Results 31 to 40 of about 3,771 (207)
Urolithin A alleviates neuropathic pain and activates mitophagy
Molecular Pain, 2023 Neuropathic pain (NP) occurs frequently in the general population and has a negative impact on the quality of life. There is no effective therapy available yet owing to the complex pathophysiology of NP. In our previous study, we found that urolithin A (UA), a naturally occurring microflora-derived metabolite, could relieve NP in mice by inhibiting the
Chenyi Wang +6 more
openaire +2 more sources
Brain Sciences, 2021 Pomegranate juice (PJ) is a rich source of ellagitannins (ETs), precursors of colonic metabolite urolithin A, which are believed to contribute to pomegranate’s neuroprotective effect.
Małgorzata Kujawska +8 more
doaj +1 more source
Frontiers in Pharmacology, 2020 Ellagitannins are signature constituents of oak wood and their consumption has been associated with various health benefits. In vivo, they undergo metabolic degradation including gut microbial metabolism yielding urolithins.
Linda Volpp +5 more
doaj +1 more source
Life, 2022 In our continued study on the anti-HIV activity of compounds present in CareVidTM, we report the HIV-1 integrase ((HIV-1 IN) inhibitory effects of pellitorine (1), oleuropein (2), magnoflorine (3), crotepoxide (4), ent-kaurane-16β,17-diol (5 ...
Winnie Rotich +5 more
doaj +1 more source
Food & Function, 2023 The two bacterial consortia colonized the intestine of rats and converted UM-0 (non-urolithin-producing) animals into urolithin-producing animals mimicking the UM-A and UM-B metabotypes.
Iglesias Aguirre, Carlos Eduardo +7 more
openaire +3 more sources
Frontiers in Microbiology, 2017 Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma +7 more
doaj +1 more source
In vivo anti-inflammatory and antioxidant properties of ellagitannin metabolite urolithin A [PDF]
, 2011 Urolithin A is a major metabolite produced by rats and humans after consumption of pomegranate juice or pure ellagitannin geraniin. In this study, we investigated the anti-inflammatory effect of urolithin A on carrageenan-induced paw edema in mice.
Tai, Akihiro +6 more
core +2 more sources
Interactions between Gut Microbiota and Polyphenols: New Insights into the Treatment of Fatigue
Molecules, 2022 Fatigue seriously affects people’s work efficiency and quality of life and has become a common health problem in modern societies around the world. The pathophysiology of fatigue is complex and not fully clear.
Chuanhong Luo +8 more
doaj +1 more source
, 2022 Urolithins (dibenzo-pyran-[b,d]-6 one derivatives) are human gut microbiota metabolites produced from the natural food antioxidant ellagic acid. Urolithins are better absorbed than ellagic acid and demonstrate biological activities that suggest that they
Laura Trulli (1663636) +11 more
core +1 more source
Tissue deconjugation of urolithin A glucuronide to free urolithin A in systemic inflammation
Food & Function, 2019 Urolithin A glucuronide is deconjugated to free urolithin A in systemic inflammation.
Ávila-Gálvez, María Ángeles +3 more
openaire +5 more sources