Results 81 to 90 of about 2,363 (194)
The role of antifungals agents on Candida glabrata biofilms matrix composition [PDF]
, 2010 Candida glabrata was considered, for years, a relatively non-pathogenic saprophyte of the normal flora of healthy individuals and as no causative agent of serious infection in humans.
Azeredo, Joana +5 more
core
Exploring the role of LDH in cancer cells through the use of small-molecule inhibitors. [PDF]
, 2018 Metabolic reprogramming represents a potential therapeutic target in cancer. The studies of this thesis work lead to assume the enzyme lactate dehydrogenase (LDH) as key element coordinating neoplastic proliferation and invasive growth, suggesting for ...
Di Ianni, Lorenza <1987>
core +1 more source
Comparative studies of urolithins and their phase II metabolites on macrophage and neutrophil functions [PDF]
, 2020 Purpose Ellagitannins are high molecular weight polyphenols present in high quantities in various food products. They are metabolized by human and animal gut microbiota to postbiotic metabolites-urolithins, bioavailable molecules of a low molecular ...
Bobowska, Aneta +7 more
core +1 more source
Experimental Physiology, EarlyView.Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi +5 more
wiley +1 more source
Food & Function, 2023 The two bacterial consortia colonized the intestine of rats and converted UM-0 (non-urolithin-producing) animals into urolithin-producing animals mimicking the UM-A and UM-B metabotypes.
Carlos E. Iglesias-Aguirre +7 more
openaire +2 more sources
Antioxidants, 2022 This study aimed to develop and validate a liquid chromatography/electrospray ionization-linear ion trap quadrupole-Orbitrap-high-resolution mass spectrometry (HPLC/ESI-LTQ-Orbitrap-HRMS) method to identify and quantify urinary microbial phenolic ...
Emily P. Laveriano-Santos +18 more
doaj +1 more source
The role of the gut microbiota in colorectal cancer causation [PDF]
, 2019 Here, we reviewed emerging evidence on the role of the microbial community in colorectal carcinogenesis. A healthy gut microbiota promotes intestinal homeostasis and can exert anti-cancer effects; however, this microbiota also produces a variety of ...
Alhinai, Eiman A. +2 more
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Food Frontiers, Volume 7, Issue 2, March 2026.The diagram of the mechanism of action by which UroA regulates RF. ABSTRACT The global prevalence and mortality rates associated with chronic kidney disease (CKD) have been on a continuous rise over recent decades. Renal fibrosis (RF) serves as a critical factor in the progression of CKD to end‐stage renal disease.
Xue Wu +8 more
wiley +1 more source
Urolithins and their possible implications for diabetic kidney
European Journal of Translational and Clinical Medicine, 2022 The increasing prevalence of diabetic kidney disease (DKD), a common complication of type 1 and type 2 diabetes, is becoming a leading risk factor of developing end stage renal disease (ESRD). The multiple mechanisms involved in renal tissue damage are a challenge for effective targeted therapy.
Milena Kotewicz, Barbara Lewko
openaire +2 more sources
Therapeutic efficacy of gut microbiota-derived polyphenol metabolite Urolithin A
Beni-Suef University Journal of Basic and Applied SciencesBackground Despite rising public awareness and improvements in diagnostic and treatment methods, there are adverse effects brought on by drug resistance, an increase in overall treatment costs, and unanticipated side effects from pharmaceuticals.
Shilpa S. Shetty +2 more
doaj +1 more source