Results 51 to 60 of about 4,964 (226)
Frontiers in Nutrition, 2022 Urolithin A (UA) has received considerable research attention because of its health benefits. However, only a few strains have been reported to produce UA from ellagic acid (EA), and the molecular mechanisms underlying the gut microbiota-mediated ...
Xiaomeng Zhang +20 more
doaj +1 more source
The Aging Heart: Mitophagy at the Center of Rejuvenation. [PDF]
, 2020 Aging is associated with structural and functional changes in the heart and is a major risk factor in developing cardiovascular disease. Many recent studies have focused on increasing our understanding of the basis of aging at the cellular and molecular ...
Gustafsson, Åsa B, Liang, Wenjing J
core +1 more source
Ellagitannins of the fruit rind of pomegranate (Punica granatum) antagonize in vitro the host inflammatory response mechanisms involved in the onset of malaria [PDF]
, 2010 Background The sun-dried rind of the immature fruit of pomegranate (Punica granatum) is presently used as a herbal formulation (OMARIA, Orissa Malaria Research Indigenous Attempt) in Orissa, India, for the therapy and prophylaxis of malaria.
Mario Dell'Agli +7 more
core +1 more source
Role of the small intestine, colon and microbiota in determining the metabolic fate of polyphenols [PDF]
, 2017 (Poly)phenols are a large group of compounds, found in food, beverages, dietary supplements and herbal medicines. Owing to their biological activities, absorption and metabolism of the most abundant compounds in humans are well understood.
Actis-Goretta +182 more
core +1 more source
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro
Pharmaceutical Biology, 2022 L'urolithine A (UroA) peut inhiber la croissance de nombreuses cellules cancéreuses humaines, mais il n'a pas été rapporté si l'UroA inhibe les cellules de carcinome nasopharyngé (NPC). Pour explorer l'effet inhibiteur de l'UroA sur le NPC et le mécanisme potentiel in vitro.
Yang� Yang +8 more
openaire +3 more sources
Molecules, 2016 The consumption of foodstuffs yielding circulating compounds able to maintain endothelial function by improving nitric oxide (NO) bioavailability can be considered as an effective strategy for cardiovascular disease prevention.
Valentina Spigoni +7 more
doaj +1 more source
Antioxidants, 2022 (1) Background: To explore the association between microbial phenolic metabolites (MPM) and metabolic syndrome (MetS) and its clinical features in adolescents aged 12.02 ± 0.41 years. (2) Methods: a cross-sectional study was conducted in 560 participants
Emily P. Laveriano-Santos +16 more
doaj +1 more source
Exploring the role of LDH in cancer cells through the use of small-molecule inhibitors. [PDF]
, 2018 Metabolic reprogramming represents a potential therapeutic target in cancer. The studies of this thesis work lead to assume the enzyme lactate dehydrogenase (LDH) as key element coordinating neoplastic proliferation and invasive growth, suggesting for ...
Di Ianni, Lorenza <1987>
core +1 more source
Gut microbiota modulation of chemotherapy efficacy and toxicity [PDF]
, 2017 Evidence is growing that the gut microbiota modulates the host response to chemotherapeutic drugs, with three main clinical outcomes: facilitation of drug efficacy; abrogation and compromise of anticancer effects; and mediation of toxicity.
Alexander, James L. +5 more
core +1 more source
Urolithin-A attenuates neurotoxoplasmosis and alters innate response towards predator odor
Brain, Behavior, & Immunity - Health, 2020 Neurotoxoplasmosis, also known as cerebral toxoplasmosis, is an opportunistic chronic infection caused by the persistence of parasite Toxoplasma gondii cysts in the brain.
Sijie Tan, Wen Han Tong, Ajai Vyas
doaj +1 more source