Results 121 to 130 of about 6,870,828 (229)

Tissue‐Resident Macrophage in Inflammation and Cancer

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang   +13 more
wiley   +1 more source

Related Article from Urokinase-Type Plasminogen Activator Receptor: A Beacon of Malignancy?

open access: yes, 2008
Related Article from Urokinase-Type Plasminogen Activator Receptor: A Beacon of ...
Ronny Drapkin (130800)   +2 more
core   +1 more source

Bioinformatics Analysis and Experimental Validation of Key Genes Associated With Hypoxia and Ischemia in Myocardial Infarction

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
This study screened hypoxia‐ischemia hub genes for AMI through transcriptomic bioinformatics and animal tests. Merging two GEO datasets yielded 633 DEGs; intersection with GeneCards hypoxia genes produced 21 HIRGs. PPI network and random forest identified core PLAUR and IL1B, whose diagnostic value was validated by GSE66360 via ROC, calibration, and ...
Longsheng Zhang, Ning Liang
wiley   +1 more source

Clinical and Technical Factors Associated With Tunnelled Central Venous Catheter Dysfunction in Haemodialysis: A Multicentre Session‐Level Retrospective Study

open access: yesNursing Open, Volume 13, Issue 9, September 2026.
ABSTRACT Aim To analyse the clinical, technical, and demographic factors associated with tunnelled central venous catheter dysfunction in patients undergoing haemodialysis. Design Multicentre, retrospective session‐level observational study. Methods We analysed 40,193 haemodialysis sessions from 743 patients with tunnelled central venous catheters ...
Verónica Gimeno Hernán   +7 more
wiley   +1 more source

Human Blood‐Brain Tumor Barrier on a Chip to Investigate Personalized Treatment for Glioblastoma Patients

open access: yesSmall, Volume 22, Issue 49, 1 September 2026.
A microfluidic model of the glioblastoma (GBM) margin was developed to mimic patient‐specific blood‐brain tumor barrier (BBTB) function and drug response. The platform revealed inter‐patient variability in barrier integrity and drug sensitivity, offering a tool for personalized therapy evaluation in GBM.
Minsu Ryoo   +16 more
wiley   +1 more source

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

open access: yesAllergy, Volume 81, Issue 9, Page 3171-3184, September 2026.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama   +16 more
wiley   +1 more source

Low‐Dose Fisetin Supplementation and Its Association With Chronic Inflammation in Middle‐Aged and Older Adults: Study Protocol for a Triple‐Blind, Randomised, Placebo‐Controlled Trial

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.
ABSTRACT Systemic chronic inflammation contributes to the development of many age‐related chronic diseases and represents a promising target for interventions aiming at promoting healthy aging. Fisetin is a naturally occurring flavonoid with anti‐inflammatory, antioxidant and senolytic effects in vitro and in animal models, but evidence from randomised
Juliette Tavenier   +15 more
wiley   +1 more source

Inhibition of urokinase-type and tissue-type plasminogen activator - Mediated plasminogen activation by doxycycline

open access: yes, 1996
Degradation and remodelling of the extracellular matrix is an essential feature in many pathophysiological processes, especially in invasive and angiogenesis-related diseases.
Hanemaaijer, R.   +4 more
core   +1 more source

Immunohistochemical staining of urokinase plasminogen activator-like and urokinase plasminogen activator receptor-like proteins in the urinary tract of healthy dogs

open access: yes, 2006
OBJECTIVE: To determine distribution of urokinase plasminogen activator-like protein and urokinase plasminogen activator receptor-like protein in urinary tract tissues of healthy dogs. ANIMALS: 11 healthy dogs. PROCEDURES: Necropsy specimens from kidney,
Hosgood, Giselle   +3 more
core   +1 more source

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