Results 111 to 120 of about 23,635 (197)

Effect of Anthocyanin‐Rich New Zealand Blackcurrant on Tumour Necrosis Factor‐α–Induced Plasminogen Activator Inhibitor‐1 Release in Airway Epithelial Cells: A Preliminary Study

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Pretreatment with New Zealand blackcurrant anthocyanins nonsignificantly reduced TNF‐α–induced PAI‐1 release in bronchial epithelial cells. The small sample size may have influenced the lack of statistical significance. This study provides preliminary evidence of possible effects of NZBC anthocyanins on PAI‐1 secretion but warrants further extensive ...
Madiha Ajaz, Ayesha Zahid, Rati Jani, Lada Vugic, Indu Singh, Natalie Shilton   +5 more
wiley   +1 more source

The Aging Microenvironment Shapes Angiogenic Remodeling in IBD‐Associated Colorectal Carcinogenesis

Aging Cell, Volume 25, Issue 6, June 2026.
In IBD, chronic inflammation promotes cellular senescence across epithelial, stromal, endothelial, and immune compartments. The resulting SASP drives pathological angiogenesis, vascular dysfunction, hypoxia, and immune suppression, thereby facilitating progression from inflammation to dysplasia and colitis‐associated colorectal cancer.
Ruoshu Duan, Qingyu Chen, Yuan Xu, Ye Yan, Sujing Jiang   +4 more
wiley   +1 more source

Plasminogen Activator Inhibitor‐1 is Internalized by Endothelial Cells via A Pinocytosis‐Like Mechanism and Evades Degradation

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Plasminogen activator inhibitor 1 (PAI1) is a secreted protein that also regulates intracellular processes, such as inhibition of endothelial nitric oxide synthase (eNOS). Interaction between Plasminogen Activators (PA) and PAI1 results in a covalent linkage.
Molly McAdow, Gjina Ahmetaj, Rachel Hauschel, Anne Eichmann, William Sessa   +4 more
wiley   +1 more source

The autoactivation of human single-chain urokinase-type plasminogen activator (uPA). [PDF]

J Biol Chem, 2023
Torres-Paris C, Chen Y, Xiao L, Song HJ, Chen P, Komives EA.   +5 more
europepmc   +1 more source

Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer. [PDF]

Matrix Biol Plus, 2023
Micalet A, Tappouni LJ, Peszko K, Karagianni D, Lam A, Counsell JR, Quezada SA, Moeendarbary E, Cheema U.   +8 more
europepmc   +1 more source

Urokinase-Type Plasminogen Activator Receptor Regulates Prosurvival and Angiogenic Properties of Cardiac Mesenchymal Stromal Cells. [PDF]

Int J Mol Sci, 2023
Dergilev K, Tsokolaeva Z, Goltseva Y, Beloglazova I, Ratner E, Parfyonova Y.   +5 more
europepmc   +1 more source

Urokinase-Type Plasminogen Activator [PDF]

, 2020
openaire   +1 more source

Soluble urokinase-type plasminogen activator receptor in sickle cell disease-associated chronic kidney disease. [PDF]

Blood Adv, 2023
Afangbedji N, Kumari N, Diaz S, Wen F, Taylor JG, Nekhai S, Jerebtsova M.   +6 more
europepmc   +1 more source

The accuracy of soluble urokinase-type plasminogen activator receptor for the diagnosis of neonatal sepsis: a meta-analysis. [PDF]

Front Med (Lausanne), 2023
Ma J, Chen X, Wang X, Liang J, Guo L, Su Y, Hao L, Ren C.   +7 more
europepmc   +1 more source

Protective effect of Maixuekang on renal function in rats with unilateral ureteral obstruction and its underlying mechanism

Linchuang shenzangbing zazhi, 2016
Objective To observe the protective effect of Maixuekang on renal function in rats with unilateral ureteral obstruction(UUO),and to investigate the possible mechanism.Methods UUO model was established.Rats were divided into three groups:sham operation ...
LIANG Jing, ZHANG Yuan, CHEN Kai-feng, CAO Ling   +3 more
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