Results 61 to 70 of about 1,983 (203)

Effect of urolithins A and B on ectopic endometrial growth in a murine model of endometriosis [PDF]

open access: yes, 2021
Endometriosis is an often painful disease in reproductive-aged women, in which endometrial-like tissue grows outside the uterine cavity. Since the limited current therapeutic alternatives fail in alleviating the symptoms and based on our previous ...
Mc Cormack, Bárbara Andrea   +5 more
core   +1 more source

Mechanistic Insights into the Biological Effects and Antioxidant Activity of Walnut (Juglans regia L.) Ellagitannins: A Systematic Review

open access: yesAntioxidants
Walnuts (Juglans regia L.) are an important source of ellagitannins. They have been linked to positive effects on many pathologies, including cardiovascular disorders, neurodegenerative syndromes, and cancer.
Letiția Mateș   +4 more
doaj   +1 more source

The hope and hype of ellagic acid and urolithins as ligands of SARS-CoV-2 Nsp5 and inhibitors of viral replication

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2023
Non-structural protein 5 (Nsp5) is a cysteine protease that plays a key role in SARS-CoV-2 replication, suppressing host protein synthesis and promoting immune evasion.
Elisa Bianconi   +11 more
doaj   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan   +3 more
wiley   +1 more source

Bifidobacterium pseudocatenulatum INIA P815: The first bacterium able to produce urolithins A and B from ellagic acid

open access: yes, 2018
Urolithins are microbial metabolites derived from ellagic acid by the action of intestinal bacterial. Potential beneficial effects of urolithins A and B on certain types of cancer and on muscular health during aging have been demonstrated.
Medina, Margarita   +9 more
core   +1 more source

In vitro conversion of ellagic acid to urolithin A by different gut microbiota of urolithin metabotype A

open access: yesApplied Microbiology and Biotechnology
Abstract The metabolite urolithin A, a metabolite of the dietary polyphenol ellagic acid (EA), has significant health benefits for humans. However, studies on the gut microbiota involved in ellagic acid metabolism are limited.
Fuxiang He   +7 more
openaire   +2 more sources

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun   +7 more
wiley   +1 more source

The improvement effect of ellagic acid and urolithins on metabolic diseases: Pharmacology and mechanism

open access: yesFood & Medicine Homology
Epidemiological studies have demonstrated that a range of metabolic diseases, particularly type 2 diabetes and obesity, have reached epidemic proportions.
Ying-Hao Wang   +6 more
doaj   +1 more source

Biological activities of Punica granatum L. and the emerging role of metabolomics in enhancing its therapeutic potential: A narrative review [PDF]

open access: yesExploration of Foods and Foodomics
Pomegranate has long been used in Greco-Arab medicine for gastrointestinal, cardiovascular, metabolic, and inflammatory disorders. It has been described to relieve nausea, vomiting, abdominal pain, diarrhoea, palpitations, etc.
Meharunnisa, Fatima Rafique
doaj   +1 more source

Microbiome‐Derived Tryptophan Metabolites Regulate AhR Signaling to Restore Epithelial Barrier Integrity in Inflammatory Bowel Disease

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
The graphical abstract illustrates how microbiome‐derived indoles activate the aryl hydrocarbon receptor to restore the intestinal barrier. The picture contrasts the “leaky gut” state with the restored homeostasis achieved through AMPK, Nrf2, and IL‐22 signaling.
Mohammad Ali Mahdiabadi   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy