Interactions between Gut Microbiota and Polyphenols: New Insights into the Treatment of Fatigue
Molecules, 2022 Fatigue seriously affects people’s work efficiency and quality of life and has become a common health problem in modern societies around the world. The pathophysiology of fatigue is complex and not fully clear.
Chuanhong Luo +8 more
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Biochemistry and Biophysics Reports, 2020 Mediated by the nuclear vitamin D receptor (VDR), the hormonally active vitamin D metabolite, 1,25-dihydroxyvitamin D3 (1,25D), is known to regulate expression of genes impacting calcium and phosphorus metabolism, the immune system, and behavior ...
Sarah Livingston +9 more
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Urolithins: The Colon Microbiota Metabolites as Endocrine Modulators: Prospects and Perspectives
Frontiers in Nutrition, 2022 Selective estrogen receptor modulators (SERMs) have been used in hormone related disorders, and their role in clinical medicine is evolving. Tamoxifen and raloxifen are the most commonly used synthetic SERMs, and their long-term use are known to create ...
Ravindran Vini +8 more
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Molecules, 2016 The consumption of foodstuffs yielding circulating compounds able to maintain endothelial function by improving nitric oxide (NO) bioavailability can be considered as an effective strategy for cardiovascular disease prevention.
Valentina Spigoni +7 more
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The Compound Specific Antibacterial Activities of Major Urolithins and Their Methyl Ethers
Journal of the Turkish Chemical Society, Section A: Chemistry, 2021 The investigation of biological activities of natural products, particularly considering the secondary metabolites, continuously receives attention.
Hayrettin Ozan GÜLCAN +4 more
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Life, 2022 In our continued study on the anti-HIV activity of compounds present in CareVidTM, we report the HIV-1 integrase ((HIV-1 IN) inhibitory effects of pellitorine (1), oleuropein (2), magnoflorine (3), crotepoxide (4), ent-kaurane-16β,17-diol (5 ...
Winnie Rotich +5 more
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The gut microbiota metabolism of pomegranate or walnut ellagitannins yields two urolithin-metabotypes that correlate with cardiometabolic risk biomarkers: Comparison between normoweight, overweight-obesity and metabolic syndrome. [PDF]
, 2018 Background & aims: Urolithins are microbial metabolites produced after consumption of ellagitannincontaining foods such as pomegranates and walnuts.
Espín, Juan Carlos +20 more
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Urolithin B: Two-way attack on IAPP proteotoxicity with implications for diabetes
Frontiers in Endocrinology, 2022 IntroductionDiabetes is one of the major metabolic diseases worldwide. Despite being a complex systemic pathology, the aggregation and deposition of Islet Amyloid Polypeptide (IAPP), or amylin, is a recognized histopathological marker of the disease ...
Ana F. Raimundo +15 more
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Colonization in Newly Born: The Role of Mothers’ Urolithin Metabotypes
, 2020 The maternal-infant transmission of several urolithins through breast milk and the gut colonization of infants by the urolithin-producing bacterium Gordonibacter during their first year of life were explored.
Ana Rodríguez-Varela +17 more
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Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults A Randomized Clinical Trial [PDF]
, 2022 IMPORTANCE Aging is associated with a decline in mitochondrial function and reduced exercise capacity. Urolithin A is a natural gut microbiome-derived food metabolite that has been shown to stimulate mitophagy and improve muscle function in older animals
Garcia, Jose M. +17 more
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