Results 91 to 100 of about 4,989 (225)
Treating age‐related loss of muscle mass and function: Where should we be focusing?
The Journal of Physiology, EarlyView.Abstract figure legend Perturbations contributing to the age‐related loss of muscle mass and strength. A, in the spinal cord, self‐reinforcing cycles of oxidative stress, mitochondrial dysfunction and inflammation mediated by cells, including microglia, contribute to motor neuron degeneration.Daniel J. Ham, Christopher S. Fry, Avnika Ashok Ruparelia, Shyuan T. Ngo, Séverine Lamon +4 morewiley +1 more sourceDietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities
Food Science &Nutrition, Volume 14, Issue 5, May 2026.This illustration highlights how dietary polyphenols from foods like berries, grapes, and green tea travel through the gut, where microbiota transform them into bioactive metabolites. These metabolites pass into the bloodstream, strengthen the gut barrier, and ultimately reach the brain, supporting neuroprotection through antioxidative and anti ...Adnan Akif, Jannatul Wahid Munami, Rajib Das, Nusrat Jahan Shawon +3 morewiley +1 more sourceGut microbiota functions: metabolism of nutrients and other food components [PDF]
, 2017 The diverse microbial community that inhabits the human gut has an extensive metabolic repertoire that is distinct from, but complements the activity of mammalian enzymes in the liver and gut mucosa and includes functions essential for host digestion. As A Alonso, A Belenguer, A Bordbar, A Braune, A Braune, A Duda-Chodak, A El Kaoutari, A Heinken, A Heinken, A Heinken, A Heinken, A Heinken, A Karau, A Marcobal, A Matthies, A Matthies, A Mohammed, A Quartieri, A-HM Emwas, A-M Davila, AF Hofmann, AJ Brown, AK Mallett, Almut Heinken, AR Rechner, AR Zomorrodi, AW Walker, AW Walker, B Goodwin, BE Gustafsson, BE Gustafsson, BV Jones, C Manach, C Noecker, CA Kolmeder, CA Kolmeder, CB Cole, CIR Gill, CJ Ziemer, CS Song, D Couteau, DH Mallonee, E Bauer, EA Franzosa, EA Smith, EM Lenz, EP Halmos, F Abram, F Bastos, F Suarez, F Tomas-Barberan, F Vadder De, FA Tomas-Barberan, FA Tomas-Barberan, FE Rowan, FM McIntosh, G Corona, G Falony, G Frost, G Wu, Glenn Gibson, GR Gibson, GR Gibson, GT Macfarlane, GT Macfarlane, GW Tannock, H Bernstein, H Hirokane, H Kettle, H Kettle, H Roume, H Tazoe, HM Said, I Rowland, Ian Rowland, IEJA Francois, Ines Thiele, J Eldere Van, J Pérez-Jiménez, J Trygg, JA Flick, JC Garcia-Canaveras, JC Young, JG Le Blanc, JH Cummings, JJ Eloranta, JK Nicholson, JM Landete, JM Ridlon, JM Ridlon, Jonathan Swann, JR Marchesi, JR Swann, JT Bjerrum, JW Lampe, K Decroos, K Steliou, K Watanabe, Karen Scott, Kieran Tuohy, KP Scott, KR Stayrook, L Hanske, L Hanske, L Marín, L Tasse, L Tomasova, LA Woollett, LV Hooper, M Begley, M Blaut, M Dabek, M Hermanussen, M Rajilić-Stojanović, M Vital, M Watanabe, M Watanabe, MB Biggs, MD Levitt, MGM Kok, MJ Gosalbes, MJ Hill, MV Selma, N Reichardt, NC Verberkmoes, NE Lewis, O Manor, P Kurdi, P Louis, P Louis, P Louis, P Louis, Palsson BØ, PC Pircher, PG Frick, PG Wolf, PJ Turnbaugh, Q Zhang, R Madsen, R Muñoz-Tamayo, RL Kandell, S El Aidy, S Greenblum, S Katsuma, S Lockyer, S Magnúsdóttir, S Possemiers, SA Gibson, SA Joyce, SD Boyd, SF Lajoie, SH Duncan, SH Duncan, SH Hussaini, SM Houten, SN Steinway, SU Christl, SU Christl, T Clavel, T Clavel, T Shashkova, W Xiong, W-L Wang, WR Russell, WR Russell, WR Wikoff, X Shen, X Wei, Y Wang, Z Wang, Z-L Dai, Z-L Dai +171 morecore +3 more sourcesGap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT
To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...Robin I. Kuijpers, Isabel O. de Moya Clark, Tomás Cavaco, Vivian Nemanič, Beatrice Tagliabue, Ainhoa Valero‐Abad, Wiebe M. Wennekers, Mengqiu Zhang, Koen Van Zwet, Sanne Abeln, Sofia Moco, Caroline E. Paul, Halima Mouhib, Richard A. Notebaart, Eddy J. Smid, Bas Teusink, Herwig Bachmann +16 morewiley +1 more sourceInteractions of Different Urolithins With Bovine Serum Albumin
Natural Product Communications, 2023 Backgound/Objectives Urolithins (UROs) are the metabolites derived from the gut microbial action on ellagitannins and ellagic acid-rich foods. Following their absorption in the intestine, UROs are transported through the systemic circulation to various ...Nevena Zelenovic, Milica Kojadinovic, Lidija Filipovic, Vesna Vucic, Milos Milcic, Aleksndra Arsic, Milica Popovic +6 moredoaj +1 more sourceThe role of polyphenols in modern nutrition [PDF]
, 2017 Polyphenols are found in plant-based foods and beverages, notably apples, berries, citrus fruit, plums, broccoli, cocoa, tea and coffee, and many others. There is substantial epidemiological evidence that a diet high in polyphenol-rich fruit, vegetables, Actis-Goretta, Actis-Goretta, Arab, Bakuradze, Bhupathiraju, Borges, Brull, Brull, Buitrago-Lopez, Buscemi, Buscemi, Cermak, Cifuentes-Gomez, Conquer, Cooper, Crippa, Ding, Ding, Dower, Dower, Drezner, EFSA NDA Panel (European Food Safety Authority Panel on Dietetic Products, Nutrition and Allergies), Egert, Egert, Ellam, Esposito, Fumeaux, Garcia-Alvarez, Guo, Guo, Hara, Heiss, Hertog, Hollman, Hooper, Hubbard, Jaganath, Jimenez, Jumar, Kay, Kempf, Kerimi, Kim, Lee, Leveques, Loke, Martin, Martini, Mastroiacovo, McAnulty, Mullen, Neilson, Neveu, Nieman, Nishimuro, Olthof, Olthof, Ottaviani, Ottaviani, Pan, Pang, Peluso, Perez-Jimenez, Petri, Pimpao, Pinto, Rhee, Rio, Romo-Vaquero, Santesso, Santos, Scalbert, Schmit, Serafini, Shaposhnikov, Shi, Shi, Stoupi, Urgert, Urgert, Vargas-Murga, Vlachojannis, Vogiatzoglou, Vogiatzoglou, Watanabe, Williamson, Williamson, Williamson, Woodward, Yahya, Yang, Yang, Yang, Zock +93 morecore +1 more sourceGut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis
Advanced Science, Volume 13, Issue 20, 9 April 2026.This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang +9 morewiley +1 more sourceBenefits of polyphenols on gut microbiota and implications in human health [PDF]
, 2017 The biological properties of dietary polyphenols are greatly dependent on their bioavailability that, in turn, is largely influenced by their degree of polymerization.Andrés Lacueva, Ma. Cristina, Cardona, Fernando, Queipo Ortuño, María Isabel, Tinahones, Francisco J., Tulipani, Sara +4 morecore +1 more sourceGALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer
Advanced Science, Volume 13, Issue 19, 2 April 2026.The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang +9 morewiley +1 more source