Results 101 to 110 of about 4,311 (206)
Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults A Randomized Clinical Trial [PDF]
IMPORTANCE Aging is associated with a decline in mitochondrial function and reduced exercise capacity. Urolithin A is a natural gut microbiome-derived food metabolite that has been shown to stimulate mitophagy and improve muscle function in older animals
Garcia, Jose M. +8 more
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Targeting mitophagy to activate the recycling of faulty mitochondria during aging is a strategy to mitigate muscle decline. We present results from a randomized, placebo-controlled trial in middle-aged adults where we administer a postbiotic compound ...
Evans, Mal +8 more
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Potential of Urolithin A to improve joint health
Aging, 2023 D’Amico, Davide, Lotz, Martin
openaire +2 more sources
Targeting aging with urolithin A in humans: A systematic review
Ageing Research ReviewsUrolithin A (UA) is a gut metabolite derived from ellagic acid. This systematic review assesses the potential geroprotective effect of UA in humans. In five studies including 250 healthy individuals, UA (10-1000 mg/day) for a duration ranging from 28 days to 4 months, showed a dose-dependent anti-inflammatory effect and upregulated some mitochondrial ...
Kuerec, AH +6 more
openaire +3 more sources
ARO-The Scientific Journal of Koya UniversityCorrosion poses a significant economic and environmental burden, highlighting the need for sustainable corrosion inhibitors. This study investigates the potential of urolithin derivatives (UroE, UroM5, UroM6, and UroM7) as eco-friendly corrosion ...
Rebaz A. Omer
doaj +1 more source
Synthesis of urolithin A 3- and 8-glucuronides via intramolecular biaryl coupling
Results in ChemistryUrolithins, 6H-dibenzo[b,d]pyran-6-one derivatives, are metabolites produced by gut microbiota from ellagic acid, a natural antioxidant. They are more efficiently absorbed than ellagic acid and contribute to the health benefits of ellagitannin-rich foods.
Takanori Nagai +5 more
doaj +1 more source
A concise synthesis of glucuronide metabolites of urolithin-B, resveratrol, and hydroxytyrosol
, 2009 7 páginas, 1 figura, 1 tabla, 4 esquemasA simple and direct strategy to chemically synthesize O-β-d-glucuronides of urolithin-B 4, resveratrol 5, and the corresponding hydroxytyrosol derivatives 6, 7 (as a regioisomeric mixture), and 8 is described.
Alcántara, David +2 more
core +1 more source
Applied SciencesOil extracted from walnuts leaves behind large amounts of defatted press cake that still retains valuable nutrients. Solid state fermentation (SSF) is a promising method to liberate bioactive compounds from food by-products.
Wolfram Manuel Brück +2 more
doaj +1 more source
AntioxidantsObesity is in epidemic proportions in many parts of the world, contributing to increasing rates of non-alcoholic fatty liver disease (NAFLD). NAFLD represents a range of conditions from the initial stage of fatty liver to non-alcoholic steatohepatitis ...
Tharani Senavirathna +3 more
doaj +1 more source