Results 51 to 60 of about 3,771 (207)
Urolithins: Diet-Derived Bioavailable Metabolites to Tackle Diabetes [PDF]
Nutrients, 2021 Diabetes remains one of the leading causes of deaths and co-morbidities in the world, with tremendous human, social and economic costs. Therefore, despite therapeutics and technological advancements, improved strategies to tackle diabetes management are still needed. One of the suggested strategies is the consumption of (poly)phenols. Positive outcomes
Ana F. Raimundo +4 more
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, 2021 Mitochondrial dysfunction including deficits of mitophagy is seen in aging and neurodegenerative disorders including Alzheimer's disease (AD). Apart from traditionally targeting amyloid beta (Aβ), the main culprit in AD brains, other approaches include ...
Singh H +9 more
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Urolithins and their possible implications for diabetic kidney
European Journal of Translational and Clinical Medicine, 2022 The increasing prevalence of diabetic kidney disease (DKD), a common complication of type 1 and type 2 diabetes, is becoming a leading risk factor of developing end stage renal disease (ESRD). The multiple mechanisms involved in renal tissue damage are a challenge for effective targeted therapy.
Milena Kotewicz, Barbara Lewko
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Journal of Chemical Research, 2023 Urolithins are the gut microbiota metabolites of ellagitannins which are found in natural plants such as pomegranate, strawberry, and raspberry, and in nuts.
Hecheng Wang +6 more
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Frontiers in Pharmacology, 2021 Scope: Ellagitannins are polyphenols found in numerous fruits, nuts and seeds. The elagitannin punicalagin and its bioactive metabolites ellagic acid and urolithins are discussed to comprise a high potential for therapeutically or preventive medical ...
Nina A. Hering +4 more
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Antiatherogenic effects of ellagic acid and urolithins in vitro
Archives of Biochemistry and Biophysics, 2016 Atherosclerosis, one of the leading causes of death worldwide, is characterized by impaired endothelial function and lipid metabolism, among other factors. Ellagitannins are a class of phenolic compounds that may play a role in cardiovascular health. This work aimed to study the potential atheroprotective effects of urolithins, ellagitannin-derived gut
Laura Mele +8 more
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Urolithin A in Health and Diseases: Prospects for Parkinson’s Disease Management
Antioxidants, 2023 Parkinson’s disease (PD) is a chronic and progressive neurodegenerative disorder characterized by a complex pathophysiology and a range of symptoms. The prevalence increases with age, putting the ageing population at risk. Disease management includes the improvement of symptoms, the comfort of the patient’s life, and palliative care.
Olga Wojciechowska, Małgorzata Kujawska
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Digestive Stability of Tannin-Enriched Fraction of Rubus chingii Hu Fruits and Its Regulatory Effect on the Intestinal Microflora [PDF]
Shipin Kexue, 2023 Tannin is the major active ingredient of the dried unripe fruits of Chinese raspberry (Rubus chingii Hu), Fupenzi in Chinese, and has the functions of lowering blood sugar, reducing blood lipid, resisting inflammation, delaying aging and preventing ...
JIA Xiaoyan, HU Pengpeng, WANG Peixin, DING Qiao, WANG Enhui, XIE Zuohua, TU Zongcai, ZHANG Lu
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Frontiers in Nutrition, 2022 Urolithin A (UA) has received considerable research attention because of its health benefits. However, only a few strains have been reported to produce UA from ellagic acid (EA), and the molecular mechanisms underlying the gut microbiota-mediated ...
Xiaomeng Zhang +20 more
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Anti-Aging Effect of Urolithin A on Bovine Oocytes In Vitro [PDF]
Animals, 2021 Oxidative stress and mitochondrial dysfunction have been associated with the age-related decline of oocyte quality and strategies for their prevention are currently quested. Urolithin A (UA) is a natural metabolite with pro-apoptotic and antioxidant effects, capable of preventing the accumulation of dysfunctional mitochondria in different aged cells ...
Élisa Fonseca +6 more
openaire +4 more sources