Results 71 to 80 of about 354 (136)

Potential impact of urolithin A on pathways relevant to sleep health: a mini review

Frontiers in Nutrition
Sleep is vital to human health, and poor sleep health has been associated with numerous chronic conditions, including cardiovascular disease, obesity, depression, and type 2 diabetes. Recently, an emerging area of research has focused on the relationship
Ana Clara da C. Pinaffi-Langley, Faris M. Zuraikat, Faris M. Zuraikat, Marie-Pierre St-Onge, Andriy Yabluchanskiy   +4 more
doaj   +1 more source

Urolithin A Attenuates Periodontitis in Mice via Dual Anti-Inflammatory and Osteoclastogenesis Inhibition: A Natural Metabolite-Based Therapeutic Strategy

Molecules
Periodontitis is an inflammatory disease that affects the periodontal supporting tissues. Its cardinal clinical manifestations encompass gingival inflammation, periodontal pocket formation, and alveolar bone resorption. Urolithin A (UA), a gut microbiota-
Yishu Xia, Danni Wu, Linyi Zhou, Xinyu Wu, Jianzhi Chen   +4 more
doaj   +1 more source

Determination of Urolithin A in Health Products by Ultra-High-Performance Liquid Chromatography

Molecules
This study establishes and validates a novel ultra-high-performance liquid chromatography (UHPLC) method for the determination of urolithin A content in health products, a bioactive compound with potential anti-aging properties.
Yue E, Zhuang Wang, Jiahui Nie
doaj   +1 more source

Urolithin-C Suppresses Inflammation by Blocking NF-κB Signaling Pathway in LPS-Induced RAW 264.7 Macrophages

Journal of Inflammation Research
Vani Karadi Manjappa,1,2,* Manjula Mavathuru Venkatappa,3,* Deepadarshan Urs,4 Suliphuldevara Mathada Basavarajaiah,5 Shivakumar Venkataramaiah,3 Sanjana Bai Shivramsingh Mahendranathsingh,1 Sushma Mohan,1 Hunase Rajaiah Pushpavathi,4 ...
Manjappa VK, Venkatappa MM, Urs D, Basavarajaiah SM, Venkataramaiah S, Mahendranathsingh SBS, Mohan S, Pushpavathi HR, Krishnappa DK, Sannaningaiah D   +9 more
doaj  

Ellagitannins (Ellagic Acid, Urolithin A, Urolithin B) Inhibit the Catalytic Activity of Human Recombinant Metalloproteinase 9

Iranian Journal of Pharmaceutical Research
Background: Ellagitannins are well-recognized for their antioxidant, chemopreventive, anti-inflammatory, and neuroprotective efficacy. Due to their poor absorption and extensive catabolism, it is proposed that urolithins, as ellagic acid (EA) metabolites, are the real active molecules exerting these biological functions.
Houssein-Zadeh, Nigar, Sadeghi, Leila, Dehghan, Gholamreza   +2 more
openaire   +2 more sources

Potential of Urolithin A to improve joint health

Aging, 2023
D’Amico, Davide, Lotz, Martin
openaire   +2 more sources

Functionalized hydrogels of CeO2 and Urolithin A synergistically scavenge ROS and activate mitophagy for cartilage repair

Materials Today Bio
In recent years, CeO2 nanoparticles are promising biomaterials due to their excellent biocompatibility and antioxidant properties. This study utilizes a methacrylated gelatin (GelMA) hydrogel platform to construct a dual-functional composite material ...
Chunhui Ma, Bingxuan Hua, Houlei Wang, Tianle Ma, Qi Lv, Zuoqin Yan   +5 more
doaj   +1 more source

Correlation between intestinal microbiota and urolithin metabolism in a human walnut dietary intervention

BMC Microbiology
This study is to investigate the relationship between the intestinal microbiota and urine levels of the ellagic acid-derived polyphenols, the urolithins, in a cohort of subjects following a three-week walnut dietary intervention.
Huijia Liu, John W. Birk, Anthony A. Provatas, Haleh Vaziri, Nuoxi Fan, Daniel W. Rosenberg, Raad Z. Gharaibeh, Christian Jobin   +7 more
doaj   +1 more source

Microbiota-derived urolithin A in monoclonal gammopathies and multiple myeloma therapy

Microbiome
Background Gut microbiota-derived urolithins may influence multiple myeloma (MM) disease progression and treatment. We analyzed urolithins and their associated microbiota in a retrospective cohort of 45 patients with active MM or premalignant disease ...
Alba Rodríguez-García, Raquel Ancos-Pintado, Roberto García-Vicente, Alejandra Ortiz-Ruiz, Andrés Arroyo, Miguel Ángel Navarro, María Luz Morales, Patricia Guevara-Ramirez, Pablo Justo, Nieves López-Muñoz, José Sánchez-Pina, Rafael Alonso, María Victoria Selma, María Dolores Frutos-Lisón, Rocío García-Villalba, Francisco A. Tomás-Barberán, Rosa Ayala, Joaquín Martínez-López, María Linares   +18 more
doaj   +1 more source

Targeting aging with urolithin A in humans: A systematic review

Ageing Research Reviews
Urolithin A (UA) is a gut metabolite derived from ellagic acid. This systematic review assesses the potential geroprotective effect of UA in humans. In five studies including 250 healthy individuals, UA (10-1000 mg/day) for a duration ranging from 28 days to 4 months, showed a dose-dependent anti-inflammatory effect and upregulated some mitochondrial ...
Kuerec, AH, Lim, XK, Khoo, AL, Sandalova, E, Guan, L, Feng, L, Maier, AB   +6 more
openaire   +3 more sources