Results 1 to 10 of about 5,130,717 (259)

Radioimmunoassay of ursodeoxycholic acid in serum.

Journal of Lipid Research, 1978
A sensitivie and specific radioimmunoassay for the measurement of serum ursodeoxycholic acid has been developed. Ursodeoxycholic acid bound to bovine serum albumin was used as an antigen, and antiserum to this antigen was raised in the rabbit.
I Makino, A Tashiro, H Hashimoto, S Nakagawa, I Yoshizawa   +4 more
doaj   +3 more sources

Metabolic effects of ursodeoxycholic acid in patients with non-alcoholic fatty liver disease

Лечащий Врач
Background. Nonalcoholic fatty liver disease is by far the most common chronic liver disease worldwide with a global prevalence of 32.4%. Currently, there is an active search for new therapeutic options for the management of patients with nonalcoholic ...
V. A. Akhmedov
doaj   +2 more sources

Ursodeoxycholic acid acts as an ileal FXR agonist in male mice with hepatic deficiency of FXR. [PDF]

eGastroenterology
Henry ZR, Maliha S, Basaly V, Yang Z, Taylor RE, Otersen K, Meadows V, Rizzolo D, Stofan M, Bhattacharya A, Zhou P, Brinker A, Yang I, Zhang L, Joseph LB, Buckley B, Kong B, Guo GL.   +17 more
europepmc   +3 more sources

Use of Ursodeoxycholic Acid and the Risk of Severe Coronavirus Disease 2019 in Elderly Patients with Viral Hepatitis. [PDF]

Intern Med
Okushin K, Ikeuchi K, Saito M, Kishida T, Kado A, Fujishiro M, Moriya K, Yotsuyanagi H, Koike K, Tsutsumi T.   +9 more
europepmc   +3 more sources

Ursodeoxycholic Acid Alone Is Effective and Safe to Treat Cholestatic Checkpoint Inhibitor-Induced Liver Injury. [PDF]

Liver Int
Hountondji L, Faure S, Palassin P, Pageaux GP, Maria ATJ, Meunier L.   +5 more
europepmc   +3 more sources

Ursodeoxycholic acid

Gastroenterologie a hepatologie, 2016
J. Beare-Rogers, A. Dieffenbacher, J. V. Holm   +2 more
  +5 more sources

Synthesis and intestinal metabolism of ursodeoxycholic acid conjugate with an antiinflammatory agent, 5-aminosalicylic acid

Journal of Lipid Research, 1998
5-Aminosalicylic acid conjugate of ursodeoxycholic acid was synthesized in above 90% yield by adding a basic solution of 5-aminosalicylic acid into the mixed anhydride formed with ursodeoxycholic acid and ethyl chloroformate.
Ashok K. Batta, G. Stephen Tint, Guorong Xu, Sarah Shefer, Gerald Salen   +4 more
doaj   +1 more source

Characterization of serum and urinary bile acids in patients with primary biliary cirrhosis by gas-liquid chromatography-mass spectrometry: effect of ursodeoxycholic acid treatment.

Journal of Lipid Research, 1989
We have studied the effect of ursodeoxycholic acid on the serum and urinary bile acids in seven patients with moderate to severe primary biliary cirrhosis.
A K Batta, R Arora, G Salen, G S Tint, D Eskreis, S Katz   +5 more
doaj   +1 more source

Ursodeoxycholic acid, chenodeoxycholic acid, and 7-ketolithocholic acid are primary bile acids of the guinea pig.

Journal of Lipid Research, 1990
Guinea pig gallbladder bile contains chenodeoxycholic acid (62 +/- 5%), ursodeoxycholic acid (8 +/- 5%), and 7-ketolithocholic acid (30 +/- 5%). All three bile acids became labeled to the same specific activity within 30 min after [3H]cholesterol was ...
GS Tint, GR Xu, AK Batta, S Shefer, W Niemann, G Salen   +5 more
doaj   +1 more source

Changes in biliary lipid and biliary bile acid composition in patients after administration of ursodeoxycholic acid.

Journal of Lipid Research, 1978
Twenty-three patients with gallstones were treated with two dosage levels of ursodeoxycholic acid, 600 mg/day and 150 mg/day. Two to three months after the treatment, the molar percentage of cholesterol in bile significantly decreased (from 7.4 to 4.5 ...
I Makino, S Nakagawa
doaj   +1 more source