Results 31 to 40 of about 1,427 (175)
Frontiers in Microbiology, 2017 Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma +7 more
doaj +1 more source
Microbial Metabolites in Multiple Sclerosis: Implications for Pathogenesis and Treatment
Frontiers in Neuroscience, 2022 Metabolites produced by the gut microbiota have been shown to play an important role in numerous inflammatory, neuropsychiatric, and neurodegenerative diseases.
Eduardo Duarte-Silva +6 more
doaj +1 more source
Journal of Agricultural and Food Chemistry, 2023 Urolithins are gut microbiota metabolites of ellagic acid. Here, we have identified and chemically characterized a novel urolithin produced from urolithin D (3,4,8,9-tetrahydroxy urolithin) by in vitro incubation with different human gut Enterocloster species under anaerobic conditions. Urolithin G (3,4,8-trihydroxy urolithin) was identified by 1H NMR,
David Beltrán +7 more
openaire +3 more sources
Mitophagy Activation by Urolithin A to Target Muscle Aging
Calcified Tissue International, 2023 AbstractThe age-related loss of skeletal muscle function starts from midlife and if left unaddressed can lead to an impaired quality of life. A growing body of evidence indicates that mitochondrial dysfunction is causally involved with muscle aging. Muscles are tissues with high metabolic requirements, and contain rich mitochondria supply to support ...
Julie Faitg +3 more
openaire +3 more sources
Natural Product CommunicationsBackground Gastric adenocarcinoma (GA) ranks as the fourth leading cause of cancer-related mortality. The clinical effectiveness of radiotherapy in GA patients is often limited by the development of radiation resistance. Urolithins, which are metabolites
Abdolreza Ahmadi +5 more
doaj +1 more source
Urolithins in clinical translation: from gut microbial metabolites to precision interventions
Frontiers in NutritionUrolithins are gut microbiota-derived metabolites generated from ellagitannins and ellagic acid, and have emerged as promising mediators at the diet–microbiota–host interface.
Lingmin Hu, Yingchun Ling, Weifeng Jin
doaj +1 more source
Epileptic Disorders, EarlyView.Abstract Objective The olive oil–based Mediterranean ketogenic diet (MedKD) may support patients with drug‐resistant epilepsy (DRE) or neurometabolic disorders by integrating ketogenic therapy with the cardiometabolic and neuroprotective advantages of the Mediterranean diet.
Sofia Zouganeli +8 more
wiley +1 more source
Urolithin A alleviates neuropathic pain and activates mitophagy
Molecular Pain, 2023 Neuropathic pain (NP) occurs frequently in the general population and has a negative impact on the quality of life. There is no effective therapy available yet owing to the complex pathophysiology of NP. In our previous study, we found that urolithin A (UA), a naturally occurring microflora-derived metabolite, could relieve NP in mice by inhibiting the
Chenyi Wang +6 more
openaire +2 more sources
The Compound Specific Antibacterial Activities of Major Urolithins and Their Methyl Ethers
Journal of the Turkish Chemical Society, Section A: Chemistry, 2021 The investigation of biological activities of natural products, particularly considering the secondary metabolites, continuously receives attention.
Hayrettin Ozan GÜLCAN +4 more
doaj +1 more source
Food Biomacromolecules, EarlyView.Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley +1 more source