Results 1 to 10 of about 4,445 (126)

YvcK, a protein required for cell wall integrity and optimal carbon source utilization, binds uridine diphosphate-sugars. [PDF]

Sci Rep, 2017
In Bacillus subtilis, Listeria monocytogenes and in two Mycobacteria, it was previously shown that yvcK is a gene required for normal cell shape, for optimal carbon source utilization and for virulence of pathogenic bacteria.
Foulquier E, Galinier A.
europepmc   +4 more sources

UDP-glucose and MRS2905 agonist-bound states of the purinergic P2Y₁₄ receptor. [PDF]

Commun Biol
P2Y14 receptors respond to uracil-diphosphate-hexose conjugates, yet how this receptor selectively recognizes both uracil-nucleotides and hexose moieties of diverse agonists remains unclear.
Fay JF, Kousouros J, Gao ZG, Pavan M, Oliva P, Pramanik A, Meyer C, Kurma SH, Xu W, Krumm B, Jacobson KA.   +10 more
europepmc   +2 more sources

Enzymatic Glycosylation of <i>Ganoderma</i> Terpenoid via Bacterial Glycosyltransferases and Glycoside Hydrolases. [PDF]

Biomolecules
Glycosylation is a critical enzymatic modification that involves the attachment of sugar moieties to target compounds, considerably influencing their physicochemical and biological characteristics.
Chang TS, Wu JY, Ding HY, Wang TY.
europepmc   +2 more sources

Glucosylation of (±)-Menthol by Uridine-Diphosphate-Sugar Dependent Glucosyltransferases from Plants [PDF]

Molecules, 2021
Menthol is a cyclic monoterpene alcohol of the essential oils of plants of the genus Mentha, which is in demand by various industries due to its diverse sensorial and physiological properties. However, its poor water solubility and its toxic effect limit possible applications.
Elisabeth Kurze, Victoria Ruß, Nadia Syam, Isabelle Effenberger, Rafal Jonczyk, Jieren Liao, Chuankui Song, Thomas Hoffmann, Wilfried Schwab   +8 more
openaire   +4 more sources

Nucleoside Diphosphate-sugar 4-Epimerases I. Uridine Diphosphate Glucose 4-Epimerase of Wheat Germ [PDF]

Plant Physiology, 1969
Uridine diphosphate (UDP)-glucose 4-epimerase (EC 5.1.3.2) has been purified over 1000-fold from extracts of wheat germ by MnCl(2) treatment, (NH(4))(2)SO(4) fractionation, Sephadex column chromatography, and adsorption onto and elution from calcium phosphate gel. The enzyme has a pH optimum of 9.0.
D F, Fan, D S, Feingold
openaire   +5 more sources

GALE variants associated with syndromic manifestations, macrothrombocytopenia, bleeding, and platelet dysfunction

Platelets, 2023
GALE gene encodes the uridine diphosphate [UDP]-galactose-4-epimerase, which catalyzes the bidirectional interconversion of UDP-glucose to UDP-galactose, and UDP-N-acetyl-glucosamine to UDP-N-acetyl-galactosamine.
Ana Marín-Quílez, Christian A. Di Buduo, Rocío Benito, Alessandra Balduini, José Rivera, Jose Maria Bastida   +5 more
doaj   +1 more source

Identification of a carbohydrate recognition motif of purinergic receptors

eLife, 2023
As a major class of biomolecules, carbohydrates play indispensable roles in various biological processes. However, it remains largely unknown how carbohydrates directly modulate important drug targets, such as G-protein coupled receptors (GPCRs).
Lifen Zhao, Fangyu Wei, Xinheng He, Antao Dai, Dehua Yang, Hualiang Jiang, Liuqing Wen, Xi Cheng   +7 more
doaj   +1 more source

Highly efficient production of rebaudioside D enabled by structure-guided engineering of bacterial glycosyltransferase YojK

Frontiers in Bioengineering and Biotechnology, 2022
Owing to zero-calorie, high-intensity sweetness and good taste profile, the plant-derived sweetener rebaudioside D (Reb D) has attracted great interest to replace sugars.
Baodang Guo, Xiaodong Hou, Yan Zhang, Zhiwei Deng, Qian Ping, Kai Fu, Zhenbo Yuan, Yijian Rao   +7 more
doaj   +1 more source

UGT440A1 Is Associated With Motility, Reproduction, and Pathogenicity of the Plant-Parasitic Nematode Bursaphelenchus xylophilus

Frontiers in Plant Science, 2022
Pine wilt disease (PWD) caused by Bursaphelenchus xylophilus is considered a major threat to pine forests worldwide. Uridine diphosphate (UDP)-glycosyltransferases (UGTs) catalyze the conjugation of small lipophilic compounds with sugars and play crucial
Min Wang, Guicai Du, Junna Fang, Linsong Wang, Qunqun Guo, Tingting Zhang, Ronggui Li   +6 more
doaj   +1 more source

Hypothetical protein CuvA (Rv1422) from Mycobacterium tuberculosis H37Rv interacts with uridine diphosphate N-acetylglucosamine as a key precursor of cell wall

Applied Biological Chemistry, 2023
Mycobacterium tuberculosis CuvA (Rv1422, MtCuvA) has previously been suggested that it may play a critical role in nutrient utilization and cell wall synthesis required for physiological adaptation in a host cell, but its biochemical details remain ...
Yoon Chae Jeong, Jihyun Park, Yu Jeong Cheon, Ki Seog Lee   +3 more
doaj   +1 more source