Results 21 to 30 of about 114,628,527 (155)

Constituents and Metabolites of a French Oak Wood Extract (Robuvit®) in Serum and Blood Cell Samples of Women Undergoing Hysterectomy

open access: yesFrontiers in Pharmacology, 2020
Ellagitannins are signature constituents of oak wood and their consumption has been associated with various health benefits. In vivo, they undergo metabolic degradation including gut microbial metabolism yielding urolithins.
Linda Volpp   +5 more
doaj   +1 more source

Isolation of Human Intestinal Bacteria Capable of Producing the Bioactive Metabolite Isourolithin A from Ellagic Acid

open access: yesFrontiers in Microbiology, 2017
Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma   +7 more
doaj   +1 more source

Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway

open access: yesFrontiers in Pharmacology, 2023
Acute lung injury (ALI) is a life-threatening disease with high incidence and mortality rates. Urolithin A (UA) is a pomegranate intestinal flora metabolite with anti-inflammatory, antioxidant, and anti-aging properties.
Lejing Lou   +8 more
doaj   +1 more source

Pomegranate derivative urolithin A enhances vitamin D receptor signaling to amplify serotonin-related gene induction by 1,25-dihydroxyvitamin D

open access: yesBiochemistry and Biophysics Reports, 2020
Mediated by the nuclear vitamin D receptor (VDR), the hormonally active vitamin D metabolite, 1,25-dihydroxyvitamin D3 (1,25D), is known to regulate expression of genes impacting calcium and phosphorus metabolism, the immune system, and behavior ...
Sarah Livingston   +9 more
doaj   +1 more source

Elucidating the Anti-Inflammatory and Anti-Diabetic Properties of Urolithin Bioactive Metabolites from Pecan [PDF]

open access: yes, 2023
. Pecans are a rich source of ellagitannins which are not absorbed by humans, rather they are catabolized into urolithins by human gut microbiota and enterohepatic circulation.
Bhargava, Prerna
core   +1 more source

Compositions Comprising Urolithin A And Uses Thereof In Treating Kidney Injury

open access: yes, 2021
The present disclosure provides nanoparticle compositions comprising i) a polymeric nanoparticle, ii) one or more ligands conjugated to the polymeric nanoparticle, and iii) urolithin A. The disclosure also provides methods and pharmaceutical compositions
Majeti, Naga Vankata Ravi Kumar   +3 more
core   +1 more source

Preclinical Evaluation of Oral Urolithin-A for the Treatment of Acute Campylobacteriosis in Campylobacter jejuni Infected Microbiota-Depleted IL-10−/− Mice

open access: yesPathogens, 2020
Human campylobacteriosis represents an infectious enteritis syndrome caused by Campylobacter species, mostly Campylobacter jejuni. Given that C. jejuni infections are rising worldwide and antibiotic treatment is usually not indicated, novel treatment ...
Soraya Mousavi   +3 more
doaj   +1 more source

HIV-1 Integrase Inhibitory Effects of Major Compounds Present in CareVid™: An Anti-HIV Multi-Herbal Remedy

open access: yesLife, 2022
In our continued study on the anti-HIV activity of compounds present in CareVidTM, we report the HIV-1 integrase ((HIV-1 IN) inhibitory effects of pellitorine (1), oleuropein (2), magnoflorine (3), crotepoxide (4), ent-kaurane-16β,17-diol (5 ...
Winnie Rotich   +5 more
doaj   +1 more source

Urolithin B, a newly identified regulator of skeletal muscle mass. [PDF]

open access: yes, 2017
The control of muscle size is an essential feature of health. Indeed, skeletal muscle atrophy leads to reduced strength, poor quality of life, and metabolic disturbances.
Pierre, Nicolas   +15 more
core   +1 more source

Urolithin B: Two-way attack on IAPP proteotoxicity with implications for diabetes

open access: yesFrontiers in Endocrinology, 2022
IntroductionDiabetes is one of the major metabolic diseases worldwide. Despite being a complex systemic pathology, the aggregation and deposition of Islet Amyloid Polypeptide (IAPP), or amylin, is a recognized histopathological marker of the disease ...
Ana F. Raimundo   +15 more
doaj   +1 more source

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