Results 51 to 60 of about 1,721 (201)

Comparative studies of urolithins and their phase II metabolites on macrophage and neutrophil functions [PDF]

, 2020
Purpose Ellagitannins are high molecular weight polyphenols present in high quantities in various food products. They are metabolized by human and animal gut microbiota to postbiotic metabolites-urolithins, bioavailable molecules of a low molecular ...
Granica, Sebastian, Filipek, Agnieszka, Melzig, Matthias F., Zentek, Jürgen, Piwowarski, Jakub, Melzig, Matthias, Moeslinger, Thomas, Kruk, Aleksandra, Piwowarski, Jakub P., Bobowska, Aneta   +9 more
core   +1 more source

Urolithin A attenuates auditory cell senescence by activating mitophagy

Scientific Reports, 2022
AbstractAging of sensory organs is associated with a decline in mitochondrial function and the accumulation of dysfunctional mitochondria. Impaired mitophagy blocks the turnover of dysfunctional mitochondria and leads to their accumulation. Urolithin A (UA) induces mitophagy in various mammalian cells.
Sung Il Cho, Eu-Ri Jo, Hansoo Song
openaire   +3 more sources

In vitro conversion of ellagic acid to urolithin A by different gut microbiota of urolithin metabotype A

Applied Microbiology and Biotechnology
Abstract The metabolite urolithin A, a metabolite of the dietary polyphenol ellagic acid (EA), has significant health benefits for humans. However, studies on the gut microbiota involved in ellagic acid metabolism are limited.
Fuxiang He, Yingying Bian, Yaling Zhao, Mengjie Xia, Shu Liu, Jiajin Gui, Xiaoyue Hou, Yaowei Fang   +7 more
openaire   +2 more sources

Interactions of different urolithins with human serum albumin: Insights from fluorescence spectroscopy

, 2023
Urolithins A, B, and C were studied for their interactions with human serum albumin using fluorescence spectroscopy, revealing distinct binding affinities and quenching behaviors.
Zelenović, Nevena, Filipović, Lidija, Popović, Milica, Kojadinović, Milica   +3 more
core  

The potential antidiabetic properties of green and purple tea [Camellia sinensis (L.) O Kuntze], purple tea ellagitannins, and urolithins [PDF]

, 2023
DATA AVAILABILITY : Data will be made available on request.ETHNOPHARMACOLOGICAL RELEVANCE : Tea (Camellia sinensis) has been consumed for centuries as traditional medicine for various diseases, including diabetes.
Bester, Megan Jean, Tolmie, Morné, Serem, June Cheptoo, Nell, Margo Judith, Apostolides, Zeno   +4 more
core   +1 more source

Enhancing the Efficacy of Radiotherapy in Gastric Adenocarcinoma Cells by Gut Microbiota Metabolites: Implications for Urolithin Combination Therapy

Natural Product Communications
Background Gastric adenocarcinoma (GA) ranks as the fourth leading cause of cancer-related mortality. The clinical effectiveness of radiotherapy in GA patients is often limited by the development of radiation resistance. Urolithins, which are metabolites
Abdolreza Ahmadi, Fatemehsadat Hosseini, Hassan Ostadi, Hamid Gholamhosseinian, Milad Iranshahy, Fatemeh B. Rassouli   +5 more
doaj   +1 more source

Antioxidant and Antiglycation Effects of Cistus × incanus Water Infusion, Its Phenolic Components, and Respective Metabolites

Molecules, 2022
Reactive oxygen and carbonyl species promote oxidative and carbonyl stress, and the development of diabetes, metabolic syndrome, cardiovascular diseases, and others. The traditional herb Cistus × incanus is known for its antioxidant properties; therefore,
Karolina Bernacka, Katarzyna Bednarska, Aneta Starzec, Sylwester Mazurek, Izabela Fecka   +4 more
doaj   +1 more source

Gut microbiota shifts and short‐chain fatty acids alterations in pediatric epilepsy patients on a Mediterranean ketogenic diet

Epileptic Disorders, EarlyView.
Abstract Objective The olive oil–based Mediterranean ketogenic diet (MedKD) may support patients with drug‐resistant epilepsy (DRE) or neurometabolic disorders by integrating ketogenic therapy with the cardiometabolic and neuroprotective advantages of the Mediterranean diet.
Sofia Zouganeli, Evdokia K. Mitsou, Mary Yannakoulia, Evangelia Intze, Konstantinos C. Mountzouris, Smaragdi Fessatou, Achilleas Attilakos, Adamantini Kyriacou, Argyrios Dinopoulos   +8 more
wiley   +1 more source

Effect of urolithins A and B on ectopic endometrial growth in a murine model of endometriosis [PDF]

, 2021
Endometriosis is an often painful disease in reproductive-aged women, in which endometrial-like tissue grows outside the uterine cavity. Since the limited current therapeutic alternatives fail in alleviating the symptoms and based on our previous ...
Mc Cormack, Bárbara Andrea, Bilotas, Mariela Andrea, Barañao, Rosa Ines, Olivares, Carla Noemi, Madanes, Daniela, Ricci, Analía Gabriela   +5 more
core   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source