Early mitophagy activation by Urolithin A prevents, but late activation does not reverse, age-related cognitive impairment. [PDF]
Jara C +6 more
europepmc +1 more source
Mitochondrial Dysfunction in Alzheimer's Disease and Mitochondria-Targeted Therapeutics. [PDF]
Bisht J, Rawat P, Shin AC, Hegde V.
europepmc +1 more source
Eicosapentaenoic Acid and Urolithin a Synergistically Mitigate Heat Stroke-Induced NLRP3 Inflammasome Activation in Microglial Cells. [PDF]
Cho H, Kim J, Park Y, Kim YC, Chung S.
europepmc +1 more source
Urinary polyphenol signature of the Mediterranean diet is associated with lower cardiovascular disease risk: the PREDIMED trial. [PDF]
Domínguez-López I +23 more
europepmc +1 more source
Polyphenols Bioactive Metabolites, and Their Anti-Biofilm and Neuroprotective Potential. [PDF]
Nazzaro F +7 more
europepmc +1 more source
Immunomodulatory Role of Urolithin A on Metabolic Diseases [PDF]
Urolithin A (UroA) is a gut metabolite produced from ellagic acid-containing foods such as pomegranates, berries, and walnuts. UroA is of growing interest due to its therapeutic potential for various metabolic diseases based on immunomodulatory properties.
Soonkyu Chung +2 more
exaly +5 more sources
Urolithin and Reduced Urolithin Derivatives as Potent Inhibitors of Tyrosinase and Melanogenesis: Importance of the 4-Substituted Resorcinol Moiety [PDF]
We previously reported (E)-β-phenyl-α,β-unsaturated carbonyl scaffold ((E)-PUSC) played an important role in showing high tyrosinase inhibitory activity and that derivatives with a 4-substituted resorcinol moiety as the β-phenyl group of the scaffold resulted in the greatest tyrosinase inhibitory activity.
Hee Jin Jung, , Pusoon Chun
exaly +3 more sources

