Results 71 to 80 of about 2,467 (216)

Plasma and Urinary (Poly)phenolic Profiles after 4-Week Red Raspberry (Rubus idaeus L.) Intake with or without Fructo-Oligosaccharide Supplementation

Molecules, 2020
Red raspberries (RRB) are high in anthocyanin- and ellagitannin- type (poly)phenols. This study aimed to investigate the effect of 4-week RRB supplementation on (poly)phenolic metabolism in adults with prediabetes and insulin-resistance (PreDM-IR); and ...
Xuhuiqun Zhang, Amandeep Sandhu, Indika Edirisinghe, Britt M. Burton-Freeman   +3 more
doaj   +1 more source

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

Future Postharvest and Food, EarlyView.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja, Javid Iqbal Mir, Mahendra Kumar Verma, Aamir Hussain Dar   +3 more
wiley   +1 more source

The hope and hype of ellagic acid and urolithins as ligands of SARS-CoV-2 Nsp5 and inhibitors of viral replication

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Non-structural protein 5 (Nsp5) is a cysteine protease that plays a key role in SARS-CoV-2 replication, suppressing host protein synthesis and promoting immune evasion.
Elisa Bianconi, Anna Gidari, Maria Souma, Samuele Sabbatini, Deborah Grifagni, Carlo Bigiotti, Elisabetta Schiaroli, Lucia Comez, Alessandro Paciaroni, Francesca Cantini, Daniela Francisci, Antonio Macchiarulo   +11 more
doaj   +1 more source

Pomegranate (Punica granatum L.): A medicinal plant with myriad biological properties - A short review [PDF]

, 2010
The pomegranate, Punica granatum L., which can be found throughout the Mediterranean region, in Southeast Asia, California and Arizona in USA was in ancient times referred as possessing powers of fertility, abundance and good luck (fruit). The biological
Antunes, Maria Dulce, Miguel, Maria Graça, Neves, M. A.   +2 more
core  

The gut-brain axis, BDNF, NMDA and CNS disorders [PDF]

, 2016
Gastro-intestinal (GI) microbiota and the ‘gut-brain axis’ are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
Maqsood, Raeesah, Stone, Trevor W.
core   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

Gut microbiota functions: metabolism of nutrients and other food components [PDF]

, 2017
The diverse microbial community that inhabits the human gut has an extensive metabolic repertoire that is distinct from, but complements the activity of mammalian enzymes in the liver and gut mucosa and includes functions essential for host digestion. As
A Alonso, A Belenguer, A Bordbar, A Braune, A Braune, A Duda-Chodak, A El Kaoutari, A Heinken, A Heinken, A Heinken, A Heinken, A Heinken, A Karau, A Marcobal, A Matthies, A Matthies, A Mohammed, A Quartieri, A-HM Emwas, A-M Davila, AF Hofmann, AJ Brown, AK Mallett, Almut Heinken, AR Rechner, AR Zomorrodi, AW Walker, AW Walker, B Goodwin, BE Gustafsson, BE Gustafsson, BV Jones, C Manach, C Noecker, CA Kolmeder, CA Kolmeder, CB Cole, CIR Gill, CJ Ziemer, CS Song, D Couteau, DH Mallonee, E Bauer, EA Franzosa, EA Smith, EM Lenz, EP Halmos, F Abram, F Bastos, F Suarez, F Tomas-Barberan, F Vadder De, FA Tomas-Barberan, FA Tomas-Barberan, FE Rowan, FM McIntosh, G Corona, G Falony, G Frost, G Wu, Glenn Gibson, GR Gibson, GR Gibson, GT Macfarlane, GT Macfarlane, GW Tannock, H Bernstein, H Hirokane, H Kettle, H Kettle, H Roume, H Tazoe, HM Said, I Rowland, Ian Rowland, IEJA Francois, Ines Thiele, J Eldere Van, J Pérez-Jiménez, J Trygg, JA Flick, JC Garcia-Canaveras, JC Young, JG Le Blanc, JH Cummings, JJ Eloranta, JK Nicholson, JM Landete, JM Ridlon, JM Ridlon, Jonathan Swann, JR Marchesi, JR Swann, JT Bjerrum, JW Lampe, K Decroos, K Steliou, K Watanabe, Karen Scott, Kieran Tuohy, KP Scott, KR Stayrook, L Hanske, L Hanske, L Marín, L Tasse, L Tomasova, LA Woollett, LV Hooper, M Begley, M Blaut, M Dabek, M Hermanussen, M Rajilić-Stojanović, M Vital, M Watanabe, M Watanabe, MB Biggs, MD Levitt, MGM Kok, MJ Gosalbes, MJ Hill, MV Selma, N Reichardt, NC Verberkmoes, NE Lewis, O Manor, P Kurdi, P Louis, P Louis, P Louis, P Louis, Palsson BØ, PC Pircher, PG Frick, PG Wolf, PJ Turnbaugh, Q Zhang, R Madsen, R Muñoz-Tamayo, RL Kandell, S El Aidy, S Greenblum, S Katsuma, S Lockyer, S Magnúsdóttir, S Possemiers, SA Gibson, SA Joyce, SD Boyd, SF Lajoie, SH Duncan, SH Duncan, SH Hussaini, SM Houten, SN Steinway, SU Christl, SU Christl, T Clavel, T Clavel, T Shashkova, W Xiong, W-L Wang, WR Russell, WR Russell, WR Wikoff, X Shen, X Wei, Y Wang, Z Wang, Z-L Dai, Z-L Dai   +171 more
core   +3 more sources

A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols. [PDF]

, 2020
Catechol dehydroxylation is a central chemical transformation in the gut microbial metabolism of plant- and host-derived small molecules. However, the molecular basis for this transformation and its distribution among gut microorganisms are poorly ...
Balskus, Emily P, Bess, Elizabeth N, Bisanz, Jordan E, Kiamehr, Sina, Le, Chip, Luescher, Michael U, Maini Rekdal, Vayu, Nol Bernadino, Paola, Turnbaugh, Peter J   +8 more
core   +1 more source

Beyond “you are what you eat”: Unlocking gut microbiota‐mediated biotransformation of dietary phytochemicals

iMetaOmics, EarlyView.
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley   +1 more source

The Compound Specific Antibacterial Activities of Major Urolithins and Their Methyl Ethers

Journal of the Turkish Chemical Society, Section A: Chemistry, 2021
The investigation of biological activities of natural products, particularly considering the secondary metabolites, continuously receives attention.
Hayrettin Ozan GÜLCAN, Mehmet İLKTAÇ, Bahareh NOSHADİ, Karar SHUKUR, Mustafa GAZİ   +4 more
doaj   +1 more source