Results 111 to 120 of about 3,771 (207)

Anti-inflammatory and Antioxidant Mechanism of Urolithin B in Activated Microglia

, 2018
Urolithin B is one of the gut microbial metabolites of ellagitannins, which have a number of biological activities such as anti-cancer, anti-microbial, anti-inflammatory, antioxidant, and neuroprotective effects. Urolithin B showed anti-cancer activities
이경진
core  

Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway

Nature Communications, 2019
Urolithins are microbial metabolites derived from food polyphenols. Here, Singh et al. show that urolithin A and a synthetic analogue enhance gut barrier function via Nrf2-dependent pathways and mitigate inflammation and colitis in mice, highlighting a ...
Rajbir Singh, Sandeep Chandrashekharappa, Sobha R. Bodduluri, Becca V. Baby, Bindu Hegde, Niranjan G. Kotla, Ankita A. Hiwale, Taslimarif Saiyed, Paresh Patel, Matam Vijay-Kumar, Morgan G. I. Langille, Gavin M. Douglas, Xi Cheng, Eric C. Rouchka, Sabine J. Waigel, Gerald W. Dryden, Houda Alatassi, Huang-Ge Zhang, Bodduluri Haribabu, Praveen K. Vemula, Venkatakrishna R. Jala   +20 more
doaj   +1 more source

Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults A Randomized Clinical Trial

IMPORTANCE Aging is associated with a decline in mitochondrial function and reduced exercise capacity. Urolithin A is a natural gut microbiome-derived food metabolite that has been shown to stimulate mitophagy and improve muscle function in older animals
Garcia, Jose M., Liu, Sophia, Aebischer, Patrick, Rinsch, Chris, D'Amico, Davide, Bhayana, Saakshi, Singh, Anurag, Shankland, Eric, Marcinek, David J.   +8 more
core   +1 more source

Investigating the Cytotoxic Effect of Urolithin B and Cerium Oxide Nanoparticles Synthesized from Aloe Vera Plant on Brain Cancer Cell Colony (U87MG)

, 2023
Background: Brain cancer is one of the types of cancer that appears with the growth of cancer cells in the brain. In this experimental study, we investigated and compared the effect of cerium oxide nanoparticles synthesized by the green method from Aloe ...
Ghasem Rahimi kalateh shah mohammad, Rahele Zhiani, Majid Darrudi, Alireza Motavalizadeh kakhky, Jamshid Mehrzad   +4 more
core  

Computational Study of Some Urolithin Derivatives-based Biomass Corrosion Inhibitors on the Fe (110), Cu(111) and Al(111) Surface

ARO-The Scientific Journal of Koya University
Corrosion poses a significant economic and environmental burden, highlighting the need for sustainable corrosion inhibitors. This study investigates the potential of urolithin derivatives (UroE, UroM5, UroM6, and UroM7) as eco-friendly corrosion ...
Rebaz A. Omer
doaj   +1 more source

Synthesis of urolithin A 3- and 8-glucuronides via intramolecular biaryl coupling

Results in Chemistry
Urolithins, 6H-dibenzo[b,d]pyran-6-one derivatives, are metabolites produced by gut microbiota from ellagic acid, a natural antioxidant. They are more efficiently absorbed than ellagic acid and contribute to the health benefits of ellagitannin-rich foods.
Takanori Nagai, Shaikh Shoeb, Tsuyoshi Nishimori, Hiroyuki Tachi, Anees Pangal, Hitoshi Abe   +5 more
doaj   +1 more source

Urolithin metabotypes can anticipate the different restoration of the gut microbiota and anthropometric profiles during the first year postpartum

, 2019
© 2019 by the authors.The metabolism of dietary polyphenols ellagitannins by the gut-microbiota allows the human stratification in urolithin metabotypes depending on the final urolithins produced.
Ana Rodríguez-Varela, Izaskun García-Mantrana, García Mantrana, Izaskun, María Romo-Vaquero, Romo Vaquero, María, Adrián Cortés-Martín, Rodríguez-Varela, Ana, Selma, María Victoria, María Victoria Selma, María Carmen Collado, Cortés-Martín, Adrián, Juan Carlos Espín, Espín de Gea, Juan Carlos, Collado, María Carmen   +13 more
core   +1 more source

Fermentative Liberation and Transformation of Bioactive Compounds: Ellagic Acid from Nut Press Cake Ellagitannins

Applied Sciences
Oil extracted from walnuts leaves behind large amounts of defatted press cake that still retains valuable nutrients. Solid state fermentation (SSF) is a promising method to liberate bioactive compounds from food by-products.
Wolfram Manuel Brück, Yannick Erismann, Wilfried Andlauer   +2 more
doaj   +1 more source

Unlocking the Therapeutic Potential of Ellagic Acid for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis

Antioxidants
Obesity is in epidemic proportions in many parts of the world, contributing to increasing rates of non-alcoholic fatty liver disease (NAFLD). NAFLD represents a range of conditions from the initial stage of fatty liver to non-alcoholic steatohepatitis ...
Tharani Senavirathna, Armaghan Shafaei, Ricky Lareu, Lois Balmer   +3 more
doaj   +1 more source

Properties of Water Extracts of Rambutan Peel Polyphenols during in Vitro Simulated Gastrointestinal Digestion and Colonic Fermentation and Their Effects on Gut Microbiota

Shipin gongye ke-ji
The rambutan peel was rich in polyphenols, in order to further investigate the technology of rambutan peel polyphenol production and its product development, this study prepared rambutan peel polyphenol water extract (RPE) by high pressure steaming ...
Jiao LI, Qiuming LIU, Liyuan BA, Yinsuo LUO, Yongliang ZHUANG, Xing WAN, Liping SUN   +6 more
doaj   +1 more source