Results 121 to 130 of about 6,870,828 (229)
Tissue‐Resident Macrophage in Inflammation and Cancer
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang +13 more
wiley +1 more source
Related Article from Urokinase-Type Plasminogen Activator Receptor: A Beacon of Malignancy?
Related Article from Urokinase-Type Plasminogen Activator Receptor: A Beacon of ...
Ronny Drapkin (130800) +2 more
core +1 more source
This study screened hypoxia‐ischemia hub genes for AMI through transcriptomic bioinformatics and animal tests. Merging two GEO datasets yielded 633 DEGs; intersection with GeneCards hypoxia genes produced 21 HIRGs. PPI network and random forest identified core PLAUR and IL1B, whose diagnostic value was validated by GSE66360 via ROC, calibration, and ...
Longsheng Zhang, Ning Liang
wiley +1 more source
ABSTRACT Aim To analyse the clinical, technical, and demographic factors associated with tunnelled central venous catheter dysfunction in patients undergoing haemodialysis. Design Multicentre, retrospective session‐level observational study. Methods We analysed 40,193 haemodialysis sessions from 743 patients with tunnelled central venous catheters ...
Verónica Gimeno Hernán +7 more
wiley +1 more source
Role of Soluble Urokinase-Type Plasminogen Activator Receptor in Cardiovascular Disease. [PDF]
Ismail A, Hayek SS.
europepmc +1 more source
A microfluidic model of the glioblastoma (GBM) margin was developed to mimic patient‐specific blood‐brain tumor barrier (BBTB) function and drug response. The platform revealed inter‐patient variability in barrier integrity and drug sensitivity, offering a tool for personalized therapy evaluation in GBM.
Minsu Ryoo +16 more
wiley +1 more source
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama +16 more
wiley +1 more source
ABSTRACT Systemic chronic inflammation contributes to the development of many age‐related chronic diseases and represents a promising target for interventions aiming at promoting healthy aging. Fisetin is a naturally occurring flavonoid with anti‐inflammatory, antioxidant and senolytic effects in vitro and in animal models, but evidence from randomised
Juliette Tavenier +15 more
wiley +1 more source
Degradation and remodelling of the extracellular matrix is an essential feature in many pathophysiological processes, especially in invasive and angiogenesis-related diseases.
Hanemaaijer, R. +4 more
core +1 more source
OBJECTIVE: To determine distribution of urokinase plasminogen activator-like protein and urokinase plasminogen activator receptor-like protein in urinary tract tissues of healthy dogs. ANIMALS: 11 healthy dogs. PROCEDURES: Necropsy specimens from kidney,
Hosgood, Giselle +3 more
core +1 more source

