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RETRACTED: Kshirsagar et al. A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer’s Disease. Cells 2022, 11, 2660 [PDF]

open access: yesCells
The journal retracts the article titled “A Combination Therapy of Urolithin A+EGCG Has Stronger Protective Effects than Single Drug Urolithin A in a Humanized Amyloid Beta Knockin Mice for Late-Onset Alzheimer’s Disease” [...]
Sudhir Kshirsagar   +8 more
doaj   +3 more sources

A Novel Streptococcus thermophilus FUA329 Isolated from Human Breast Milk Capable of Producing Urolithin A from Ellagic Acid

open access: yesFoods, 2022
Urolithin A, a metabolite of ellagic acid, has many beneficial biological activities for people. Strains capable of producing urolithin A from ellagic acid have the hope of becoming the next-generation probiotics.
Qitong Liu   +8 more
doaj   +2 more sources

Fucus vesiculosus Polysaccharide-Based Solid Dispersions Enhance Aqueous Dispersion and Gut Microbial Biotransformation of Ellagic Acid [PDF]

open access: yesFoods
Ellagic acid (EA) is a food-derived polyphenol with multiple biological activities, but its poor water solubility and aggregation in aqueous systems limit its accessibility to gut microorganisms.
Rui-Bo Jia   +6 more
doaj   +2 more sources

Urolithin A has antiplatelet effects in contrast to its glucuronide, urolithin B, and isourolithin A [PDF]

open access: yesFrontiers in Cardiovascular Medicine
IntroductionConsumption of dietary ellagitannins has been suggested to have protective effects against cardiovascular disease, likely due to the colonic formation of urolithins and their subsequent systemic absorption.
Alina Soloviova   +6 more
doaj   +2 more sources

Isolation of Human Intestinal Bacteria Capable of Producing the Bioactive Metabolite Isourolithin A from Ellagic Acid [PDF]

open access: yesFrontiers in Microbiology, 2017
Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma   +7 more
doaj   +2 more sources

Urolithin-A attenuates neurotoxoplasmosis and alters innate response towards predator odor

open access: yesBrain, Behavior, & Immunity - Health, 2020
Neurotoxoplasmosis, also known as cerebral toxoplasmosis, is an opportunistic chronic infection caused by the persistence of parasite Toxoplasma gondii cysts in the brain.
Sijie Tan, Wen Han Tong, Ajai Vyas
doaj   +2 more sources

Urolithin M5 from the Leaves of Canarium album (Lour.) DC. Inhibits Influenza Virus by Targeting Neuraminidase

open access: yesMolecules, 2022
Ganlanye (GLY), the leaf of Canarium album (Lour.) DC., is a traditional Chinese medicinal herb for warm disease treatment. We found that its aqueous extract could inhibit the influenza A virus.
Mengjie Xiao   +5 more
doaj   +2 more sources

Metagenomic insights into urolithin formation from rambutan rind extract by rat faecal-derived microbiome [PDF]

open access: yesApplied Microbiology and Biotechnology
Ellagitannins and ellagic acid are microbially converted into urolithins, metabolites associated with antioxidant, anti-inflammatory, and mitochondrial-related activities.
Wai-Kit Tow   +6 more
doaj   +2 more sources

Urolithin A Protects Ovarian Reserve Via Inhibiting PI3K/Akt Signaling and Preventing Chemotherapy-Induced Follicle Apoptosis

open access: yesBiology
Urolithin A, which is a natural gut microbial metabolite, exerts multiple beneficial effects upon supplementation, including prolonging lifespan, mitigating diseases, restoring the quality of aged oocytes and alleviating drug toxicity.
Weiyong Wang   +3 more
doaj   +2 more sources

Preclinical Evaluation of Oral Urolithin-A for the Treatment of Acute Campylobacteriosis in Campylobacter jejuni Infected Microbiota-Depleted IL-10−/− Mice

open access: yesPathogens, 2020
Human campylobacteriosis represents an infectious enteritis syndrome caused by Campylobacter species, mostly Campylobacter jejuni. Given that C. jejuni infections are rising worldwide and antibiotic treatment is usually not indicated, novel treatment ...
Soraya Mousavi   +3 more
doaj   +2 more sources

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