Results 41 to 50 of about 2,467 (216)

Urolithins: The Gut Based Polyphenol Metabolites of Ellagitannins in Cancer Prevention, a Review

Frontiers in Nutrition, 2021
Cancer as a disease continues to ravage the world population without regard to sex, age, and race. Due to the growing number of cases worldwide, cancer exerts a significant negative impact on global health and the economy. Interestingly, chemotherapy has
Sami A. Al-Harbi, Abdulrasheed O. Abdulrahman, Mazin A. Zamzami, Mazin A. Zamzami, Mohammad Imran Khan, Mohammad Imran Khan   +5 more
doaj   +1 more source

Novel multimetabolite prediction of walnut consumption by a urinary biomarker model in a free-living population: the PREDIMED Study [PDF]

, 2017
The beneficial impact of walnuts on human health has been attributed to their unique chemical composition. In order to characterize the dietary walnut fingerprinting, spot urine samples from two sets of 195 (training) and 186 (validation) individuals ...
Andrés Lacueva, Ma. Cristina, Corella Piquer, Dolores, Estruch Riba, Ramon, Fitó Colomer, Montserrat, Garcia Aloy, Mar, Llorach, Rafael, Martínez-González, Miguel Ángel, 1957-, Ros Rahola, Emilio, Salas Salvadó, Jordi, Tulipani, Sara, Urpí Sardà, Mireia   +10 more
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Urolithin A Is a Dietary Microbiota-Derived Human Aryl Hydrocarbon Receptor Antagonist

Metabolites, 2018
Urolithins (e.g., UroA and B) are gut microbiota-derived metabolites of the natural polyphenol ellagic acid. Urolithins are associated with various health benefits, including attenuation of inflammatory signaling, anti-cancer effects and repression of ...
Gulsum E. Muku, Iain A. Murray, Juan C. Espín, Gary H. Perdew   +3 more
doaj   +1 more source

Role of the small intestine, colon and microbiota in determining the metabolic fate of polyphenols [PDF]

, 2017
(Poly)phenols are a large group of compounds, found in food, beverages, dietary supplements and herbal medicines. Owing to their biological activities, absorption and metabolism of the most abundant compounds in humans are well understood.
Actis-Goretta, Actis-Goretta, Actis-Goretta, Amin, Aura, Azzini, Baba, Baeza, Baldwin, Balentine, Barroso, Blaut, Boonpawa, Boto-Ordonez, Boto-Ordonez, Braune, Bredsdorff, Brett, Brown, Bäckhed, Chen, Cheynier, Claesson, Clifford, Clifford, Clifford, Clifford, Clifford, Collins, Crozier, Cuervo, da Encarnacao, da Silva-Pereira, Dall'asta, de, di Gesso, Duarte, Eid, Etxeberria, Fakhry, Fakhry, Farrell, Farrell, Felberg, Fernandez-Millan, Fournier, Garcia-Alvarez, Gary Williamson, Gaya, Gill, Goedert, Gonzalez-Barrio, Gonzalez-Barrio, Gross, Gu, Guglielmetti, Haddock, Harbowy, Haslam, Hengstmann, Hidalgo, Hollman, Hollman, Holt, Hong, Hoyles, Huang, Jacobs, Jacobs, Janssens, Jenner, Juan, Kasimsetty, Keane, Krga, Krumholz, Kuhnert, Kuhnert, Kuhnle, Kuhnle, Lambert, Lang, Li, Li, Li, Liu, Lommen, Low, Ludwig, Ma, Matthies, Mazzeo, Michael N. Clifford, Monti, Moreno-Indias, Mosele, Mosele, Mosele, Mullen, Mullen, Mullen, Nagy, Neveu, Nielsen, Nozaki, Olthof, Ottaviani, Park, Pascual-Teresa, Peng, Pereira-Caro, Pereira-Caro, Pereira-Caro, Pereira-Caro, Pimpao, Pimpao, Pinto, Plumb, Poquet, Price, Ravn-Haren, Regueiro, Renouf, Rhodes, Romo-Vaquero, Roopchand, Roowi, Saha, Said, Sanchez-Patan, Saura-Calixto, Scalbert, Schantz, Scherbl, Selma, Seo, Shaw, Shaw, Stalmach, Stalmach, Stalmach, Stevens, Stoupi, Stoupi, Stoupi, Tabasco, Taira, Takagaki, Takagaki, Takagaki, Takumi, Tognolini, Truchado, Unno, Vallejo, van der Pijl, van Dorsten, van Duynhoven, Vazquez-Fresno, Verloop, Vetrani, Vinha, Vitaglione, Vogtmann, Wadman, Walker, Wallace, Wang, Wang, Warner, Williamson, Woodward, Woting, Woting, Wu, Xue, Yassin, Yassin, Zamora-Ros, Zamora-Ros, Zamora-Ros, Zhang, Zhou   +182 more
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Pomegranate ellagitannins inhibit α-glucosidase activity in vitro and reduce starch digestibility under simulated gastro-intestinal conditions [PDF]

, 2014
Pomegranate extract was tested for its ability to inhibit α-amylase and α-glucosidase activity. Pomegranate extract strongly inhibited rat intestinal α-glucosidase in vitro whereas it was a weak inhibitor of porcine α-amylase. The inhibitory activity was
BELLESIA, ANDREA, TAGLIAZUCCHI, Davide, VERZELLONI, Elena   +2 more
core   +1 more source

Urolithins and their possible implications for diabetic kidney

European Journal of Translational and Clinical Medicine, 2022
The increasing prevalence of diabetic kidney disease (DKD), a common complication of type 1 and type 2 diabetes, is becoming a leading risk factor of developing end stage renal disease (ESRD). The multiple mechanisms involved in renal tissue damage are a challenge for effective targeted therapy.
Milena Kotewicz, Barbara Lewko
openaire   +2 more sources

Urolithins: Diet-Derived Bioavailable Metabolites to Tackle Diabetes [PDF]

Nutrients, 2021
Diabetes remains one of the leading causes of deaths and co-morbidities in the world, with tremendous human, social and economic costs. Therefore, despite therapeutics and technological advancements, improved strategies to tackle diabetes management are still needed. One of the suggested strategies is the consumption of (poly)phenols. Positive outcomes
Ana F. Raimundo, Sofia Ferreira, Francisco A. Tomás-Barberán, Claudia N. Santos, Regina Menezes   +4 more
openaire   +3 more sources

Non-targeted metabolite profiling highlights the potential of strawberry leaves as a resource for specific bioactive compounds [PDF]

, 2017
Background: The non-edible parts of horticultural crops, such as leaves, contain substantial amounts of valuable bioactive compounds which are currently only little exploited.
Aaby, Alvarez-Suarez, Barve, Bialasiewicz, Buendía, Calderón-Montaño, Concerning the Registration, Evaluation, Day, DuPont, Espín, Everette, Fait, Farag, Giampieri, Gigot, Gulen, Hanhineva, Hanhineva, Hokkanen, Hukkanen, Ibrahim, Karaçelik, Keutgen, Kuczkowia, Kårlund, Kårlund, Lavola, Liberal, Lou, Mahesh, Monagas, Mudnic, Nakamura, Oszmiański, Peschel, Soukas, Stewart, Teleszko, Terao, Tulipani, Vagiri, Wang, Yang   +42 more
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Urolithin A in Health and Diseases: Prospects for Parkinson’s Disease Management

Antioxidants, 2023
Parkinson’s disease (PD) is a chronic and progressive neurodegenerative disorder characterized by a complex pathophysiology and a range of symptoms. The prevalence increases with age, putting the ageing population at risk. Disease management includes the improvement of symptoms, the comfort of the patient’s life, and palliative care.
Olga Wojciechowska, Małgorzata Kujawska
openaire   +3 more sources

Benefits of polyphenols on gut microbiota and implications in human health [PDF]

, 2017
The biological properties of dietary polyphenols are greatly dependent on their bioavailability that, in turn, is largely influenced by their degree of polymerization.
Andrés Lacueva, Ma. Cristina, Cardona, Fernando, Queipo Ortuño, María Isabel, Tinahones, Francisco J., Tulipani, Sara   +4 more
core   +1 more source