Results 61 to 70 of about 114,628,527 (155)
Advanced Science, Volume 13, Issue 55, 5 October 2026.This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun +7 more
wiley +1 more source
Frontiers in Pharmacology, 2022 Urolithin A (UroA) is one of the primary intestinal metabolites of ellagitannins, showing translational potential as a nutritional intervention in humans.
Cong Zhang +9 more
doaj +1 more source
MicrobiologyOpen, Volume 15, Issue 5, October 2026.The graphical abstract illustrates how microbiome‐derived indoles activate the aryl hydrocarbon receptor to restore the intestinal barrier. The picture contrasts the “leaky gut” state with the restored homeostasis achieved through AMPK, Nrf2, and IL‐22 signaling.
Mohammad Ali Mahdiabadi +2 more
wiley +1 more source
, 2019 Urolithins are bioactive gut microbiota metabolites of ellagic acid. Here, we have identified four unknown urolithins in human feces after the intake of a pomegranate extract. The new metabolites occurred only in 19% of the subjects.
Rocío García-Villalba (2099278) +3 more
core +1 more source
Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions
MedComm, Volume 7, Issue 10, October 2026.Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley +1 more source
Polyphenol‐Rich Foods as a Healthy and Sustainable Strategy: Mental Health and Metabolomic Profiling
Molecular Nutrition &Food Research, Volume 70, Issue 19, 15 October 2026.A 12‐week nutritional intervention with cocoa flavanols and red‐berry anthocyanins in older adults improved emotional well‐being and identified metabolomic signatures associated with the intervention through urinary metabolome profiling. ABSTRACT The so‑called demographic transition has increased the prevalence of chronic diseases in adults over 65 ...
María Lucía Gómez Nieto +6 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 18, 30 September 2026.Ellagic acid potentiates RSL3‐induced ferroptosis in PANC‐1 by suppressing the Nrf2/HO‐1 antioxidant defense axis via p38 MAPK activation and Keap1 upregulation. In PDAC cells, constitutive Nrf2/HO‐1 signaling establishes a robust antioxidant shield (GPX4, HO‐1) that limits lipid ROS accumulation and confers ferroptosis resistance.
Jianhua Bai +9 more
wiley +1 more source
Shipin gongye ke-jiIn order to evaluate the effect of Streptococcus thermophilus fermentation on green tea extract and its storage characteristics, this study used Streptococcus thermophilus FUA329 and S.
Shuting HAN +7 more
doaj +1 more source
Cancer Medicine, Volume 15, Issue 9, September 2026.ABSTRACT Background Radiotherapy remains a cornerstone of cancer treatment, while its efficacy is often limited by tumor radioresistance and the risk of normal tissue toxicity. Conventional preclinical models, including two‐dimensional (2D) cell cultures and murine xenografts, exhibit significant limitations in recapitulating human tumor ...
Yixian Zhu +4 more
wiley +1 more source
Shipin gongye ke-jiThis study aimed to establish a systematic framework for enhancing the bioconversion efficiency of ellagic acid to urolithin A by Limosilactobacillus fermentum FUA033 through rational medium engineering, while deciphering the molecular orchestration ...
Gewen ZHANG +7 more
doaj +1 more source