Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis [PDF]
Ying-Na Bao +22 more
openalex +1 more source
Dattabase Information from Structure-based design of an urokinase-type plasminogen activator receptor–derived peptide inhibiting cell migration and lung metastasis [PDF]
Maria Vincenza Carriero +12 more
openalex +1 more source
ABSTRACT Dysregulation of the nuclear factor kappa B (NF‐κB) signaling pathway is closely associated with inflammation‐driven carcinogenesis, tumor progression and resistance to conventional therapies. Sustained NF‐κB activation enhances malignant cell survival, proliferation and immune evasion by promoting proinflammatory and antiapoptotic gene ...
Maria Sharif +10 more
wiley +1 more source
Soluble Urokinase Receptor and Mortality in Kidney Transplant Recipients. [PDF]
Morath C +7 more
europepmc +1 more source
SP235SOLUBLE UROKINASE TYPE PLASMINOGEN ACTIVATOR RECEPTOR AS A PREDICTOR OF CHRONIC KIDNEY DISEASE [PDF]
Ana Carina Ferreira +3 more
openalex +1 more source
Social Support as a Determinant of Dietary Quality in Community‐Dwelling Older Adults in China
Diet quality and social support play essential roles in maintaining the health of older adults. However, the relationship between these factors remains uncertain. This study aimed to investigate the association between social support and dietary quality among community‐dwelling older adults in China.
Xiaoyan Zhang +5 more
wiley +1 more source
The Role of Macrophages in Cancer: From Basic Research to Clinical Applications
Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu +5 more
wiley +1 more source
Supplementary Data from Targeting the Urokinase Plasminogen Activator Receptor Inhibits Ovarian Cancer Metastasis [PDF]
Hilary A. Kenny +9 more
openalex +1 more source
eVLP‐Mediated Cas9 Delivery for Preventing IBMIR in Islet Transplantation
Engineered virus‐like particles (eVLPs) are used to deliver Cas9 nuclease to knock out tissue factor (TF) and plasminogen activator inhibitor‐1 (PAI‐1) genes in pancreatic islets. The edited islets maintained viability and function, while reducing instant blood‐mediated inflammatory reaction (IBMIR) markers and improving glycemic control in diabetic ...
Manju Shrestha +6 more
wiley +1 more source

