Results 81 to 90 of about 4,311 (206)
Food Biomacromolecules, Volume 3, Issue 3, Page 444-465, September 2026.Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley +1 more source
, 2022 Urolithin A is an active compound of gut-microbiota-derived metabolites of polyphenol ellagic acid that has anti-aging, antioxidative, and anti-inflammatory effects.
Chao, Jane C-J +13 more
core +1 more source
MedComm, Volume 7, Issue 9, September 2026.Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan +9 more
wiley +1 more source
Urolithin A Alleviates Doxorubicin-Induced Senescence in Mesenchymal Stem Cells
The accumulation of senescent cells, characterized by a pro-inflammatory secretory phenotype (SASP), metabolic dysfunction, and irreversible cell cycle arrest, is a driving force behind numerous age-related pathologies and directly undermines the ...
Kalinin, Alexander +7 more
core +1 more source
Enzyme and Microbial TechnologyUrolithins are metabolites derived from ellagic acid, a compound that is present in many plants, including pomegranate, via the action of gut microorganisms. Among them, urolithin A exhibits antioxidant and anti-inflammatory activity and promotes autophagy, making it a potential contributor to human health.
Anno, Katasho +7 more
openaire +2 more sources
Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 9, September 2026.Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li +3 more
wiley +1 more source
Metabolic Syndrome: From Mechanisms to Therapeutic Interventions
MedComm, Volume 7, Issue 9, September 2026.A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley +1 more source
Aging Cell, Volume 25, Issue 9, September 2026.The aging of the human body is a complex process driven by multiple contributing factors. Based on their underlying mechanisms, current anti‐aging interventions can be classified into six primary categories. This paper summarizes the most promising anti‐aging strategies within each class. ABSTRACT The global prevalence of aging and age‐related diseases
Feifei Li +4 more
wiley +1 more source
Urolithin A prevents age-related hearing loss by mitophagy induction in C57BL/6J mice
Figure 1. Effect of Urolithin A (UA) on hearing and the mitochondrial state.Figure 2. Effect of Urolithin A (UA) on expression levels of mitophagy-associated molecules and OXPHOS proteins in the cochlea.Figure 3.
Cho, S (via Mendeley Data)
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Clonal Mosaicism of Mitochondrial DNA Heteroplasmy as a Molecular Clock of Aging
Aging Cell, Volume 25, Issue 9, September 2026.Mitochondrial DNA mutations diverge by tissue dynamics across lifespan: dividing tissues accumulate pervasive point mutations via clonal stem‐cell expansion, whereas post‐mitotic tissues harbor clonally expanded large‐scale deletions, both culminating in age‐dependent, threshold‐limited respiratory failure.
Renin Chang +5 more
wiley +1 more source