Results 151 to 160 of about 1,983 (203)

Potential link between Gordonibacter pamelaeae and phospholipase C gamma 1 in osteoarthritis. [PDF]

AMB Express
Li S, Zhong S, Zeng C.
europepmc   +1 more source

Urolithins: a Comprehensive Update on their Metabolism, Bioactivity, and Associated Gut Microbiota

Molecular Nutrition and Food Research, 2022
Urolithins, metabolites produced by the gut microbiota from the polyphenols ellagitannins and ellagic acid, are discovered by the research group in humans almost 20 years ago.
Adrián Cortés-Martín, Francisco A Tomas-Barberan, Juan Carlos Espín   +2 more
exaly   +2 more sources

Urolithins Attenuate LPS-Induced Neuroinflammation in BV2Microglia via MAPK, Akt, and NF-κB Signaling Pathways

Journal of Agricultural and Food Chemistry, 2018
Emerging data suggest that urolithins, gut microbiota metabolites of ellagitannins, contribute toward multiple health benefits attributed to ellagitannin-rich foods, including walnuts, red raspberry, strawberry, and pomegranate. However, there is limited
Navindra P Seeram, Hang Ma, Xueshi Huang
exaly   +2 more sources

Pomegranate ellagitannin-gut microbial-derived metabolites, urolithins, inhibit neuroinflammation in vitro

Nutritional Neuroscience, 2019
Objectives: Urolithins, ellagitannin-gut microbial-derived metabolites, have been reported to mediate pomegranate’s neuroprotective effects against Alzheimer’s disease (AD), but there are limited data on their effects against neuroinflammation.
Navindra P Seeram, Hang Ma, Susan Meschwitz   +2 more
exaly   +2 more sources

Pomegranate’s Neuroprotective Effects against Alzheimer’s Disease Are Mediated by Urolithins, Its Ellagitannin-Gut Microbial Derived Metabolites

ACS Chemical Neuroscience, 2016
Pomegranate shows neuroprotective effects against Alzheimer\u27s disease (AD) in several reported animal studies. However, whether its constituent ellagitannins and/or their physiologically relevant gut microbiota-derived metabolites, namely, urolithins (
Navindra P Seeram, Hang Ma, Tao Yuan
exaly   +3 more sources

Ellagic Acid and Polyhydroxylated Urolithins Are Potent Catalytic Inhibitors of Human Topoisomerase II: An in Vitro Study

Journal of Agricultural and Food Chemistry, 2012
Ellagic acid (EA), a natural polyphenol abundant in fruits and common in our diet, is under intense investigation for its chemopreventive activity resulting from multiple effects.
Giuseppe Zagotto, Barbara Gatto, Stefano Moro   +2 more
exaly   +2 more sources

Urolithins impair cell proliferation, arrest the cell cycle and induce apoptosis in UMUC3 bladder cancer cells

Investigational New Drugs, 2017
Ellagitannins have been gaining attention as potential anticancer molecules. However, the low bioavailability of ellagitannins and their extensive metabolization in the gastrointestinal tract into ellagic acid and urolithins suggest that the health ...
Maria Teresa Cruz, Célia M Gomes, Anália Carmo   +2 more
exaly   +2 more sources

Ellagic Acid and Urolithins A and B Differentially Regulate Fat Accumulation and Inflammation in 3T3-L1 Adipocytes While Not Affecting Adipogenesis and Insulin Sensitivity

International Journal of Molecular Sciences, 2020
Ellagic acid (EA) is a component of ellagitannins, present in crops such as pecans, walnuts, and many berries, which metabolized by the gut microbiota forms urolithins A, B, C, or D. In this study, ellagic acid, as well as urolithins A and B, were tested
Woo Young Bang, Luis Cisneros-Zevallos, Claudia Delgadillo Puga   +2 more
exaly   +2 more sources