Results 21 to 30 of about 1,983 (203)
Urolithins and their possible implications for diabetic kidney [PDF]
, 2022 The increasing prevalence of diabetic kidney disease (DKD), a common complication of type 1 and type 2 diabetes, is becoming a leading risk factor of developing end stage renal disease (ESRD). The multiple mechanisms involved in renal tissue damage are a
Lewko, Barbara, Kotewicz, Milena
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Journal of Chemical Research, 2023 Urolithins are the gut microbiota metabolites of ellagitannins which are found in natural plants such as pomegranate, strawberry, and raspberry, and in nuts.
Hecheng Wang +6 more
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Immunomodulatory Role of Urolithin A on Metabolic Diseases [PDF]
Biomedicines, 2021 Urolithin A (UroA) is a gut metabolite produced from ellagic acid-containing foods such as pomegranates, berries, and walnuts. UroA is of growing interest due to its therapeutic potential for various metabolic diseases based on immunomodulatory properties.
Ashley Mulcahy Toney +4 more
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Urolithins: an update on their metabolism, bioactivity and associated gut microbiota
, 2022 Urolithins, metabolites produced by the gut microbiota from the polyphenols ellagitannins and ellagic acid, are discovered by the research group in humans almost 20 years ago.
Francisco A. Tomás-Barberán +15 more
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Urolithin and Reduced Urolithin Derivatives as Potent Inhibitors of Tyrosinase and Melanogenesis: Importance of the 4-Substituted Resorcinol Moiety [PDF]
International Journal of Molecular Sciences, 2021 We previously reported (E)-β-phenyl-α,β-unsaturated carbonyl scaffold ((E)-PUSC) played an important role in showing high tyrosinase inhibitory activity and that derivatives with a 4-substituted resorcinol moiety as the β-phenyl group of the scaffold resulted in the greatest tyrosinase inhibitory activity.
Sanggwon Lee +13 more
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Molecules, 2022 Osteoarthritis (OA) is the most common form of arthritis affecting both the elderly and the middle-aged population. Although various therapeutics have been developed to arrest the structural deterioration of cartilage, the current treatments are limited ...
Marco Govoni, Francesca Danesi
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Tissue deconjugation of urolithin A glucuronide to free urolithin A in systemic inflammation
Food & Function, 2019 Urolithin A glucuronide is deconjugated to free urolithin A in systemic inflammation.
Ávila-Gálvez, María Ángeles +3 more
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Microbial Metabolite Urolithin B Inhibits Recombinant Human Monoamine Oxidase A Enzyme
Metabolites, 2020 Urolithins are gut microbial metabolites derived from ellagitannins (ET) and ellagic acid (EA), and shown to exhibit anticancer, anti-inflammatory, anti-microbial, anti-glycative and anti-oxidant activities. Similarly, the parent molecules, ET and EA are
Rajbir Singh +4 more
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Foods, 2023 Ellagitannins (ETs) are a large group of bioactive compounds found in plant-source foods, such as pomegranates, berries, and nuts. The consumption of ETs has often been associated with positive effects on many pathologies, including cardiovascular ...
Roxana Banc +3 more
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Ellagic Acid-Derived Urolithins as Modulators of Oxidative Stress [PDF]
, 2020 Oxidative stress is a state of excess of prooxidative species relative to the antioxidant defenses (enzymatic and nonenzymatic) in a living organism.
Marjanovic, Aleksandra +3 more
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