Results 41 to 50 of about 4,964 (226)
Pomegranate ellagitannins inhibit α-glucosidase activity in vitro and reduce starch digestibility under simulated gastro-intestinal conditions [PDF]
, 2014 Pomegranate extract was tested for its ability to inhibit α-amylase and α-glucosidase activity. Pomegranate extract strongly inhibited rat intestinal α-glucosidase in vitro whereas it was a weak inhibitor of porcine α-amylase. The inhibitory activity was
BELLESIA, ANDREA +2 more
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Frontiers in Pharmacology, 2021 Scope: Ellagitannins are polyphenols found in numerous fruits, nuts and seeds. The elagitannin punicalagin and its bioactive metabolites ellagic acid and urolithins are discussed to comprise a high potential for therapeutically or preventive medical ...
Nina A. Hering +4 more
doaj +1 more source
Inhibitory effect of tannins from galls of Carpinus tschonoskii on the degranulation of RBL-2H3 Cells [PDF]
, 2012 In this study, the anti-allergy potency of thirteen tannins isolated from the galls on buds of Carpinus tschonoskii (including two tannin derivatives) was investigated.
Han Junkyu +7 more
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Urolithins and their possible implications for diabetic kidney
European Journal of Translational and Clinical Medicine, 2022 The increasing prevalence of diabetic kidney disease (DKD), a common complication of type 1 and type 2 diabetes, is becoming a leading risk factor of developing end stage renal disease (ESRD). The multiple mechanisms involved in renal tissue damage are a challenge for effective targeted therapy.
Milena Kotewicz, Barbara Lewko
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Urolithins: Diet-Derived Bioavailable Metabolites to Tackle Diabetes [PDF]
Nutrients, 2021 Diabetes remains one of the leading causes of deaths and co-morbidities in the world, with tremendous human, social and economic costs. Therefore, despite therapeutics and technological advancements, improved strategies to tackle diabetes management are still needed. One of the suggested strategies is the consumption of (poly)phenols. Positive outcomes
Ana F. Raimundo +4 more
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Antioxidants, 2020 Urolithin A is a metabolite generated from ellagic acid and ellagitannins by the intestinal microbiota after consumption of fruits such as pomegranates or strawberries.
Guillermo Cásedas +4 more
doaj +1 more source
Maternal pomegranate juice intake and brain structure and function in infants with intrauterine growth restriction: A randomized controlled pilot study. [PDF]
, 2019 Polyphenol-rich pomegranate juice has been shown to have benefit as a neuroprotectant in animal models of neonatal hypoxic-ischemia. No published studies have investigated maternal polyphenol administration as a potential neuroprotectant in at-risk ...
Alexopoulos, Dimitrios +7 more
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A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols. [PDF]
, 2020 Catechol dehydroxylation is a central chemical transformation in the gut microbial metabolism of plant- and host-derived small molecules. However, the molecular basis for this transformation and its distribution among gut microorganisms are poorly ...
Balskus, Emily P +8 more
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Antiatherogenic effects of ellagic acid and urolithins in vitro
Archives of Biochemistry and Biophysics, 2016 Atherosclerosis, one of the leading causes of death worldwide, is characterized by impaired endothelial function and lipid metabolism, among other factors. Ellagitannins are a class of phenolic compounds that may play a role in cardiovascular health. This work aimed to study the potential atheroprotective effects of urolithins, ellagitannin-derived gut
Laura Mele +8 more
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Urolithin A in Health and Diseases: Prospects for Parkinson’s Disease Management
Antioxidants, 2023 Parkinson’s disease (PD) is a chronic and progressive neurodegenerative disorder characterized by a complex pathophysiology and a range of symptoms. The prevalence increases with age, putting the ageing population at risk. Disease management includes the improvement of symptoms, the comfort of the patient’s life, and palliative care.
Olga Wojciechowska, Małgorzata Kujawska
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