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Modulation of lipoxidase activity by urokinase-type plasminogen activator

Prostaglandins, Leukotrienes and Essential Fatty Acids, 1994
Malignant cells show increased urokinase (UK) activity and decreased peroxidation of essential fatty acids (EFA). In order to explore this phenomenon the effect of UK on the lipoxidase activity was spectrophotometrically investigated. Decreased lipoxidase activity was obtained with increased UK concentrations (r = -1.000, p < 0.0001).
C H, van Aswegen   +2 more
openaire   +2 more sources

The murine urokinase-type plasminogen activator gene

Biochemistry, 1987
The murine urokinase-type plasminogen activator (uPA) gene has been isolated from a BALB/c liver DNA cosmid library and its nucleotide sequence established. The gene is organized into 11 exons comprising 34.7% of the 6710 base pair (bp) region spanning the interval between the presumed transcription initiation and polyadenylation sites.
S J, Degen   +3 more
openaire   +2 more sources

No crossreaction between circulating plasminogen activator and urokinase

Thrombosis Research, 1979
Abstract Malignant ovarian tumours release a urokinase-like plasminogen activator which could be a biological marker for the tumour and detected in a radioimmunoassay. The immunoreactivity of the physiological, circulating blood plasminogen activator released from the vessel wall was therefore studied in six healthy volunteers after venous occlusion.
openaire   +2 more sources

Inhibition of the Plasminogen Activator Urokinase by Alpha-Tocopherol

Acta Haematologica, 2009
α-Tocopherol (vitamin E) inhibited the activity of urokinase on fibrin plates and on the amidolytic substrate S-2444 in a concentration- and time-dependent manner. Inhibition was not removed by dialysis. In the presence of dilutions of plasma, protein-containing fractions of gel-filtered plasma, or bovine serum albumin, the inhibition of urokinase by α-
openaire   +2 more sources

Plasminogen Activation by Receptor-Bound Urokinase

Seminars in Thrombosis and Hemostasis, 1991
V, Ellis, K, Danø
openaire   +2 more sources

Urokinase-Type Plasminogen Activator Antigen and Early Relapse in Breast Cancer.

Lancet, The, 1989
F Jänicke, Fritz Janicke, Henner Graeff
exaly  

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