Results 101 to 110 of about 175,762 (228)

Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines

Journal of Neuroinflammation, 2019
Background Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants.
Paola Pontecorvi, Michael A. Banki, Carlotta Zampieri, Cristina Zalfa, Pardis Azmoon, Maria Z. Kounnas, Cinzia Marchese, Steven L. Gonias, Elisabetta Mantuano   +8 more
doaj   +1 more source

Lipoprotein(a), Endothelial Dysfunction and Cardiovascular Disease

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Lipoprotein(a) (Lp(a)) is a particle similar to low‐density lipoprotein cholesterol and is associated with apolipoprotein (A). High Lp(a) levels are a genetic, independent risk factor for atherosclerotic cardiovascular disease (ASCVD). Endothelial cells, which form the continuous lining of the cardiovascular system, are crucial for vascular ...
Xianghui Zhou, Xiyuan Fang, Xin Zhou, Zhao Zhang, Yu Hu, Zhipeng Cheng   +5 more
wiley   +1 more source

Urokinase-type plasminogen activator receptor

, 2003
A polypeptide presenting an epitope cross-reactive with an epitope of urokinase-type plasminogen activator receptor, and/or having uPA binding activity, is described.
Pollanen,, Jari, Vaheri,, Antti, Dano, Keld, Pyke, Charles, Masucci, Maria, Teresa, Roldan, Ann, Louring, Behrendt, Niels, Ploug, Michael, Cubellis, Maria, Vittoria, Ronne, Ebbe, Tapiovaara,, Hannele, Lund Leif, Roge, Patthy, Laszlo, Salonen,, Eeva-Marjatta, Moller Lisbeth, Birk, Ellis, Vincent, Stephens, Ross, W, Blasi, Francesco, Appella,, Ettore, Schleuning,, Wolf-Dieter, Kristensen, Peter   +20 more
core  

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Surface α-enolase promotes extracellular matrix degradation and tumor metastasis and represents a new therapeutic target.

PLoS ONE, 2013
In previous research, we found α-enolase to be inversely correlated with progression-free and overall survival in lung cancer patients and detected α-enolase on the surface of lung cancer cells.
Kuan-Chung Hsiao, Neng-Yao Shih, Hsun-Lang Fang, Tze-Sing Huang, Ching-Chuan Kuo, Pei-Yi Chu, Yi-Mei Hung, Shao-Wen Chou, Yi-Yuan Yang, Gee-Chen Chang, Ko-Jiunn Liu   +10 more
doaj   +1 more source

Soluble urokinase plasminogen activator receptor (suPAR) (ng/ml) in blood donors according to sex and age.

, 2014
Soluble urokinase plasminogen activator receptor (suPAR) (ng/ml) in blood donors according to sex and age.
Christian Thorball (569556), Eva Haastrup (423039), Lars Vedel Kessing (176727), Jesper Eugen-Olsen (39433), Henrik Ullum (308103), Katrine Grau (349910)   +5 more
core   +1 more source

Plasma Soluble Urokinase Plasminogen Activator Receptor in Children with Urinary Tract Infection

, 2011
Objective In this prospective study we investigated the role of plasma levels of soluble urokinase plasminogen activator receptor (suPAR) in children with urinary tract infection.
Lone Lindholm, Per Wittenhagen, Jesper Brandt Andersen, Jørn Theil, Anita Hansen, Jesper Eugen-Olsen, Frederik Rønne, Michael Tvede   +7 more
core   +1 more source

Pathogenic and Regulatory Roles of Fibrinolytic Factors in Autoimmune Diseases

Current Issues in Molecular Biology
Autoimmune diseases arise from complex interactions of genetic, environmental, and hormonal factors, yet their precise causes remain elusive. Beyond its canonical role in fibrin degradation, the fibrinolytic system is increasingly recognized as both a ...
Yosuke Kanno
doaj   +1 more source

Serum profiling of uPA, PAI-1, and suPAR in systemic sclerosis: a preliminary study on analytical aspects and associations with microvascular and fibrotic manifestations

Frontiers in Immunology
IntroductionIn systemic sclerosis (SSc), the laboratory panel lacks biomarkers able to predict the disease course and/or reflect the fibrotic activity in the skin and internal organs.
Filomena Napolitano, Ilaria Mormile, Ilaria Mormile, Gabriele Mignogna, Amato de Paulis, Amato de Paulis, Francesca Wanda Rossi, Francesca Wanda Rossi, Nunzia Montuori, Nunzia Montuori   +9 more
doaj   +1 more source

Video from Structure-based design of an urokinase-type plasminogen activator receptor–derived peptide inhibiting cell migration and lung metastasis

, 2009
Video from Structure-based design of an urokinase-type plasminogen activator receptor–derived peptide inhibiting cell migration and lung ...
Mario De Rosa (15040481), Liliana Lista (2709868), Giuseppina Votta (2141533), Maria Vincenza Carriero (8713431), Renato Franco (184143), Maria Teresa Masucci (15040478), Maria Patrizia Stoppelli (133653), Katia Bifulco (133627), Vincenzo Pavone (133641), Claudio Arra (133331), Antonio Barbieri (458558), Immacolata Longanesi-Cattani (133632), Ornella Maglio (4379920)   +12 more
core   +1 more source