu Guo +3 more
doaj +2 more sources
Characteristics of Group A Streptococcal Variants Treated with Mitomycin C [PDF]
Japanese Journal of Microbiology, 1973 ABSTRACTTransfers of Streptococcus pyogenes strain T12 in Todd–Hewitt broth containing stepwise increases in amounts of mitomycin C (MC) gave rise to slight changes of their colonial appearances. Variants thus obtained were examined for antibiotic and bile resistances; production of streptolysin‐S, ‐O and deoxyribonuclease; growth in alkaline medium ...
T, Hirano +3 more
openaire +2 more sources
Advanced Science, Volume 13, Issue 12, 27 February 2026.Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han +16 more
wiley +1 more source
Saccharomyces cerevisiae as a Host for Chondroitin Production
SynBioChondroitin is a glycosaminoglycan that has gained widespread use in nutraceuticals and pharmaceuticals, mainly for treating osteoarthritis. Traditionally, it has been extracted from animal cartilage but recently, biotechnological processes have emerged ...
Márcia R. Couto +3 more
doaj +1 more source
Role of N-glycosylation in oral cancer [PDF]
, 2017 Oral squamous cell carcinoma represents more than 90% head and neck cancers with high incidence rate and morbidity. To date, little is known about the molecular mechanisms responsible for OSCC initiation and progression to advanced disease.
Bukhari, Samah
core
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs [PDF]
, 2019 O-Linked α-N-acetylgalactosamine (O-GalNAc) glycans constitute a major part of the human glycome. They are difficult to study because of the complex interplay of 20 distinct glycosyltransferase isoenzymes that initiate this form of glycosylation, the ...
Bertozzi, Carolyn R. +9 more
core +3 more sources
Biotechnology and Applied Biochemistry, Volume 73, Issue 1, Page 43-55, February 2026.ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley +1 more source
iScience, 2018 Summary: We apply stable isotope tracing, mass-spectrometry-based untargeted metabolomics, to reveal the biochemical space labeled by 13C-substrates in bone-marrow-derived macrophages. At the pathway level, classically (lipopolysaccharide [LPS]-polarized,
Patrycja Puchalska +5 more
doaj +1 more source
Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms [PDF]
, 2016 Hyaluronic acid, or HA, is a rigid and linear biopolymer belonging to the class of the glycosaminoglycans, and composed of repeating units of the monosaccharides glucuronic acid and N-acetylglucosamine.
Carvalho, Lucas Silva +5 more
core +2 more sources